Apriglim M1 Tab
Aprica Healthcare - Tablet - 15 S
Prescription required
Glimepiride (2mg) + Metformin (500mg)
Apriglim M2 is used for apriglim-M 2 Tablet SR is used in the treatment of type 2 diabetes.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026
Apriglim M2 contains Glimepiride (2mg) + Metformin (500mg).
Apriglim-M 2 Tablet SR is used in the treatment of type 2 diabetes.
Apriglim-M 2 Tablet SR is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Apriglim-M 2 Tablet SR is to be taken with food.<br>Apriglim-M 2 Tablet SR may cause stomach upset if taken empty stomach.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take the missed dose of Apriglim M2 as soon as you remember. If it is almost time for the next dose, skip the missed one and carry on with the usual schedule. Do not take two doses together to make up for a missed dose.
Taking more Apriglim M2 than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.
Most side effects of Apriglim M2 are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Apriglim-M 2 Tablet SR may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor. |
|---|---|
| Breastfeeding | Apriglim-M 2 Tablet SR is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby. |
| Alcohol | Taking metformin with alcohol can cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, sleepiness, stomach upset, or other unusual symptoms. |
| Kidney | Apriglim-M 2 Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Apriglim-M 2 Tablet SR may be needed. Please consult your doctor.<br>Use of Apriglim-M 2 Tablet SR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine. |
| Liver | Apriglim-M 2 Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Apriglim-M 2 Tablet SR may be needed. Please consult your doctor.<br>Apriglim-M 2 Tablet SR is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease. |
Tell your doctor or pharmacist about every medicine you take, including over-the-counter products, vitamins and herbal or ayurvedic preparations, before starting Apriglim M2. Some combinations can change how Apriglim M2 works or raise the chance of side effects.
Store Apriglim M2 below 30°C in a cool, dry place away from direct sunlight and moisture. Keep the pack tightly closed and out of the reach of children. Do not use it after the expiry date printed on the pack.
<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li><div>You have been prescribed this combination medicine as it can control blood sugar better than metformin alone.</div></li> <li>You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Apriglim M2 Tablet PR.</li> <li>Take it with food to lower your chance of having an upset stomach.</li> <li>Monitor your blood sugar level regularly while you are taking this medicine. </li> <li>Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.</li> <li>It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. </li> <li>Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Apriglim M2 Tablet PR may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.</li> <li>Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).</li></ul></div></div></div></div></div></div>
Medicines with the same active ingredient (Glimepiride (2mg) + Metformin (500mg)). Ask your doctor or pharmacist before switching brands.
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Aprica Healthcare - Tablet - 15 S
Prescription required
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The information on Apriglim M2 is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.