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Prescription requiredUnison PharmaceuticalsAnalgesic and anti-inflammatory and Analgesic and antipyretic

Akilos-SP Tablet

Aceclofenac (100mg) + Paracetamol (325mg) + Serratiopeptidase (15mg)

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Same composition, in stock now. Check with your doctor or pharmacist before you switch.

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Akilos-SP Tablet is used for akilos-SP Tablet is used for pain relief. It relieves pain in conditions like headache, mild migraine, musculoskeletal pain or painful menses.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Aceclofenac (100mg) + Paracetamol (325mg) + Serratiopeptidase (15mg)
Available variants: tablet 100mg + 325mg + 15mg 10`S
Best price: ₹46 (₹4.64 per tablet)
MRP: ₹49
Prescription: Required
Manufacturer: UNISON PHARMACEUTICALS

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Akilos-SP Tablet

Akilos-SP Tablet contains Aceclofenac (100mg) + Paracetamol (325mg) + Serratiopeptidase (15mg). It belongs to the Non-steroidal anti-inflammatory drug, Para-aminophenol derivative and Enzyme / disease-modifying anti-rheumatic agent class of medicines.

Uses of Akilos-SP Tablet

  • Akilos-SP Tablet is used for pain relief. It relieves pain in conditions like headache
  • mild migraine
  • musculoskeletal pain or painful menses.

Key benefits

  • Relieves pain and the swelling that causes it
  • Effective in arthritis and injury
  • The first choice for fever and everyday pain
  • Gentle on the stomach
  • unlike anti-inflammatory painkillers
  • Reduces swelling and joint damage over time
  • Improves function in inflammatory disease

How Akilos-SP Tablet works

Akilos-SP Tablet is a combination of three medicines: Aceclofenac, Paracetamol/Acetaminophen and Serratiopeptidase. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID), and Paracetamol/Acetaminophen is an antipyretic (fever reducer). They work by blocking the release of certain chemical messengers in the brain that cause pain and fever. Serratiopeptidase is an enzyme which works by breaking down abnormal proteins at the site of inflammation and promotes healing.

How to take Akilos-SP Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Akilos-SP Tablet is to be taken with food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause stomach bleeding, kidney failure, drowsiness and fits. It can cause severe and sometimes fatal liver damage, often with no symptoms at all for the first day. It can seriously suppress the bone marrow and damage the liver. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Akilos-SP Tablet

Most side effects of Akilos-SP are mild and settle as the body adjusts. Reported side effects include:

  • Nausea Vomiting Stomach pain Indigestion Heartburn Loss of appetite Diarrhea

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Akilos-SP Tablet

PregnancyAkilos-SP Tablet may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
BreastfeedingNo information is available on the use of Akilos-SP Tablet during lactation. Please consult your doctor.
AlcoholTaking Aceclofenac+Paracetamol/Acetaminophen+Serratiopeptidase with alcohol can cause liver damage.
DrivingMay cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
KidneyAkilos-SP Tablet should be used with caution in patients with kidney disease. Dose adjustment of Akilos-SP Tablet may be needed. Please consult your doctor.<br>Use of Akilos-SP Tablet is not recommended in patients with severe kidney disease.
LiverAkilos-SP Tablet should be used with caution in patients with liver disease. Dose adjustment of Akilos-SP Tablet may be needed. Please consult your doctor.<br>However, the use of Akilos-SP Tablet is not recommended in patients with severe liver disease and active liver disease.
Habit formingNo

Warnings and precautions

Take it with or just after food, and for the shortest time that works. Stop and seek urgent care for black or tarry stools, vomiting blood, or severe stomach pain — this group can cause bleeding from the stomach. Long or high-dose use raises the risk of heart attack, stroke and kidney injury, particularly in older people and those already at risk. Avoid if you are dehydrated or have an illness with vomiting or loose motions — the kidneys are vulnerable then. Must be avoided in the last three months of pregnancy. Never exceed the daily maximum printed on the pack. Paracetamol overdose damages the liver, and the damage can be silent for a day or two before it becomes serious. Check every other medicine you are taking. Paracetamol is in a very large number of cold, flu and pain combinations, and the doses add together. If you drink alcohol regularly, or have liver disease, ask your doctor what daily limit is safe for you. See a doctor if fever lasts more than three days, or pain more than five. Medicines that suppress the immune system need regular blood tests — do not miss them. Report fever, sore throat, mouth ulcers or unusual bruising promptly if you are on an immune-suppressing medicine. Tell your doctor about any infection, and before any vaccination. Methotrexate for arthritis is taken ONCE A WEEK. Taking it daily by mistake is dangerous — check the day on your pack.

Do not take Akilos-SP if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active stomach ulcer, severe kidney or heart failure, or asthma triggered by aspirin or anti-inflammatory painkillers. Not in the third trimester of pregnancy. Not for people with severe liver disease, except under medical supervision. Not for people with an active serious infection, or with severe liver or bone-marrow disease. Several of these medicines must not be used in pregnancy.

Interactions with other medicines

Combining with a blood thinner or aspirin sharply raises the bleeding risk. Reduces the effect of blood pressure medicines and water tablets, and together with them can harm the kidneys. Never take two anti-inflammatory painkillers at the same time. Regular alcohol use increases the risk of liver injury. Tell your doctor if you are on warfarin — regular high-dose paracetamol can affect it. Tell your doctor about all other medicines, especially anti-inflammatory painkillers and antibiotics. Live vaccines are generally avoided while on immune-suppressing treatment.

How to store Akilos-SP Tablet

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Akilos-SP Tablet

<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li>You have been prescribed this combination medicine for relieving pain and inflammation.</li> <li>Take it with food to avoid getting an upset stomach.</li> <li>It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how Akilos SP Tablet affects you.</li> <li>Avoid consuming alcohol when taking Akilos SP Tablet as it may cause excessive drowsiness and increase the risk of liver damage.</li> <li><div>Do not take it with any other medicine containing acetaminophen (drugs for pain/fever or cough-and-cold) without asking your doctor first. </div></li></ul></div></div></div></div></div></div>

Manufacturer and class

Manufacturer:
UNISON PHARMACEUTICALS
Therapeutic class:
Analgesic and anti-inflammatory and Analgesic and antipyretic
Drug class:
Non-steroidal anti-inflammatory drug, Para-aminophenol derivative and Enzyme / disease-modifying anti-rheumatic agent

Substitutes for Akilos-SP Tablet

Medicines with the same active ingredient (Aceclofenac (100mg) + Paracetamol (325mg) + Serratiopeptidase (15mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Akilos-SP Tablet
Velocist-P TabletRISNIK LIFE SCIENCE PVT LTDtablet · 10`S₹5213% more
Xypace TabletXYRIS LIFE SCIENCES PVT LTDtablet · 10`S₹5723% more
Aserra P TabletBIOCEUTICStablet · 10`S₹7154% more
Flexace-SP TabletAMNEAN THERAPEUTICStablet · 10`S₹7971% more
Ark SP TabletAPEX LABORATORIES LTD`tablet · 10`S₹8889% more
Neorelax SP TabletMEYER ORGANICS PVT LTDtablet · 10`S₹102119% more
Torpedo SP TabletWALFS PHARMAtablet · 10`S₹103121% more
Ashycloflam SP Tablet A/A1X10₹104123% more
Ebility Asp TabletAbbott Healthcare Pvt Ltdtablet · 10`S₹107130% more
Acemiz S Tablet1X10₹121160% more
Megaceclo SP Tablet1X10₹123164% more
Zerodol SP TabletIPCA LABORATORIES LTD`tablet · 10 Tablet₹126171% more
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Akilos-SP Tablet FAQs

What is Akilos-SP Tablet used for?
Akilos-SP Tablet is commonly used for Akilos-SP Tablet is used for pain relief. It relieves pain in conditions like headache, mild migraine, musculoskeletal pain or painful menses. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Akilos-SP Tablet?
Akilos-SP Tablet contains Aceclofenac (100mg) + Paracetamol (325mg) + Serratiopeptidase (15mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Akilos-SP Tablet?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Akilos-SP Tablet work?
Akilos-SP Tablet is a combination of three medicines: Aceclofenac, Paracetamol/Acetaminophen and Serratiopeptidase.
Is Akilos-SP Tablet a prescription medicine?
Yes. Akilos-SP Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Akilos-SP Tablet?
The side effects reported most often with Akilos-SP are Nausea Vomiting Stomach pain Indigestion Heartburn Loss of appetite Diarrhea. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Akilos-SP Tablet be taken during pregnancy?
Akilos-SP Tablet may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Akilos-SP.
Can I drink alcohol while taking Akilos-SP Tablet?
Taking Aceclofenac+Paracetamol/Acetaminophen+Serratiopeptidase with alcohol can cause liver damage.
What if I miss a dose of Akilos-SP Tablet?
Take it as soon as you remember.
Is Akilos-SP Tablet habit forming?
No. Akilos-SP Tablet is not known to be habit forming when taken as prescribed.
How much does Akilos-SP Tablet cost on PingMeDoc Pharmacy?
Akilos-SP Tablet starts at ₹46 (MRP ₹49) on PingMeDoc Pharmacy. Available in tablet 100mg + 325mg + 15mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Akilos-SP Tablet?
Akilos-SP Tablet is manufactured by UNISON PHARMACEUTICALS. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Akilos-SP Tablet delivered?
Akilos-SP Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Akilos-SP Tablet, Quick facts

Salt
Aceclofenac (100mg) + Paracetamol (325mg) + Serratiopeptidase (15mg)
Form
tablet
Best price
₹46 (₹4.64 per tablet)
MRP
₹49
Prescription
Required (Rx)
Schedule
Schedule H
Brand
UNISON PHARMACEUTICALS
Manufacturer
UNISON PHARMACEUTICALS
Therapeutic class
Analgesic and anti-inflammatory and Analgesic and antipyretic
Drug class
Non-steroidal anti-inflammatory drug, Para-aminophenol derivative and Enzyme / disease-modifying anti-rheumatic agent
Habit forming
No
Variants
tablet 100mg + 325mg + 15mg 10`S
Delivery
Standard across India

References

The information on Akilos-SP Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Akilos-SP Tablet.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.