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Prescription requiredAprica HealthcareAnti-diabetic

Apriglim M2

Glimepiride (2mg) + Metformin (500mg)

Currently out of stock

Same composition, in stock now. Check with your doctor or pharmacist before you switch.

  • Linpride-2₹44View
  • Glimed Mf2 Tablet₹49View
  • Glidum-Mf2₹49View

Apriglim M2 is used for apriglim-M 2 Tablet SR is used in the treatment of type 2 diabetes.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated October 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Glimepiride (2mg) + Metformin (500mg)
Available variants: NA 15`S
Best price: ₹134
MRP: ₹142
Prescription: Required
Manufacturer: APRICA HEALTHCARE

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Apriglim M2

Apriglim M2 contains Glimepiride (2mg) + Metformin (500mg). It belongs to the Sulfonylurea and Biguanide class of medicines.

Uses of Apriglim M2

Apriglim-M 2 Tablet SR is used in the treatment of type 2 diabetes.

Benefits of Apriglim M2

In Type 2 diabetes
Apriglim M2 prompts your pancreas to release more insulin, bringing high sugar readings down quickly. Steady control lowers the long-term risk of damage to the eyes, kidneys, nerves and blood vessels.

How Apriglim M2 works

Apriglim-M 2 Tablet SR is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.

How to take Apriglim M2

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Apriglim-M 2 Tablet SR is to be taken with food.<br>Apriglim-M 2 Tablet SR may cause stomach upset if taken empty stomach.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Apriglim M2

Most side effects of Apriglim M2 are mild and settle as the body gets used to the medicine. The ones reported most often are:

  • Hypoglycemia (low blood sugar level) Taste change Nausea Diarrhea Stomach pain Headache Upper respiratory tract infection

Stop the medicine and get help at once for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Apriglim M2

Alcohol
Taking metformin with alcohol can cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, sleepiness, stomach upset, or other unusual symptoms.
PregnancyUNSAFE
Apriglim-M 2 Tablet SR may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Breast feedingSAFE
Apriglim-M 2 Tablet SR is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
DrivingCAUTION
May cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
KidneyUNSAFE
Apriglim-M 2 Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Apriglim-M 2 Tablet SR may be needed. Please consult your doctor.<br>Use of Apriglim-M 2 Tablet SR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
LiverUNSAFE
Apriglim-M 2 Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Apriglim-M 2 Tablet SR may be needed. Please consult your doctor.<br>Apriglim-M 2 Tablet SR is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

Warnings and precautions

If you feel shaky, sweaty, confused or unusually hungry, take sugar, glucose or a sweet drink at once and tell your doctor — these are signs your blood sugar has fallen too low. Do not skip meals while on this medicine — a missed meal is the commonest cause of a low-sugar episode. Carry glucose, sugar or sweets with you, and tell the people you live and work with what a low-sugar episode looks like. Older people and people with kidney trouble are more likely to have low sugar, and may need a smaller dose. Stomach upset is common in the first two weeks and usually settles; taking it with food helps. Tell your doctor before any surgery or a scan that uses contrast dye — this medicine is usually stopped for a short time around them. Stop and seek urgent care if you develop deep rapid breathing, severe weakness, muscle pain or vomiting with cold clammy skin. This is rare but serious. Long-term use can lower vitamin B12, so your doctor may check it from time to time.

Do not take Apriglim M2 if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.

Interactions with other medicines

Many medicines change how strongly this works — tell your doctor about aspirin, blood thinners, antifungals, sulfa antibiotics and beta blockers in particular. Beta blockers can mask the warning signs of low blood sugar. Tell your doctor about water tablets, steroids, and any contrast dye scan. Alcohol increases the risk of the rare acid build-up and should be limited.

How to store Apriglim M2

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Quick tips for Apriglim M2

  • Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).</li></ul></div></div></div></div></div></div>

People taking Apriglim M2 are often asked to check these from time to time. Your doctor decides which and how often.

Manufacturer and class

Manufacturer:
APRICA HEALTHCARE
Therapeutic class:
Anti-diabetic
Drug class:
Sulfonylurea and Biguanide

Substitutes for Apriglim M2

Medicines with the same active ingredient (Glimepiride (2mg) + Metformin (500mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Apriglim M2
Linpride-2BALINT PHARMA10`S₹4467% cheaper
Glimed Mf2 Tablet1X10₹4963% cheaper
Glidum-Mf21X10₹4963% cheaper
Ozomet G2 TabletOZONE PHARMACEUTICALS LTDtablet · 15`S₹5757% cheaper
Glucobeat G2 TabletSAAN LAB LLPtablet · 10`S₹5857% cheaper
Glucobeat G2 Forte TabletSAAN LAB LLPtablet · 10`S₹6154% cheaper
Biopride M2 TabletLIVIDUS PHARMACEUTICALS PVT LTD.`tablet · 10`S₹7346% cheaper
K-Glim M2Blue Cross Laboratories Pvt Ltd15`S₹7346% cheaper
Gala-MG 1 TabletKINESIS PHARMACEUTICALS (P) LTD.`tablet · 10`S₹9728% cheaper
Humiglim 2 mg TabletVERSE LIFESCIENCEStablet · 30`S₹11415% cheaper
Diapride M 1MICRO LABS15`S₹15213% more
Glimestar-M2 TabletMANKIND (PHARMA)tablet · 15`S₹16926% more
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Apriglim M2 FAQs

What is Apriglim M2 used for?
Apriglim M2 is commonly used for Apriglim-M 2 Tablet SR is used in the treatment of type 2 diabetes. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What are the benefits of Apriglim M2?
Type 2 diabetes: Apriglim M2 prompts your pancreas to release more insulin, bringing high sugar readings down quickly. Steady control lowers the long-term risk of damage to the eyes, kidneys, nerves and blood vessels.
What is the salt in Apriglim M2?
Apriglim M2 contains Glimepiride (2mg) + Metformin (500mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Apriglim M2?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Apriglim M2 work?
Apriglim-M 2 Tablet SR is a combination of two antidiabetic medicines: Glimepiride and Metformin.
Is Apriglim M2 a prescription medicine?
Yes. Apriglim M2 is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Apriglim M2?
The side effects reported most often with Apriglim M2 are Hypoglycemia (low blood sugar level) Taste change Nausea Diarrhea Stomach pain Headache Upper respiratory tract infection. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Apriglim M2 be taken during pregnancy?
Apriglim M2 is not recommended in pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Apriglim M2.
Can I drink alcohol while taking Apriglim M2?
Ask your doctor before drinking alcohol while on Apriglim M2.
What if I miss a dose of Apriglim M2?
Take it as soon as you remember.
Is Apriglim M2 habit forming?
No. Apriglim M2 is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Apriglim M2?
Linpride-2 has the same active ingredient and strength and is listed from ₹44 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Apriglim M2 cost on PingMeDoc Pharmacy?
Apriglim M2 starts at ₹134 (MRP ₹142) on PingMeDoc Pharmacy. Available in NA 15`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Apriglim M2?
Apriglim M2 is manufactured by APRICA HEALTHCARE. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Apriglim M2 delivered?
Apriglim M2 is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Apriglim M2, Quick facts

Salt
Glimepiride (2mg) + Metformin (500mg)
Best price
₹134
MRP
₹142
Prescription
Required (Rx)
Schedule
Schedule H
Brand
APRICA HEALTHCARE
Manufacturer
APRICA HEALTHCARE
Therapeutic class
Anti-diabetic
Drug class
Sulfonylurea and Biguanide
Habit forming
No
Variants
NA 15`S
Delivery
Standard across India

References

Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered pharmacist. It does not replace your own doctor's advice.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Apriglim M2.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.