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Glimigrand M2 Tablet

Glimepiride 2 mg + Metformin Hydrochloride 500 mg (SR/PR)

₹137MRP ₹1445% offIn stock
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Delivered across India in about 3–5 days, Chennai next day. ₹49 delivery, free above ₹999.

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Glimigrand M2 Tablet is used for type 2 diabetes mellitus (adult) when diet and exercise alone or single therapy is inadequate; helps control high blood sugar.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Glimepiride 2 mg + Metformin Hydrochloride 500 mg (SR/PR)
Available variants: tablet 2mg + 500mg 15`S
Best price: ₹137 (₹9.12 per tablet)
MRP: ₹144
Prescription: Required
Manufacturer: D EARTH PHARMACEUTICALS

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Same salt, lower price

Medicines with the same active ingredient and strength as Glimigrand M2 Tablet.

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Glimigrand M2 Tablet

tablet - 2mg + 500mg - 15 S

₹137

₹9.12 per tablet

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Compare all substitutes
Same salt, different brand — what does that mean?

A substitute contains the same active ingredient (salt), in the same strength, as Glimigrand M2 Tablet. The medicine inside is the same — the brand name, manufacturer and price are what differ.

All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.

Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.

Composition of Glimigrand M2 Tablet

Glimigrand M2 Tablet contains Glimepiride 2 mg + Metformin Hydrochloride 500 mg (SR/PR). It belongs to the Sulfonylurea + Biguanide class of medicines.

Uses of Glimigrand M2 Tablet

Type 2 diabetes mellitus (adult) when diet and exercise alone or single therapy is inadequate; helps control high blood sugar

Key benefits

  • Lowers fasting and post-meal blood glucose
  • Improves insulin sensitivity and reduces hepatic glucose output
  • Helps achieve better HbA1c control
  • May reduce diabetes-related complications with good control

How Glimigrand M2 Tablet works

Glimepiride (a sulfonylurea) stimulates the pancreas to release insulin and improves the body’s response to insulin. Metformin (a biguanide) reduces glucose production in the liver and decreases intestinal absorption of glucose while improving insulin sensitivity.

How to take Glimigrand M2 Tablet

Take orally as prescribed, usually once daily with breakfast or the first main meal. Swallow the tablet whole (especially if SR/PR); do not crush or chew. Monitor blood glucose regularly and follow diet/exercise advice.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Glimigrand M2 Tablet

Most side effects of Glimigrand M2 are mild and settle as the body adjusts. Reported side effects include:

  • Hypoglycaemia
  • dizziness
  • headache
  • nausea
  • diarrhoea
  • abdominal discomfort
  • metallic taste
  • decreased appetite
  • weight gain (with sulfonylurea)

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Glimigrand M2 Tablet

PregnancyNot recommended; consult doctor (insulin is usually preferred in pregnancy)
BreastfeedingConsult your doctor before using this while breastfeeding.
AlcoholAvoid
DrivingMay cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
KidneyConsult your doctor if you have kidney disease.
LiverConsult your doctor if you have liver disease.
Habit formingNo

Warnings and precautions

Risk of hypoglycaemia (especially with missed meals, alcohol, strenuous exercise, elderly, or kidney/liver impairment); lactic acidosis risk with metformin (more likely in severe kidney disease, dehydration, severe infection, shock, alcohol misuse). Contraindicated in severe renal impairment; assess kidney function before and during therapy. Temporarily stop metformin before/after iodinated contrast procedures and major surgery as advised. Use caution in hepatic impairment and in patients with heart failure. Seek urgent care for symptoms of low sugar or lactic acidosis (unusual tiredness, muscle pain, rapid breathing, abdominal pain).

Do not take Glimigrand M2 if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.

Interactions with other medicines

Alcohol (increases hypoglycaemia and lactic acidosis risk), insulin/other antidiabetics (additive hypoglycaemia), corticosteroids and thiazide diuretics (may raise glucose), beta-blockers (may mask hypoglycaemia symptoms), ACE inhibitors (may enhance glucose-lowering), quinolones (may alter glucose), rifampicin (may reduce sulfonylurea effect), azole antifungals/macrolides (may increase glimepiride effect), iodinated contrast media (increases lactic acidosis risk with metformin)

How to store Glimigrand M2 Tablet

Store below 25°C in a cool, dry place. Protect from moisture and direct light. Keep out of reach of children.

Expert advice for Glimigrand M2 Tablet

Take it shortly before a meal, and eat that meal. Check your sugar as often as your doctor has asked, especially when your routine changes. Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them.

Manufacturer and class

Manufacturer:
D EARTH PHARMACEUTICALS
Therapeutic class:
Antidiabetic
Drug class:
Sulfonylurea + Biguanide

Substitutes for Glimigrand M2 Tablet

Medicines with the same active ingredient (Glimepiride 2 mg + Metformin Hydrochloride 500 mg (SR/PR)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Glimigrand M2 Tablet
Glimefort-M2 TabletDRS CHOICE PHARMACEUTICALStablet · 10`S₹5957% cheaper
Glimefort-M2 Pro TabletDRS CHOICE PHARMACEUTICALStablet · 10`S₹8041% cheaper
Glimiact M2 TabletMIRTH PHARMACEUTICALStablet · 10`S₹9531% cheaper
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Glimigrand M2 Tablet FAQs

What is Glimigrand M2 Tablet used for?
Glimigrand M2 Tablet is commonly used for Type 2 diabetes mellitus (adult) when diet and exercise alone or single therapy is inadequate; helps control high blood sugar. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Glimigrand M2 Tablet?
Glimigrand M2 Tablet contains Glimepiride 2 mg + Metformin Hydrochloride 500 mg (SR/PR). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Glimigrand M2 Tablet?
Take orally as prescribed, usually once daily with breakfast or the first main meal. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Glimigrand M2 Tablet work?
Glimepiride (a sulfonylurea) stimulates the pancreas to release insulin and improves the body’s response to insulin.
Is Glimigrand M2 Tablet a prescription medicine?
Yes. Glimigrand M2 Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Glimigrand M2 Tablet?
The side effects reported most often with Glimigrand M2 are Hypoglycaemia, dizziness, headache, nausea, diarrhoea. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Glimigrand M2 Tablet be taken during pregnancy?
Not recommended; consult doctor (insulin is usually preferred in pregnancy) Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Glimigrand M2.
Can I drink alcohol while taking Glimigrand M2 Tablet?
Avoid
What if I miss a dose of Glimigrand M2 Tablet?
Take it as soon as you remember.
Is Glimigrand M2 Tablet habit forming?
No. Glimigrand M2 Tablet is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Glimigrand M2 Tablet?
Glimefort-M2 Tablet has the same active ingredient and strength and is listed from ₹59 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Glimigrand M2 Tablet cost on PingMeDoc Pharmacy?
Glimigrand M2 Tablet starts at ₹137 (MRP ₹144) on PingMeDoc Pharmacy. Available in tablet 2mg + 500mg 15`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Glimigrand M2 Tablet?
Glimigrand M2 Tablet is manufactured by D EARTH PHARMACEUTICALS. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Glimigrand M2 Tablet delivered?
Glimigrand M2 Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Glimigrand M2 Tablet, Quick facts

Salt
Glimepiride 2 mg + Metformin Hydrochloride 500 mg (SR/PR)
Form
tablet
Best price
₹137 (₹9.12 per tablet)
MRP
₹144
Prescription
Required (Rx)
Schedule
Schedule H
Brand
D EARTH PHARMACEUTICALS
Manufacturer
D EARTH PHARMACEUTICALS
Therapeutic class
Antidiabetic
Drug class
Sulfonylurea + Biguanide
Habit forming
No
Variants
tablet 2mg + 500mg 15`S
Delivery
Standard across India

References

Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.

  1. Manufacturer labeling, established medical literature, standard clinical guidelines for type 2 diabetes
  2. Indian Pharmacopoeia/approved drug monographs
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Glimigrand M2 Tablet.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.