Nebivie 5MG Tab

Tablet

Treatment of hypertension (high blood pressure); may be used in stable chronic heart failure as advised by a doctor.

Nebivolol is a selective beta-1 adrenergic blocker that lowers heart rate and reduces the force of contraction, decreasing cardiac workload and blood pressure. It also enhances nitric oxide–mediated vasodilation, helping relax blood vessels.

Take orally exactly as prescribed, usually once daily at the same time each day, with or without food. Swallow with water; do not stop suddenly without medical advice. Dose adjustment may be needed in elderly or kidney/liver problems.

Headache,dizziness,fatigue,bradycardia (slow heart rate),nausea,diarrhoea,constipation,shortness of breath,cold hands/feet

Do not use in severe bradycardia, sick sinus syndrome (without pacemaker), second/third-degree AV block, cardiogenic shock, severe hypotension, severe heart failure not stabilized, or severe liver impairment. Use with caution in asthma/COPD, diabetes (may mask hypoglycaemia symptoms), thyroid disorders, peripheral vascular disease, and in patients with conduction disorders. Do not stop abruptly (risk of rebound angina/hypertension); taper under medical supervision. Monitor blood pressure and pulse; seek care for fainting, wheeze, or worsening breathlessness/edema.

Other antihypertensives (additive BP lowering),calcium channel blockers (verapamil/diltiazem),antiarrhythmics (amiodarone,quinidine),digoxin,clonidine (withdrawal effects),CYP2D6 inhibitors (fluoxetine,paroxetine,bupropion),NSAIDs (may reduce antihypertensive effect),insulin/oral antidiabetics (masks hypoglycaemia),anaesthetics

Store below 25°C in a dry place, protected from moisture and light. Keep out of reach of children.

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