Gmp 2

Composition of Gmp 2

Gmp 2 contains Glimepiride (2mg) + Metformin (500mg) + Pioglitazone (15mg). It belongs to the Sulfonylurea, Biguanide and Oral anti-diabetic class of medicines.

Uses of Gmp 2

Treatment of Type 2 diabetes mellitus

Key benefits

• In Treatment of Type 2 diabetes mellitus Type 2 diabetes is a condition where the body either does not produce enough insulin or cannot use it properly
• leading to high blood sugar levels. Gmp 2 Tablet SR helps improve blood sugar control by supporting better use of insulin and reducing excess glucose levels in the body. It helps maintain more stable sugar levels throughout the day
• lowers the risk of diabetes-related complications
• and supports overall metabolic health when used along with a proper diet and lifestyle.

How Gmp 2 works

Gmp 2 Tablet SR is a combination of three antidiabetic medicines: Glimepiride, Metformin and Pioglitazone. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide. It works by lowering glucose production in the liver, reducing glucose absorption from the intestines, and increasing the body's sensitivity to insulin. Pioglitazone is a thiazolidinedione, which further increases insulin sensitivity.

How to take Gmp 2

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Gmp 2 Tablet SR should be taken with or after food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Gmp 2 Tablet SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. It may cause low blood sugar and marked stomach upset. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Gmp 2

Most side effects of Gmp are mild and settle as the body adjusts. Reported side effects include:

• Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Gmp 2

Warnings and precautions

If you feel shaky, sweaty, confused or unusually hungry, take sugar, glucose or a sweet drink at once and tell your doctor — these are signs your blood sugar has fallen too low. Do not skip meals while on this medicine — a missed meal is the commonest cause of a low-sugar episode. Carry glucose, sugar or sweets with you, and tell the people you live and work with what a low-sugar episode looks like. Older people and people with kidney trouble are more likely to have low sugar, and may need a smaller dose. Stomach upset is common in the first two weeks and usually settles; taking it with food helps. Tell your doctor before any surgery or a scan that uses contrast dye — this medicine is usually stopped for a short time around them. Stop and seek urgent care if you develop deep rapid breathing, severe weakness, muscle pain or vomiting with cold clammy skin. This is rare but serious. Long-term use can lower vitamin B12, so your doctor may check it from time to time. If a low-sugar episode happens while on an alpha-glucosidase inhibitor such as voglibose or acarbose, use glucose — ordinary sugar and sweets work more slowly. Tell your doctor about any new swelling of the ankles, breathlessness or sudden weight gain.

Do not take Gmp if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis. Not for people with heart failure, active bladder cancer or unexplained blood in the urine.

Interactions with other medicines

Many medicines change how strongly this works — tell your doctor about aspirin, blood thinners, antifungals, sulfa antibiotics and beta blockers in particular. Beta blockers can mask the warning signs of low blood sugar. Tell your doctor about water tablets, steroids, and any contrast dye scan. Alcohol increases the risk of the rare acid build-up and should be limited. Low blood sugar is more likely when combined with insulin or a sulfonylurea.

How to store Gmp 2

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Gmp 2

Take it with food to lower your chance of having an upset stomach. It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor, and anxiety. Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Manufacturer and class

Manufacturer:

ARETAEUS PHARMACEUTICALS`

Therapeutic class:

ANTI DIABETIC

Drug class:

Sulfonylurea, Biguanide and Oral anti-diabetic