Zoryl 0.5 mg Tablet

Composition of Zoryl 0.5 mg Tablet

Zoryl 0.5 mg Tablet contains Glimepiride 0.5 mg. It belongs to the Sulfonylurea class of medicines.

Uses of Zoryl 0.5 mg Tablet

• Type 2 diabetes mellitus (adult) to help control blood sugar
• usually along with diet and exercise; may be used alone or with other antidiabetic medicines.

Key benefits

• Lowers fasting and post-meal blood sugar
• Improves glycaemic control in type 2 diabetes
• Helps reduce risk of diabetes complications when sugars are controlled
• Once-daily dosing option

How Zoryl 0.5 mg Tablet works

Glimepiride is a sulfonylurea that stimulates the pancreas to release insulin. It also improves peripheral insulin sensitivity, thereby lowering blood glucose levels.

How to take Zoryl 0.5 mg Tablet

Oral tablet. Take exactly as prescribed, usually once daily with breakfast or the first main meal. Swallow with water; do not skip meals after taking it. Dose is individualized based on blood glucose and HbA1c; monitor sugars regularly.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take the missed dose of Zoryl as soon as you remember. If it is almost time for the next dose, skip the missed one and carry on with the usual schedule. Do not take two doses together to make up for a missed dose.

If you take too much

Taking more Zoryl than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.

Side effects of Zoryl 0.5 mg Tablet

Most side effects of Zoryl are mild and settle as the body adjusts. Reported side effects include:

• Hypoglycaemia (low blood sugar)
• dizziness
• headache
• nausea
• abdominal discomfort
• diarrhoea
• weight gain
• skin rash

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Zoryl 0.5 mg Tablet

Warnings and precautions

Risk of hypoglycaemia—more likely with missed meals, excessive exercise, alcohol intake, elderly patients, liver/kidney impairment, or when combined with other antidiabetics. Use with caution in hepatic or renal disease; dose adjustment/close monitoring may be required. Avoid driving/operating machinery if you experience symptoms of low blood sugar. Inform doctor if you have sulfonamide allergy, G6PD deficiency (risk of haemolysis), severe infection, trauma or surgery (may require insulin). Not for type 1 diabetes or diabetic ketoacidosis.

Interactions with other medicines

Other antidiabetics (insulin, metformin) may increase hypoglycaemia risk; beta-blockers may mask hypoglycaemia symptoms; ACE inhibitors can potentiate glucose-lowering effect; corticosteroids, thiazide/loop diuretics, oral contraceptives, thyroid hormones and sympathomimetics may raise glucose; azole antifungals (e.g., fluconazole), macrolides, chloramphenicol may increase effect; rifampicin, phenytoin, carbamazepine may reduce effect; warfarin interaction possible—monitor INR; alcohol increases hypoglycaemia risk.

How to store Zoryl 0.5 mg Tablet

Store below 25°C in a dry place. Protect from light and moisture. Keep out of reach of children.

Manufacturer and class

Manufacturer:

INTAS PHARMACEUTICALS`

Therapeutic class:

Antidiabetic

Drug class:

Sulfonylurea