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Prescription requiredUnizaDERMA

Zaclo-G Cream

Clobetasol (0.05% w/w) + Gentamicin (0.1% w/w)

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Zaclo-G Cream is used for bacterial skin infections.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Clobetasol (0.05% w/w) + Gentamicin (0.1% w/w)
Available variants: cream 0.05%w/w + 0.1%w/w 20GM
Best price: ₹21 (₹1.07 per g)
MRP: ₹23
Prescription: Required
Manufacturer: UNIZA

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Zaclo-G Cream

Zaclo-G Cream contains Clobetasol (0.05% w/w) + Gentamicin (0.1% w/w). It belongs to the Corticosteroid / calcineurin inhibitor and Antibacterial agent class of medicines.

Uses of Zaclo-G Cream

Bacterial skin infections

Key benefits

  • In Bacterial skin infections Zaclo-G Cream is a combination of medicines used to treat skin infections caused by microorganisms such as bacteria. It kills and stops the growth of infection causing microorganisms
  • thereby clearing the infection and relieving the symptoms. It also blocks the release of chemicals that cause symptoms such as itching
  • redness and swelling. Therefore this medicine relieves the inflammation due to these infections. You should use Zaclo-G Cream for as long as it is prescribed
  • even if your symptoms disappear
  • otherwise they may come back. Depending on the type of infection you are treating
  • this may be several weeks. Even after your infection is completely cured
  • you may have to apply it occasionally to prevent the symptoms from returning.

How Zaclo-G Cream works

Zaclo-G Cream is a combination of two medicines: Clobetasol and Gentamicin, which treats bacterial skin infections. Clobetasol is a steroid medicine. It blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen and itchy. Gentamicin is an antibiotic. It stops bacterial growth by preventing the synthesis of essential proteins required by the bacteria to carry out vital functions.

How to take Zaclo-G Cream

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Zaclo-G Cream, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can suppress the body's own steroid production when it is used for a long time over large areas, especially in children. It can cause vomiting, severe loose motions and nerve symptoms. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Zaclo-G Cream

Most side effects of Zaclo-G are mild and settle as the body adjusts. Reported side effects include:

  • Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Zaclo-G Cream

PregnancyPregnancy CONSULT YOUR DOCTOR
BreastfeedingBreast feeding CONSULT YOUR DOCTOR
AlcoholAlcohol
DrivingDriving
KidneyKidney
LiverLiver
Habit formingNo

Warnings and precautions

Use it only on the area and for the number of days your doctor specified. Potent steroid creams thin the skin permanently when used for too long. Never use a potent steroid cream on the face, the groin or the underarms unless your doctor has specifically told you to — the skin there is thin and absorbs much more. Do not use it on an infection. A steroid on ringworm, impetigo or herpes makes the infection worse while hiding it. Do not use leftover cream on a new rash, and never pass it to someone else. Stop and see your doctor if the area becomes more painful, weepy or crusted. Finish the whole course even after you feel better. Do not drink any alcohol while taking metronidazole, ornidazole or tinidazole, or for the period after the course that your doctor states — the combination causes severe flushing, vomiting and a racing heart. Report severe or watery loose motions during or after the course rather than treating them yourself. Tetracyclines stain developing teeth and are avoided in young children and in pregnancy. Antibiotics do not work against colds, flu or most sore throats, which are caused by viruses.

Do not take Zaclo-G if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for untreated bacterial, fungal or viral skin infections. Not for use in or around the eyes.

Interactions with other medicines

No significant interactions are expected from preparations used on the skin. Antacids, iron, zinc and calcium reduce the absorption of tetracyclines — separate them by a couple of hours. Tell your doctor if you take a blood thinner.

How to store Zaclo-G Cream

Store below 30°C, away from direct sunlight. Close the cap tightly after each use. Keep out of the reach of children.

Expert advice for Zaclo-G Cream

Zaclo-G Cream may take several weeks to show its action. Keep using it as suggested by your doctor. Wash your skin with a mild cleanser and pat it dry before applying Zaclo-G Cream. Apply it as a thin layer onto clean, dry, unbroken skin affected by acne. It may cause minor burning, stinging or irritation when applied. Inform your doctor if this does not go away. Avoid contact with your eyes, nose or mouth. Rinse it off with water if you accidentally get the cream in these areas. It is advisable not to touch or scratch the infected area as it can worsen the situation.

Manufacturer and class

Manufacturer:
UNIZA
Therapeutic class:
DERMA
Drug class:
Corticosteroid / calcineurin inhibitor and Antibacterial agent

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Zaclo-G Cream FAQs

What is Zaclo-G Cream used for?
Zaclo-G Cream is commonly used for Bacterial skin infections. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Zaclo-G Cream?
Zaclo-G Cream contains Clobetasol (0.05% w/w) + Gentamicin (0.1% w/w). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Zaclo-G Cream?
This medicine is for external use only. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Zaclo-G Cream work?
Zaclo-G Cream is a combination of two medicines: Clobetasol and Gentamicin, which treats bacterial skin infections.
Is Zaclo-G Cream a prescription medicine?
Yes. Zaclo-G Cream is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Zaclo-G Cream?
The side effects reported most often with Zaclo-G are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Zaclo-G Cream be taken during pregnancy?
Pregnancy CONSULT YOUR DOCTOR Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Zaclo-G.
Can I drink alcohol while taking Zaclo-G Cream?
Alcohol
What if I miss a dose of Zaclo-G Cream?
If you miss a dose of Zaclo-G Cream, apply it as soon as possible.
Is Zaclo-G Cream habit forming?
No. Zaclo-G Cream is not known to be habit forming when taken as prescribed.
How much does Zaclo-G Cream cost on PingMeDoc Pharmacy?
Zaclo-G Cream starts at ₹21 (MRP ₹23) on PingMeDoc Pharmacy. Available in cream 0.05%w/w + 0.1%w/w 20GM. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Zaclo-G Cream?
Zaclo-G Cream is manufactured by UNIZA. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Zaclo-G Cream delivered?
Zaclo-G Cream is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Zaclo-G Cream, Quick facts

Salt
Clobetasol (0.05% w/w) + Gentamicin (0.1% w/w)
Form
cream
Best price
₹21 (₹1.07 per g)
MRP
₹23
Prescription
Required (Rx)
Schedule
Schedule H
Brand
UNIZA
Manufacturer
UNIZA
Therapeutic class
DERMA
Drug class
Corticosteroid / calcineurin inhibitor and Antibacterial agent
Habit forming
No
Variants
cream 0.05%w/w + 0.1%w/w 20GM
Delivery
Standard across India

References

Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Zaclo-G Cream.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.