Acecloren Tab
Indoco Remedies Ltd - Tablet - 10 S
Prescription required
Mefenamic Acid (250mg) + Dicyclomine (20mg)
Cyclomeff Tablet is used for cyclomeff 20 mg/250 mg Tablet is used in the treatment of menstrual pain and colicky pain. It relieves colicky pain associated with intestinal, biliary, and ureteric colic.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Cyclomeff Tablet contains Mefenamic Acid (250mg) + Dicyclomine (20mg). It belongs to the Non-steroidal anti-inflammatory drug and Antispasmodic class of medicines.
Cyclomeff 20 mg/250 mg Tablet is a combination of two medicines: Dicyclomine and Mefenamic Acid. Dicyclomine is an anticholinergic which works by relaxing the muscles in the stomach and gut (intestine). It stops sudden muscle contractions (spasms), thereby relieving cramps, pain, bloating, and discomfort. Mefenamic Acid is a non-steroidal anti-inflammatory drug (NSAID) which works by blocking the release of certain chemical messengers that cause abdominal pain and inflammation (swelling). Together, they relieve menstrual cramps and colicky pain.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cyclomeff 20 mg/250 mg Tablet is to be taken with food.<br>This will help to avoid stomach upset.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause stomach bleeding, kidney failure, drowsiness and fits. It can cause a racing heart, confusion, blurred vision and difficulty passing urine. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Cyclomeff are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Cyclomeff 20 mg/250 mg Tablet may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor. |
|---|---|
| Breastfeeding | Cyclomeff 20 mg/250 mg Tablet is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby. |
| Alcohol | Taking Mefenamic acid with alcohol increases the risk of stomach bleeding. |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Cyclomeff 20 mg/250 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Cyclomeff 20 mg/250 mg Tablet may be needed. Please consult your doctor.<br>Use of Cyclomeff 20 mg/250 mg Tablet is not recommended in patients with severe kidney disease. |
| Liver | Cyclomeff 20 mg/250 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Cyclomeff 20 mg/250 mg Tablet may be needed. Please consult your doctor. |
| Habit forming | No |
Take it with or just after food, and for the shortest time that works. Stop and seek urgent care for black or tarry stools, vomiting blood, or severe stomach pain — this group can cause bleeding from the stomach. Long or high-dose use raises the risk of heart attack, stroke and kidney injury, particularly in older people and those already at risk. Avoid if you are dehydrated or have an illness with vomiting or loose motions — the kidneys are vulnerable then. Must be avoided in the last three months of pregnancy. Severe abdominal pain, particularly with fever or vomiting, needs a doctor rather than a painkiller or antispasmodic. May cause blurred vision and drowsiness — do not drive until you know how it affects you. Tell your doctor if you have glaucoma, an enlarged prostate or difficulty passing urine.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active stomach ulcer, severe kidney or heart failure, or asthma triggered by aspirin or anti-inflammatory painkillers. Not in the third trimester of pregnancy. Not for people with glaucoma, urinary retention, or a blockage of the gut.
Combining with a blood thinner or aspirin sharply raises the bleeding risk. Reduces the effect of blood pressure medicines and water tablets, and together with them can harm the kidneys. Never take two anti-inflammatory painkillers at the same time. Adds to the dry mouth, constipation and drowsiness caused by antihistamines and some antidepressants.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Use the lowest dose for the shortest period. If you need a painkiller regularly, see your doctor rather than continuing on your own. Paracetamol is the safer choice for simple fever and headache. Take it when the cramps start rather than on a fixed schedule, unless your doctor has said otherwise. A warm compress and regular meals help cramping in irritable bowel syndrome.
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The information on Cyclomeff Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.