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Prescription requiredAprica Healthcare

Apriglim M2

Glimepiride (2mg) + Metformin (500mg)

Apriglim M2 is used for apriglim-M 2 Tablet SR is used in the treatment of type 2 diabetes.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026

₹142
100% genuine medicinesPharmacist-verified orderDelivered across India

Key details

Salt: Glimepiride (2mg) + Metformin (500mg)
Available variants: NA 15`S
Best price: ₹142
Prescription: Required
Manufacturer: APRICA HEALTHCARE

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Apriglim M2

Apriglim M2 contains Glimepiride (2mg) + Metformin (500mg).

Uses of Apriglim M2

Apriglim-M 2 Tablet SR is used in the treatment of type 2 diabetes.

How Apriglim M2 works

Apriglim-M 2 Tablet SR is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.

How to take Apriglim M2

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Apriglim-M 2 Tablet SR is to be taken with food.<br>Apriglim-M 2 Tablet SR may cause stomach upset if taken empty stomach.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take the missed dose of Apriglim M2 as soon as you remember. If it is almost time for the next dose, skip the missed one and carry on with the usual schedule. Do not take two doses together to make up for a missed dose.

If you take too much

Taking more Apriglim M2 than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.

Side effects of Apriglim M2

Most side effects of Apriglim M2 are mild and settle as the body adjusts. Reported side effects include:

  • Hypoglycemia (low blood sugar level) Taste change Nausea Diarrhea Stomach pain Headache Upper respiratory tract infection

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Apriglim M2

PregnancyApriglim-M 2 Tablet SR may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
BreastfeedingApriglim-M 2 Tablet SR is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
AlcoholTaking metformin with alcohol can cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, sleepiness, stomach upset, or other unusual symptoms.
KidneyApriglim-M 2 Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Apriglim-M 2 Tablet SR may be needed. Please consult your doctor.<br>Use of Apriglim-M 2 Tablet SR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
LiverApriglim-M 2 Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Apriglim-M 2 Tablet SR may be needed. Please consult your doctor.<br>Apriglim-M 2 Tablet SR is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

Interactions with other medicines

Tell your doctor or pharmacist about every medicine you take, including over-the-counter products, vitamins and herbal or ayurvedic preparations, before starting Apriglim M2. Some combinations can change how Apriglim M2 works or raise the chance of side effects.

How to store Apriglim M2

Store Apriglim M2 below 30°C in a cool, dry place away from direct sunlight and moisture. Keep the pack tightly closed and out of the reach of children. Do not use it after the expiry date printed on the pack.

Expert advice for Apriglim M2

<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li><div>You have been prescribed this combination medicine as it can control blood sugar better than metformin alone.</div></li> <li>You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Apriglim M2 Tablet PR.</li> <li>Take it with food to lower your chance of having an upset stomach.</li> <li>Monitor your blood sugar level regularly while you are taking this medicine. </li> <li>Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.</li> <li>It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. </li> <li>Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Apriglim M2 Tablet PR may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.</li> <li>Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).</li></ul></div></div></div></div></div></div>

Manufacturer and class

Manufacturer:
APRICA HEALTHCARE

Substitutes for Apriglim M2

Medicines with the same active ingredient (Glimepiride (2mg) + Metformin (500mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Apriglim M2
Glitaray 1 mg TabletLLOYD HEALTHCAREtablet · 10`S₹3972% cheaper
Linpride-2BALINT PHARMA10`S₹4667% cheaper
Newmet Mv 0.2SRNOUVELLE PHARMACEUTICALS10`S₹5264% cheaper
Ozomet G2 TabletOZONE PHARMACEUTICALS LTDtablet · 15`S₹5561% cheaper
Glimiscore M 1CRESHA LIFESCIENCES10`S₹6157% cheaper
Glucobeat G2 Forte TabletSAAN LAB LLPtablet · 10`S₹6554% cheaper
Glimcare M2Q-CHECK14`S₹10129% cheaper
Gala-MG 1 TabletKINESIS PHARMACEUTICALS (P) LTD.`tablet · 10`S₹10228% cheaper
Startglim M2 TabletSANZ PHARMACEUTICALStablet · 15`S₹10625% cheaper
Gala-MG 2 TabletKINESIS PHARMACEUTICALS (P) LTD.`tablet · 10`S₹10724% cheaper
Humiglim 2 mg TabletVERSE LIFESCIENCEStablet · 30`S₹12015% cheaper
Humiglim M2 TabletVERSE LIFESCIENCEStablet · 15`S₹16013% more
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Apriglim M2 FAQs

What is Apriglim M2 used for?
Apriglim M2 is commonly used for Apriglim-M 2 Tablet SR is used in the treatment of type 2 diabetes. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Apriglim M2?
Apriglim M2 contains Glimepiride (2mg) + Metformin (500mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Apriglim M2?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Apriglim M2 work?
Apriglim-M 2 Tablet SR is a combination of two antidiabetic medicines: Glimepiride and Metformin.
Is Apriglim M2 a prescription medicine?
Yes. Apriglim M2 is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Apriglim M2?
The side effects reported most often with Apriglim M2 are Hypoglycemia (low blood sugar level) Taste change Nausea Diarrhea Stomach pain Headache Upper respiratory tract infection. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Apriglim M2 be taken during pregnancy?
Apriglim-M 2 Tablet SR may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Apriglim M2.
Can I drink alcohol while taking Apriglim M2?
Taking metformin with alcohol can cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, sleepiness, stomach upset, or other unusual symptoms.
What if I miss a dose of Apriglim M2?
Take the missed dose of Apriglim M2 as soon as you remember. If it is almost time for the next dose, skip the missed one and carry on with the usual schedule. Do not take two doses together to make up for a missed dose.
Is there a cheaper substitute for Apriglim M2?
Glitaray 1 mg Tablet has the same active ingredient and strength and is listed from ₹39 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Apriglim M2 cost on PingMeDoc Pharmacy?
Apriglim M2 starts at ₹142 on PingMeDoc Pharmacy. Available in NA 15`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Apriglim M2?
Apriglim M2 is manufactured by APRICA HEALTHCARE. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Apriglim M2 delivered?
Apriglim M2 is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Apriglim M2, Quick facts

Salt
Glimepiride (2mg) + Metformin (500mg)
Best price
₹142
Prescription
Required (Rx)
Schedule
Schedule H
Brand
APRICA HEALTHCARE
Manufacturer
APRICA HEALTHCARE
Variants
NA 15`S
Delivery
Standard across India

References

The information on Apriglim M2 is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  2. National List of Essential Medicines (NLEM) 2022, Government of India.
  3. Manufacturer's package insert / prescribing information for Apriglim M2.
  4. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

More from PingMeDoc™

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.