
Advog 0.2
Eris Life Sciences Pvt Ltd - 10 S
Prescription required
Gliclazide 30 mg (modified release/extended release) + Metformin hydrochloride (extended release) (strength unknown)
Cyblex M 30 XR Tablet is used for type 2 diabetes mellitus (adult) to improve blood glucose control when diet and exercise alone are insufficient; used when combination therapy with a sulfonylurea and metformin is appropriate.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Cyblex M 30 XR Tablet contains Gliclazide 30 mg (modified release/extended release) + Metformin hydrochloride (extended release) (strength unknown). It belongs to the Sulfonylurea + Biguanide (extended-release combination) class of medicines.
Type 2 diabetes mellitus (adult) to improve blood glucose control when diet and exercise alone are insufficient; used when combination therapy with a sulfonylurea and metformin is appropriate.
Gliclazide (a sulfonylurea) stimulates the pancreas to release insulin, helping lower blood glucose. Metformin reduces glucose production in the liver and improves insulin sensitivity, reducing insulin resistance and lowering glucose absorption from the gut.
Take by mouth as advised by the doctor, usually once daily with or after food (preferably with breakfast) to reduce stomach upset. Swallow the XR tablet whole; do not crush, chew, or split. Monitor blood glucose regularly and follow diet/exercise advice.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Cyblex M are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Not recommended; consult doctor (insulin is generally preferred in pregnancy). |
|---|---|
| Breastfeeding | Consult your doctor before using this while breastfeeding. |
| Alcohol | Avoid |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Consult your doctor if you have kidney disease. |
| Liver | Consult your doctor if you have liver disease. |
| Habit forming | No |
Risk of hypoglycemia (especially if meals are skipped, with alcohol, or with other antidiabetics); carry a fast-acting sugar source. Metformin may rarely cause lactic acidosis—seek urgent care for fast breathing, severe weakness, abdominal pain, or unusual sleepiness; higher risk with kidney disease, dehydration, severe infection, heart/liver failure. Use caution/avoid in significant renal impairment; kidney function should be assessed before and during therapy. Stop temporarily before major surgery or iodinated contrast procedures as advised. Use caution in elderly, malnourished, and those with adrenal/pituitary insufficiency. Not for type 1 diabetes or diabetic ketoacidosis.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.
Alcohol (increases risk of hypoglycemia and lactic acidosis), iodinated contrast media, insulin/other antidiabetics (increased hypoglycemia), corticosteroids (may raise glucose), thiazide/loop diuretics (may raise glucose; dehydration risk), ACE inhibitors (may increase hypoglycemia), beta-blockers (mask hypoglycemia symptoms), fluoroquinolones (glucose disturbances), azole antifungals and macrolides (may increase sulfonylurea effect), cimetidine (may increase metformin levels)
Store below 25°C in a cool, dry place; protect from moisture and light; keep in original blister pack and out of reach of children.
Take it shortly before a meal, and eat that meal. Check your sugar as often as your doctor has asked, especially when your routine changes. Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them.

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The information on Cyblex M 30 XR Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.