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Prescription requiredZydus Healthcare PharmaCough and cold preparation and Antidepressant

Dexbe Tablet

Dextromethorphan (45mg) + Bupropion (105mg)

₹137MRP ₹1445% offIn stock
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Delivered across India, usually 8–11 days after the order is confirmed. ₹49 delivery, free above ₹999.

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This medicine needs a prescription.

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Dexbe Tablet is used for this medicine is used in the treatment of cough, chest congestion, common cold symptoms, depression, anxiety, obsessive compulsive disorder, nerve pain and migraine prevention.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated October 2026

Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Dextromethorphan (45mg) + Bupropion (105mg)
Available variants: tablet 45mg + 105mg 10`S
Best price: ₹137 (₹13.72 per tablet)
MRP: ₹144
Prescription: Required
Manufacturer: ZYDUS HEALTHCARE PHARMA

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Same salt, lower price

Medicines with the same active ingredient and strength as Dexbe Tablet.

You are viewing

Dexbe Tablet

tablet - 45mg + 105mg - 10 S

₹137

₹13.72 per tablet

  • Auvelia Tab

    LUPIN LAB · tablet - 45mg + 105mg - 10 S · Rx

    ₹127

    ₹12.74 per tablet

Compare all substitutes
Same salt, different brand — what does that mean?

A substitute contains the same active ingredient (salt), in the same strength, as Dexbe Tablet. The medicine inside is the same — the brand name, manufacturer and price are what differ.

All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.

Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.

Composition of Dexbe Tablet

Dexbe Tablet contains Dextromethorphan (45mg) + Bupropion (105mg). It belongs to the Expectorant / mucolytic / bronchodilator and Antidepressant class of medicines.

Uses of Dexbe Tablet

  • Cough
  • Chest congestion
  • Common cold symptoms
  • Depression
  • Anxiety
  • Obsessive compulsive disorder
  • Nerve pain
  • Migraine prevention

Benefits of Dexbe Tablet

In Cough
Dexbe either loosens the mucus so a chesty cough clears it more easily, or settles the reflex behind a dry, tickly cough, depending on the type you have been given.
In Chest congestion
Dexbe thins thick mucus in the chest so it can be coughed up, easing the heaviness and rattling and helping you breathe more freely.
In Common cold symptoms
Dexbe relieves the blocked nose, cough and congestion of a cold so you can rest and get on with your day while the infection runs its course.
In Depression
Dexbe restores the balance of the brain's chemical messengers, gradually lifting mood, energy, sleep and appetite. The benefit builds over several weeks, which is why it is important to keep taking it.
In Anxiety
Dexbe calms persistent worry and the physical tension that goes with it, so that everyday situations feel manageable again.
In Obsessive compulsive disorder
Dexbe reduces the intrusive thoughts and the urge to repeat rituals, usually alongside talking therapy.
In Nerve pain
Dexbe dampens the pain signals from damaged nerves, easing burning, shooting or tingling pain that ordinary painkillers do not touch.
In Migraine prevention
Dexbe, taken every day, reduces how often migraines come and how severe they are. It does not treat an attack once it has started.

How Dexbe Tablet works

This medicine combines 2 active ingredients: Dextromethorphan and Bupropion. Dextromethorphan loosens and thins the mucus in your airways so a cough clears it more easily, and eases the tightness that comes with congestion. Bupropion restores the balance of the chemical messengers in the brain that regulate mood, sleep and the way pain is felt.

How to take Dexbe Tablet

Swallow the tablet whole with a glass of water. Do not chew, crush or break it unless your doctor has told you to. Take it with or after food. Taking it at about the same time each day helps you remember. Follow the dose and the duration written on your prescription.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause vomiting, severe drowsiness, a racing heart and, with codeine, dangerously slow breathing. It can cause fits, dangerous heart rhythm disturbance and coma, and is particularly dangerous with the older tricyclic medicines. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Dexbe Tablet

Most side effects of Dexbe are mild and settle as the body gets used to the medicine. The ones reported most often are:

  • Nausea
  • Vomiting
  • Stomach upset
  • Drowsiness
  • Tremor
  • Fast heartbeat
  • Dry mouth
  • Drowsiness or difficulty sleeping
  • Headache
  • Weight change
  • Reduced sexual desire
  • Constipation

Stop the medicine and get help at once for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Dexbe Tablet

AlcoholUNSAFE
Do not drink alcohol while taking this medicine.
PregnancyCONSULT YOUR DOCTOR
Consult your doctor before using this in pregnancy.
Breast feedingCONSULT YOUR DOCTOR
Consult your doctor before using this while breastfeeding.
DrivingCAUTION
May cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
KidneyCAUTION
Use with caution if you have kidney disease. Your doctor may adjust the dose or monitor your kidney function.
LiverCONSULT YOUR DOCTOR
Consult your doctor if you have liver disease.

Warnings and precautions

See a doctor if a cough lasts more than a week, or comes with fever, breathlessness, chest pain or blood in the sputum. Do not give cough and cold preparations to young children except on a doctor's advice. Do not combine two cough preparations — they frequently contain the same ingredients, and the doses add up. Preparations containing codeine can cause dependence and must be used only for the period your doctor specifies. These medicines take two to four weeks to begin working, and longer for the full effect. Stopping at two weeks because nothing has changed is the commonest mistake. Never stop suddenly. Abrupt withdrawal causes dizziness, electric-shock sensations, irritability and flu-like symptoms — your doctor will reduce the dose gradually. Tell your doctor or go to hospital immediately if thoughts of harming yourself appear or worsen, particularly in the first weeks or after a dose change, and especially in anyone under twenty-five. Seek urgent care for agitation with fever, shivering, a racing heart, muscle twitching or confusion, particularly if more than one medicine affecting serotonin is being taken. Side effects are usually worst in the first fortnight and then settle.

Do not take Dexbe if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Codeine-containing preparations are not for children, or for anyone with breathing difficulty. Must not be combined with a monoamine oxidase inhibitor, or started within the gap your doctor specifies after one.

Interactions with other medicines

Sedating ingredients add to the effect of alcohol and sleeping tablets. Decongestants such as phenylephrine and pseudoephedrine can raise blood pressure — tell your doctor if you are hypertensive. Tramadol, triptans for migraine, linezolid, St John's wort and other antidepressants can together raise serotonin dangerously. Anti-inflammatory painkillers and blood thinners increase the bleeding risk when combined with this group.

How to store Dexbe Tablet

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Quick tips for Dexbe Tablet

  • Drink plenty of water.
  • It thins mucus better than any syrup.
  • Steam inhalation helps congestion and costs nothing.
  • Measure the dose with the cup supplied.
  • Give it a fair trial of several weeks, and keep your review appointments.
  • Take it at the same time each day.
  • At night if it makes you drowsy, in the morning if it disturbs sleep.
  • Talking therapy alongside medicine works better than either alone for most people.

Manufacturer and class

Manufacturer:
ZYDUS HEALTHCARE PHARMA
Therapeutic class:
Cough and cold preparation and Antidepressant
Drug class:
Expectorant / mucolytic / bronchodilator and Antidepressant

Substitutes for Dexbe Tablet

Medicines with the same active ingredient (Dextromethorphan (45mg) + Bupropion (105mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Dexbe Tablet
Auvelia TabletLUPIN LABtablet · 10`S₹1277% cheaper
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Dexbe Tablet FAQs

What is Dexbe Tablet used for?
Dexbe Tablet is commonly used for cough, chest congestion, common cold symptoms, depression, anxiety, obsessive compulsive disorder, nerve pain and migraine prevention. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What are the benefits of Dexbe Tablet?
Cough: Dexbe either loosens the mucus so a chesty cough clears it more easily, or settles the reflex behind a dry, tickly cough, depending on the type you have been given. It is also used for chest congestion, common cold symptoms, depression.
What is the salt in Dexbe Tablet?
Dexbe Tablet contains Dextromethorphan (45mg) + Bupropion (105mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Dexbe Tablet?
Swallow the tablet whole with a glass of water. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Dexbe Tablet work?
This medicine combines 2 active ingredients: Dextromethorphan and Bupropion.
Is Dexbe Tablet a prescription medicine?
Yes. Dexbe Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Dexbe Tablet?
The side effects reported most often with Dexbe are Nausea, Vomiting, Stomach upset, Drowsiness, Tremor. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Dexbe Tablet be taken during pregnancy?
Consult your doctor before taking Dexbe Tablet in pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Dexbe.
Can I drink alcohol while taking Dexbe Tablet?
No. Do not drink alcohol while taking Dexbe Tablet.
What if I miss a dose of Dexbe Tablet?
Take it as soon as you remember.
Is Dexbe Tablet habit forming?
No. Dexbe Tablet is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Dexbe Tablet?
Auvelia Tablet has the same active ingredient and strength and is listed from ₹127 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Dexbe Tablet cost on PingMeDoc Pharmacy?
Dexbe Tablet starts at ₹137 (MRP ₹144) on PingMeDoc Pharmacy. Available in tablet 45mg + 105mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Dexbe Tablet?
Dexbe Tablet is manufactured by ZYDUS HEALTHCARE PHARMA. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Dexbe Tablet delivered?
Dexbe Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Dexbe Tablet, Quick facts

Salt
Dextromethorphan (45mg) + Bupropion (105mg)
Form
tablet
Best price
₹137 (₹13.72 per tablet)
MRP
₹144
Prescription
Required (Rx)
Schedule
Schedule H
Brand
ZYDUS HEALTHCARE PHARMA
Manufacturer
ZYDUS HEALTHCARE PHARMA
Therapeutic class
Cough and cold preparation and Antidepressant
Drug class
Expectorant / mucolytic / bronchodilator and Antidepressant
Habit forming
No
Variants
tablet 45mg + 105mg 10`S
Delivery
Standard across India

References

Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered pharmacist. It does not replace your own doctor's advice.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Dexbe Tablet.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.