Ziglim 2

Composition of Ziglim 2

Ziglim 2 contains Glimepiride 2 mg (tablet). It belongs to the Sulfonylurea class of medicines.

Uses of Ziglim 2

• Treatment of type 2 diabetes mellitus in adults
• as an adjunct to diet and exercise to improve glycaemic control (alone or with other antidiabetic medicines as prescribed).

Key benefits

• Lowers blood glucose in type 2 diabetes
• Improves insulin secretion
• Helps reduce fasting and post-meal sugar levels
• Supports HbA1c control when combined with diet and exercise

How Ziglim 2 works

Glimepiride is a sulfonylurea that stimulates insulin release from pancreatic beta cells by closing ATP-sensitive potassium channels. This increases insulin secretion and helps lower blood glucose levels, mainly in type 2 diabetes.

How to take Ziglim 2

Take by mouth exactly as prescribed, usually once daily with breakfast or the first main meal. Swallow tablet with water; do not skip meals to reduce risk of low blood sugar. Dose is individualized based on blood glucose/HbA1c; follow doctor’s advice for titration.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Ziglim 2

Most side effects of Ziglim are mild and settle as the body adjusts. Reported side effects include:

• Hypoglycaemia (low blood sugar)
• dizziness
• headache
• nausea
• stomach upset
• weight gain
• skin rash/itching

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Ziglim 2

Warnings and precautions

May cause hypoglycaemia—risk increases with missed meals, excessive exercise, alcohol, or dose errors; carry a fast-acting sugar source. Use with caution in kidney or liver impairment and in elderly; dose adjustment/monitoring may be needed. Inform doctor if you have G6PD deficiency (risk of hemolysis) or sulfonamide allergy. Not for type 1 diabetes or diabetic ketoacidosis. If symptoms of severe allergy (swelling, breathing difficulty) or jaundice occur, seek medical help.

Do not take Ziglim if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease.

Interactions with other medicines

Other antidiabetics/insulin (increased hypoglycaemia), alcohol (unpredictable glucose effects), beta-blockers (may mask hypoglycaemia symptoms), azole antifungals (e.g., fluconazole), macrolides (e.g., clarithromycin), quinolones, NSAIDs/salicylates, warfarin, ACE inhibitors (may enhance effect), corticosteroids/thiazide diuretics/thyroid hormones (may increase blood glucose), rifampicin/phenytoin (may reduce effect).

How to store Ziglim 2

Store below 25°C in a dry place, protected from light and moisture. Keep in original blister pack and out of reach of children.

Expert advice for Ziglim 2

Take it shortly before a meal, and eat that meal. Check your sugar as often as your doctor has asked, especially when your routine changes.

Manufacturer and class

Manufacturer:

FDC LIMITED

Therapeutic class:

Antidiabetic

Drug class:

Sulfonylurea