Azulix 3Mf Tablet

Composition of Azulix 3Mf Tablet

Azulix 3Mf Tablet contains Glimepiride 3 mg + Metformin hydrochloride 500 mg (modified/extended release) + Pioglitazone 15 mg. It belongs to the Sulfonylurea + Biguanide + Thiazolidinedione (TZD) class of medicines.

Uses of Azulix 3Mf Tablet

• Treatment of type 2 diabetes mellitus in adults when blood sugar is not adequately controlled with diet
• exercise and/or other antidiabetic medicines; helps control fasting and post‑meal glucose and improve insulin sensitivity.

Key benefits

• Lowers fasting and post-meal blood glucose
• Improves insulin sensitivity
• Helps achieve HbA1c control in type 2 diabetes
• Reduces insulin resistance-associated hyperglycaemia

How Azulix 3Mf Tablet works

Glimepiride (a sulfonylurea) increases insulin release from pancreatic beta cells. Metformin reduces hepatic glucose production and improves peripheral insulin sensitivity. Pioglitazone (a thiazolidinedione) improves insulin sensitivity in muscle and adipose tissue via PPAR‑γ activation.

How to take Azulix 3Mf Tablet

Oral tablet; take exactly as prescribed. Usually taken once daily with or immediately after food (often with breakfast) to reduce stomach upset and risk of low sugar; swallow whole (do not crush/chew if modified/extended release). Monitor blood glucose regularly.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. It may cause low blood sugar and marked stomach upset. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Azulix 3Mf Tablet

Most side effects of Azulix 3Mf are mild and settle as the body adjusts. Reported side effects include:

• Hypoglycaemia
• dizziness
• headache
• nausea
• diarrhoea
• abdominal pain
• metallic taste
• weight gain
• oedema (swelling)
• fatigue

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Azulix 3Mf Tablet

Warnings and precautions

Prescription only. Risk of hypoglycaemia (especially if meals are skipped, alcohol use, or with other antidiabetics); carry glucose. Metformin: risk of lactic acidosis—avoid in severe kidney impairment, severe liver disease, dehydration, sepsis, hypoxia; stop temporarily around major surgery or iodinated contrast as advised. Pioglitazone: may cause fluid retention/worsen heart failure; avoid in NYHA class III/IV heart failure; monitor for weight gain/oedema. Possible risk of fractures and rare bladder cancer—avoid in active bladder cancer/ unexplained hematuria. Monitor kidney function, liver enzymes, and blood glucose/HbA1c. Not for type 1 diabetes or diabetic ketoacidosis.

Do not take Azulix 3Mf if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis. Not for people with heart failure, active bladder cancer or unexplained blood in the urine.

Interactions with other medicines

Alcohol (increases hypoglycaemia and lactic acidosis risk), insulin or other sulfonylureas/meglitinides (hypoglycaemia), diuretics/corticosteroids/thyroid hormones (may raise glucose), beta-blockers (mask hypoglycaemia symptoms), ACE inhibitors (may enhance glucose-lowering), iodinated contrast media (lactic acidosis risk—hold metformin as advised), cimetidine (raises metformin levels), rifampicin (may reduce pioglitazone effect), gemfibrozil (increases pioglitazone levels)

How to store Azulix 3Mf Tablet

Store below 25°C in a dry place, protected from light and moisture. Keep in original blister/strip and out of reach of children.

Expert advice for Azulix 3Mf Tablet

Take it shortly before a meal, and eat that meal. Check your sugar as often as your doctor has asked, especially when your routine changes. Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them. Take it with the first mouthful of your meal so it can act on that meal. Expect some wind in the first weeks; it usually settles.

Manufacturer and class

Manufacturer:

TORRENT PHARMACEUTICALS

Therapeutic class:

Antidiabetic

Drug class:

Sulfonylurea + Biguanide + Thiazolidinedione (TZD)