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Dr Reddys Laboratories Ltd - Tablet - 100mg + 325mg + 65mg - 10 S
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Ambroxol (30mg/5ml) + Guaifenesin (50mg/5ml) + Terbutaline (1.25mg/5ml)
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Zyrcof Syrup 100 ml is used for relief of dry (non-productive) cough and associated throat irritation in common cold/upper respiratory tract infections (as prescribed).
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Zyrcof Syrup 100 ml contains Ambroxol (30mg/5ml) + Guaifenesin (50mg/5ml) + Terbutaline (1.25mg/5ml). It belongs to the Cough & cold combination (varies by formulation) class of medicines.
Relief of dry (non-productive) cough and associated throat irritation in common cold/upper respiratory tract infections (as prescribed).
ZYRCOF is a cough syrup brand; the exact ingredients may vary by formulation. In general, antitussive components suppress the cough reflex, while antihistamines reduce allergy-related irritation and decongestants may relieve nasal congestion if present.
Shake well before use. Measure dose with a calibrated cup/spoon and take as advised by a doctor. Can be taken with or without food; if it upsets the stomach, take after food. Do not exceed the recommended dose; avoid combining with other cough/cold products unless advised.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause vomiting, severe drowsiness, a racing heart and, with codeine, dangerously slow breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Zyrcof are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Consult doctor |
|---|---|
| Breastfeeding | Consult your doctor before using this while breastfeeding. |
| Alcohol | Avoid |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Use with caution if you have kidney disease — your doctor may adjust the dose or monitor your kidney function. |
| Liver | Use with caution if you have liver disease — your doctor may adjust the dose or monitor your liver function. |
| Habit forming | No |
Exact composition not confirmed—verify label before dispensing/using. May cause drowsiness; avoid driving or operating machinery. Use with caution in children, elderly, glaucoma, prostate enlargement/urinary retention, liver disease, and asthma/COPD unless prescribed. Do not use longer than advised; seek medical help if cough persists >7 days, or with fever, wheeze, shortness of breath, or blood in sputum.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Codeine-containing preparations are not for children, or for anyone with breathing difficulty.
Alcohol and other CNS depressants (increased sedation), sedating antihistamines, MAO inhibitors (if formulation contains dextromethorphan or certain decongestants), serotonergic drugs such as SSRIs/SNRIs/triptans/linezolid (serotonin syndrome risk if dextromethorphan present)
Store below 25°C, protected from light and moisture. Keep bottle tightly closed. Do not freeze. Keep out of reach of children.
Drink plenty of water — it thins mucus better than any syrup. Steam inhalation helps congestion and costs nothing. Measure the dose with the cup supplied.

Dr Reddys Laboratories Ltd - Tablet - 100mg + 325mg + 65mg - 10 S
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The information on Zyrcof Syrup 100 ml is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.