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Dr Reddys Laboratories Ltd - Tablet - 100mg + 325mg + 65mg - 10 S
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Naproxen (250mg) + Domperidone (10mg)
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Quickrel 10/250 Tablet is used for prevention of Migraine.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Quickrel 10/250 Tablet contains Naproxen (250mg) + Domperidone (10mg). It belongs to the Non-steroidal anti-inflammatory drug and Anti-emetic / prokinetic class of medicines.
Prevention of Migraine
Quickrel 250mg/10mg Tablet is a combination of two medicines: naproxen and domperidone. Naproxen is a non-steroidal anti-inflammatory drug (NSAID) that works by blocking the release of certain chemical messengers that cause migraine pain. Domperidone works on the part of the brain that controls nausea and vomiting associated with migraine. Together, these medicines help relieve migraine symptoms.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Quickrel 250mg/10mg Tablet may be taken with or without food.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you miss a dose of Quickrel 250mg/10mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
An overdose of this medicine can cause stomach bleeding, kidney failure, drowsiness and fits. It can cause drowsiness, disorientation and abnormal muscle movements. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Quickrel 10/250 are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Pregnancy CONSULT YOUR DOCTOR |
|---|---|
| Breastfeeding | Breast feeding CAUTION |
| Alcohol | Alcohol UNSAFE |
| Driving | Driving UNSAFE |
| Kidney | Kidney CAUTION |
| Liver | Liver UNSAFE |
| Habit forming | No |
Take it with or just after food, and for the shortest time that works. Stop and seek urgent care for black or tarry stools, vomiting blood, or severe stomach pain — this group can cause bleeding from the stomach. Long or high-dose use raises the risk of heart attack, stroke and kidney injury, particularly in older people and those already at risk. Avoid if you are dehydrated or have an illness with vomiting or loose motions — the kidneys are vulnerable then. Must be avoided in the last three months of pregnancy. Use it for the shortest period that works. These medicines are not intended for long-term daily use. Report any unusual muscle stiffness, tremor, restlessness or uncontrolled movements of the face or limbs at once — stop and contact your doctor. Tell your doctor if you have a heart rhythm problem; some of this group affect the heart's electrical timing. Persistent vomiting needs a diagnosis. Do not keep suppressing it without seeing a doctor, especially with abdominal pain, fever or blood.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active stomach ulcer, severe kidney or heart failure, or asthma triggered by aspirin or anti-inflammatory painkillers. Not in the third trimester of pregnancy. Not for people with bleeding, blockage or perforation of the gut, or with certain heart rhythm disorders.
Combining with a blood thinner or aspirin sharply raises the bleeding risk. Reduces the effect of blood pressure medicines and water tablets, and together with them can harm the kidneys. Never take two anti-inflammatory painkillers at the same time. Antifungals, some antibiotics and heart-rhythm medicines increase the risk of rhythm problems when combined. Adds to the drowsiness of alcohol and sedatives.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Take Quickrel 250mg/10mg Tablet exactly as prescribed. Do not take more than the recommended dose. Avoid alcohol while taking Quickrel 250mg/10mg Tablet, as it may increase dizziness and the risk of stomach bleeding. Quickrel 250mg/10mg Tablet may cause dizziness, so avoid driving or operating machinery until you know how it affects you. Do not take Quickrel 250mg/10mg Tablet with other NSAID painkillers unless advised by your doctor. Inform your doctor if you have a history of stomach ulcers, acid reflux, heart disease, kidney disease, asthma, or high blood pressure. Stop taking Quickrel 250mg/10mg Tablet and seek urgent medical help if you have black stools, vomit blood, severe stomach pain, chest pain, or swelling of the face or lips. Seek medical advice if you experience palpitations, fainting, or severe dizziness, as domperidone may affect heart rhythm in some people. Stay well hydrated and eat light meals if you experience nausea. Avoid common migraine triggers such as bright light, loud noise, missed meals, alcohol, and foods that can trigger your headaches. Consult your doctor if headaches become frequent or severe despite using Quickrel 250mg/10mg Tablet.
Medicines with the same active ingredient (Naproxen (250mg) + Domperidone (10mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Quickrel 10/250 Tablet |
|---|---|---|---|
| Napcox D 250 mg TabletMEXICAN WAVE PHARMA | tablet · 10`S | ₹78 | 7% more |
| Domoxen-250 TabletLARENON | tablet · 10`S | ₹81 | 10% more |
| Naprozen D 250 Tablet | 1X10 | ₹100 | 36% more |

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The information on Quickrel 10/250 Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.