Brilinta 90 Tablet

Drug | Tablet

Prevention of atherothrombotic events (heart attack, stroke, cardiovascular death) in adults with acute coronary syndrome (ACS) or history of myocardial infarction; used with low-dose aspirin as prescribed.

Ticagrelor is a P2Y12 receptor antagonist that reversibly inhibits ADP-mediated platelet activation and aggregation. This reduces clot formation in coronary arteries and stents, lowering the risk of recurrent cardiovascular events.

Take exactly as prescribed, usually twice daily with or without food. Often used with low-dose aspirin (commonly 75-100 mg/day). Do not stop suddenly without medical advice; if a dose is missed, take the next dose at the usual time.

Bleeding, bruising, nosebleed, shortness of breath (dyspnea), headache, dizziness, nausea, diarrhea

Increases risk of bleeding; seek urgent care for unusual bleeding, black stools, blood in urine, or coughing/vomiting blood. Tell your doctor before surgery/dental procedures. Not recommended in active pathological bleeding or history of intracranial hemorrhage. Use caution in severe liver disease, gout/hyperuricemia, and if you develop troublesome breathlessness.

Strong CYP3A inhibitors (ketoconazole, clarithromycin, ritonavir), strong CYP3A inducers (rifampicin, carbamazepine, phenytoin), anticoagulants and other antiplatelets (warfarin, heparin, NOACs, clopidogrel) increase bleeding risk, NSAIDs increase bleeding risk, simvastatin/lovastatin high doses, digoxin (monitor levels)

Store at room temperature in a dry place, protected from moisture. Keep in original blister pack until use.

Ticagrelor 90 mg Tablet (generic), Brilinta 90 mg (same brand), Ticagrelor by other brands (where available), Clopidogrel 75 mg (therapeutic alternative), Prasugrel 10 mg (therapeutic alternative)