Voritrol 200 mg Injection

Composition of Voritrol 200 mg Injection

Voritrol 200 mg Injection contains Voriconazole 200 mg (as sterile lyophilized powder) for injection. It belongs to the Triazole antifungal (azole) class of medicines.

Uses of Voritrol 200 mg Injection

• Treatment of serious fungal infections such as invasive aspergillosis
• serious Candida infections (including fluconazole-resistant)
• and other invasive fungal infections as per physician assessment

Key benefits

• Treats invasive aspergillosis
• Effective against serious Candida infections
• Option for severe systemic fungal infections when oral therapy is not feasible
• IV therapy for hospitalized/critical patients

How Voritrol 200 mg Injection works

Voriconazole is a triazole antifungal that inhibits fungal cytochrome P450–dependent 14-α-sterol demethylase. This blocks ergosterol synthesis, leading to defective fungal cell membrane formation and inhibition of fungal growth.

How to take Voritrol 200 mg Injection

For intravenous use only. Reconstitute and dilute as directed in the product label and administer as IV infusion by a healthcare professional. Dose and duration depend on indication, body weight, liver function and clinical response; may be given with or without food (IV route).

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause vomiting, liver injury and heart rhythm disturbance. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Voritrol 200 mg Injection

Most side effects of Voritrol are mild and settle as the body adjusts. Reported side effects include:

• Visual disturbances (blurred vision
• photophobia
• color vision changes)
• fever
• nausea
• vomiting
• diarrhea
• abdominal pain
• headache
• rash
• liver enzyme elevation
• infusion-site reactions

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Voritrol 200 mg Injection

Warnings and precautions

Prescription-only medicine; IV administration under medical supervision. Monitor liver function (risk of hepatitis/hepatic failure) and discontinue if significant toxicity occurs. Can cause visual disturbances and photosensitivity/phototoxicity; avoid excessive sunlight and use protection. Risk of QT prolongation/arrhythmias—use caution in patients with cardiac disease, electrolyte abnormalities, or when combined with QT-prolonging drugs. Use caution and dose adjustment/monitoring in hepatic impairment; monitor renal function (IV formulation excipients may affect patients with renal impairment).

Do not take Voritrol if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with active liver disease, and several are not for use in pregnancy. Itraconazole is not for people with heart failure.

Interactions with other medicines

Strong interaction potential via CYP3A4/CYP2C19/CYP2C9: contraindicated/avoid with rifampicin, carbamazepine, long-term phenytoin/high-dose ritonavir, St John’s wort; may increase levels of warfarin, cyclosporine, tacrolimus, sirolimus, certain statins, benzodiazepines, sulfonylureas; caution with QT-prolonging medicines and drugs affecting electrolytes

How to store Voritrol 200 mg Injection

Store as per label in original pack, protected from light and moisture, at controlled room temperature (generally below 25°C). After reconstitution/dilution, use within recommended time and storage conditions specified in the package insert.

Expert advice for Voritrol 200 mg Injection

Complete the full course, however long. Keep the skin clean and dry, wash clothes and bedding in hot water, and treat family members if they are affected, or reinfection is very likely.

Manufacturer and class

Manufacturer:

LUPIN LAB

Therapeutic class:

Antifungal

Drug class:

Triazole antifungal (azole)