Bendex 400 Tablet

Composition of Bendex 400 Tablet

Bendex 400 Tablet contains Albendazole (400mg). It belongs to the Benzimidazole anthelmintic class of medicines.

Uses of Bendex 400 Tablet

• Treatment of intestinal worm (helminth) infestations such as ascariasis (roundworm)
• hookworm infection
• trichuriasis (whipworm)
• enterobiasis (pinworm)
• strongyloidiasis and tapeworm infection; also used for certain tissue infections like neurocysticercosis and hydatid disease as prescribed

Key benefits

• Kills and removes intestinal worms
• Relieves symptoms like abdominal pain and diarrhea due to worms
• Broad-spectrum activity against common helminths
• Helps prevent complications of heavy worm infestation

How Bendex 400 Tablet works

Albendazole is a broad-spectrum anthelmintic. It inhibits microtubule formation and glucose uptake in worms, leading to energy depletion and death of the parasite.

How to take Bendex 400 Tablet

Take as directed by a physician. For deworming, it is commonly taken as a single 400 mg dose; some infections need repeat dosing. Preferably take with food (fatty meal improves absorption, especially for tissue infections); swallow tablet with water.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Bendex 400 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause vomiting, abdominal cramps and nerve symptoms. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Bendex 400 Tablet

Most side effects of Bendex are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• vomiting
• abdominal pain
• diarrhea
• headache
• dizziness
• temporary hair loss
• rash
• increased liver enzymes

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Bendex 400 Tablet

Warnings and precautions

Not recommended in pregnancy (especially 1st trimester); rule out pregnancy before therapy for prolonged/high-dose use. Use with caution in liver disease; liver function tests may be needed for longer courses. May cause bone marrow suppression rarely (watch for fever/sore throat/easy bruising) in prolonged therapy. Treating neurocysticercosis can worsen neurological symptoms due to inflammatory response; may require steroids/antiepileptics under medical supervision.

Do not take Bendex if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Several medicines in this group are avoided in early pregnancy.

Interactions with other medicines

Cimetidine, dexamethasone and praziquantel may increase albendazole levels; carbamazepine, phenytoin and phenobarbital may reduce effect; warfarin may have altered anticoagulant effect (monitor INR); ritonavir may affect levels

How to store Bendex 400 Tablet

Store below 25°C in a cool, dry place. Protect from moisture and direct sunlight. Keep out of reach of children.

Expert advice for Bendex 400 Tablet

Bendex 400 Tablet can be harmful to an unborn baby. Do not take it during pregnancy. Use birth control measures to prevent pregnancy while taking Bendex 400 Tablet. Your doctor may monitor your blood counts and liver function before you start taking this medicine and regularly throughout your treatment. Avoid being near people who are sick or have infections. Inform your doctor if you develop signs of infection. Do not skip doses and finish the prescribed course, even if you start to feel better. Stopping it early may increase your risk of further infection.

Manufacturer and class

Manufacturer:

CIPLA LIMITED

Therapeutic class:

Anthelmintic

Drug class:

Benzimidazole anthelmintic

Chemical class:

2- benzimidazolylcarbamic acid esters