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Prescription requiredLarenonAnti-emetic and Analgesic and anti-inflammatory
Domoxen-250 Tablet
Domperidone (10mg) + Naproxen (250mg)
₹81MRP ₹855% offIn stock
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Domoxen-250 Tablet is used for this medicine is used in the treatment of nausea, vomiting, bloating, slow stomach emptying, pain, inflammation, arthritis, fever and period pain.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated October 2026
Licensed pharmacyPharmacist-verified orderDelivered across India
Key details
Salt: Domperidone (10mg) + Naproxen (250mg)
Available variants: tablet 10mg + 250mg 10`S
Best price: ₹81 (₹8.08 per tablet)
MRP: ₹85
Prescription: Required
Manufacturer: LARENON
Ordering notes
Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy
Same salt, lower price
Medicines with the same active ingredient and strength as Domoxen-250 Tablet.
You are viewing
Domoxen-250 Tablet
tablet - 10mg + 250mg - 10 S
₹81
₹8.08 per tablet
- Quickrel 10/250 Tab
Dr Reddys Laboratories Ltd · tablet - 250mg + 10mg - 10 S · Rx
₹73
₹7.35 per tablet
- Napcox D 250MG Tab
MEXICAN WAVE PHARMA · tablet - 250 mg - 10 S · Rx
₹78
₹7.84 per tablet
Same salt, different brand — what does that mean?
A substitute contains the same active ingredient (salt), in the same strength, as Domoxen-250 Tablet. The medicine inside is the same — the brand name, manufacturer and price are what differ.
All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.
Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.
Composition of Domoxen-250 Tablet
Domoxen-250 Tablet contains Domperidone (10mg) + Naproxen (250mg). It belongs to the Anti-emetic / prokinetic and Non-steroidal anti-inflammatory drug class of medicines.
Uses of Domoxen-250 Tablet
- Nausea
- Vomiting
- Bloating
- Slow stomach emptying
- Pain
- Inflammation
- Arthritis
- Fever
- Period pain
Benefits of Domoxen-250 Tablet
- In Nausea
- Domoxen-250 blocks the signals to the brain's vomiting centre, settling the nausea of illness, travel, surgery or chemotherapy.
- In Vomiting
- Domoxen-250 stops vomiting so that fluids and other medicines stay down, preventing the dehydration that repeated vomiting causes.
- In Bloating
- Domoxen-250 helps the stomach empty more quickly, easing the bloating and early fullness that follow a meal.
- In Slow stomach emptying
- Domoxen-250 strengthens the stomach's movements so food passes through more normally, relieving nausea, fullness and reflux.
- In Pain
- Domoxen-250 blocks the chemicals that cause pain at the site of an injury or inflammation, giving relief that is often stronger than paracetamol for pain with swelling.
- In Inflammation
- Domoxen-250 reduces the swelling, redness, heat and stiffness of an inflamed joint or injured tissue, so movement is easier.
- In Arthritis
- Domoxen-250 eases the pain and morning stiffness of arthritis, so joints move more freely and daily tasks become easier.
- In Fever
- Domoxen-250 lowers a raised temperature and relieves the aching that goes with it.
- In Period pain
- Domoxen-250 reduces the chemicals that make the womb cramp during a period, which is why it works well for period pain when taken as the pain begins.
How Domoxen-250 Tablet works
This medicine combines 2 active ingredients: Domperidone and Naproxen. Domperidone settles the stomach and blocks the signals that trigger nausea and vomiting, and helps the stomach empty at a normal rate. Naproxen blocks the chemicals your body makes at a site of injury or inflammation, which reduces pain, swelling and fever.
How to take Domoxen-250 Tablet
Swallow the tablet whole with a glass of water. Do not chew, crush or break it unless your doctor has told you to. Take it 15 to 30 minutes before meals. Taking it at about the same time each day helps you remember. Follow the dose and the duration written on your prescription.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Missed dose and overdose
If you miss a dose
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
If you take too much
An overdose of this medicine can cause drowsiness, disorientation and abnormal muscle movements. It can cause stomach bleeding, kidney failure, drowsiness and fits. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Side effects of Domoxen-250 Tablet
Most side effects of Domoxen-250 are mild and settle as the body gets used to the medicine. The ones reported most often are:
- Dry mouth
- Drowsiness
- Headache
- Loose motions
- Restlessness
- Indigestion
- Stomach pain
- Nausea
- Heartburn
- Dizziness
- Swelling of the ankles and feet
Stop the medicine and get help at once for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
Safety advice for Domoxen-250 Tablet
- AlcoholUNSAFE
- Do not drink alcohol while taking this medicine.
- PregnancyUNSAFE
- Not recommended in pregnancy. It may harm the developing baby, so tell your doctor at once if you are or might be pregnant.
- Breast feedingCONSULT YOUR DOCTOR
- Consult your doctor before using this while breastfeeding.
- DrivingCAUTION
- May cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
- KidneyCONSULT YOUR DOCTOR
- Consult your doctor if you have kidney disease.
- LiverCONSULT YOUR DOCTOR
- Consult your doctor if you have liver disease.
Warnings and precautions
Use it for the shortest period that works. These medicines are not intended for long-term daily use. Report any unusual muscle stiffness, tremor, restlessness or uncontrolled movements of the face or limbs at once — stop and contact your doctor. Tell your doctor if you have a heart rhythm problem; some of this group affect the heart's electrical timing. Persistent vomiting needs a diagnosis. Do not keep suppressing it without seeing a doctor, especially with abdominal pain, fever or blood. Take it with or just after food, and for the shortest time that works. Stop and seek urgent care for black or tarry stools, vomiting blood, or severe stomach pain — this group can cause bleeding from the stomach. Long or high-dose use raises the risk of heart attack, stroke and kidney injury, particularly in older people and those already at risk. Avoid if you are dehydrated or have an illness with vomiting or loose motions — the kidneys are vulnerable then. Must be avoided in the last three months of pregnancy.
Do not take Domoxen-250 if
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with bleeding, blockage or perforation of the gut, or with certain heart rhythm disorders. Not for people with an active stomach ulcer, severe kidney or heart failure, or asthma triggered by aspirin or anti-inflammatory painkillers. Not in the third trimester of pregnancy.
Interactions with other medicines
Antifungals, some antibiotics and heart-rhythm medicines increase the risk of rhythm problems when combined. Adds to the drowsiness of alcohol and sedatives. Combining with a blood thinner or aspirin sharply raises the bleeding risk. Reduces the effect of blood pressure medicines and water tablets, and together with them can harm the kidneys. Never take two anti-inflammatory painkillers at the same time.
How to store Domoxen-250 Tablet
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Quick tips for Domoxen-250 Tablet
- Take it shortly before meals for bloating and early fullness.
- Sip fluids frequently in small amounts, and use oral rehydration salts if you have been vomiting.
- Use the lowest dose for the shortest period.
- If you need a painkiller regularly, see your doctor rather than continuing on your own.
- Paracetamol is the safer choice for simple fever and headache.
Related lab tests
People taking Domoxen-250 are often asked to check these from time to time. Your doctor decides which and how often.
Manufacturer and class
- Manufacturer:
- LARENON
- Therapeutic class:
- Anti-emetic and Analgesic and anti-inflammatory
- Drug class:
- Anti-emetic / prokinetic and Non-steroidal anti-inflammatory drug
Substitutes for Domoxen-250 Tablet
Medicines with the same active ingredient (Domperidone (10mg) + Naproxen (250mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Domoxen-250 Tablet |
|---|---|---|---|
| Quickrel 10/250 TabletDr Reddys Laboratories Ltd | tablet · 10`S | ₹73 | 9% cheaper |
| Napcox D 250 mg TabletMEXICAN WAVE PHARMA | tablet · 10`S | ₹78 | 3% cheaper |
| Naprozen D 250 Tablet | 1X10 | ₹100 | 24% more |
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Domoxen-250 Tablet FAQs
What is Domoxen-250 Tablet used for?
Domoxen-250 Tablet is commonly used for nausea, vomiting, bloating, slow stomach emptying, pain, inflammation, arthritis, fever and period pain. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What are the benefits of Domoxen-250 Tablet?
Nausea: Domoxen-250 blocks the signals to the brain's vomiting centre, settling the nausea of illness, travel, surgery or chemotherapy. It is also used for vomiting, bloating, slow stomach emptying.
What is the salt in Domoxen-250 Tablet?
Domoxen-250 Tablet contains Domperidone (10mg) + Naproxen (250mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Domoxen-250 Tablet?
Swallow the tablet whole with a glass of water. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Domoxen-250 Tablet work?
This medicine combines 2 active ingredients: Domperidone and Naproxen.
Is Domoxen-250 Tablet a prescription medicine?
Yes. Domoxen-250 Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Domoxen-250 Tablet?
The side effects reported most often with Domoxen-250 are Dry mouth, Drowsiness, Headache, Loose motions, Restlessness. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Domoxen-250 Tablet be taken during pregnancy?
Domoxen-250 Tablet is not recommended in pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Domoxen-250.
Can I drink alcohol while taking Domoxen-250 Tablet?
No. Do not drink alcohol while taking Domoxen-250 Tablet.
What if I miss a dose of Domoxen-250 Tablet?
Take it as soon as you remember.
Is Domoxen-250 Tablet habit forming?
No. Domoxen-250 Tablet is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Domoxen-250 Tablet?
Quickrel 10/250 Tablet has the same active ingredient and strength and is listed from ₹73 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Domoxen-250 Tablet cost on PingMeDoc Pharmacy?
Domoxen-250 Tablet starts at ₹81 (MRP ₹85) on PingMeDoc Pharmacy. Available in tablet 10mg + 250mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Domoxen-250 Tablet?
Domoxen-250 Tablet is manufactured by LARENON. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Domoxen-250 Tablet delivered?
Domoxen-250 Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.
Domoxen-250 Tablet, Quick facts
- Salt
- Domperidone (10mg) + Naproxen (250mg)
- Form
- tablet
- Best price
- ₹81 (₹8.08 per tablet)
- MRP
- ₹85
- Prescription
- Required (Rx)
- Schedule
- Schedule H
- Brand
- LARENON
- Manufacturer
- LARENON
- Therapeutic class
- Anti-emetic and Analgesic and anti-inflammatory
- Drug class
- Anti-emetic / prokinetic and Non-steroidal anti-inflammatory drug
- Habit forming
- No
- Variants
- tablet 10mg + 250mg 10`S
- Delivery
- Standard across India
References
Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered pharmacist. It does not replace your own doctor's advice.
- PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
- CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
- Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
- National List of Essential Medicines (NLEM) 2022, Government of India.
- Manufacturer's package insert / prescribing information for Domoxen-250 Tablet.
- World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.
Next steps
Safety disclaimer
Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.