
Antoxipan Ds Sachet
Abbott India Limited - Sachet - 6 G
Human Insulin (40IU/ml)
Human Mixtard 50 Injection is used for treatment of diabetes mellitus (type 1 and type 2) requiring insulin to control blood glucose levels.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Human Mixtard 50 Injection contains Human Insulin (40IU/ml). It belongs to the Insulin (premixed human insulin: regular + NPH) class of medicines.
Treatment of diabetes mellitus (type 1 and type 2) requiring insulin to control blood glucose levels
This is a premixed insulin containing short-acting regular insulin for mealtime glucose control and intermediate-acting NPH insulin for longer basal control. It lowers blood glucose by increasing glucose uptake in muscle and fat and reducing glucose production by the liver.
For subcutaneous injection only, as prescribed by the doctor. Usually injected 30 minutes before meals; dosing and timing are individualized based on blood glucose. Rotate injection sites (abdomen, thigh, upper arm); do not massage the site. Do not use if the suspension is not uniformly milky after gentle rolling.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Contact your doctor or diabetes nurse for advice — do not take a double dose to make up for a missed injection.
An overdose of this medicine can cause severe low blood sugar, leading to fits or unconsciousness — this is a medical emergency. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Human Mixtard are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Generally safe (use under medical supervision; dose adjustments may be required) |
|---|---|
| Breastfeeding | Human Mixtard 50 Injection 40IU/ml is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby. |
| Alcohol | Use with caution (can increase risk of hypoglycaemia) |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Human Mixtard 50 Injection 40IU/ml should be used with caution in patients with kidney disease. Dose adjustment of Human Mixtard 50 Injection 40IU/ml may be needed. Please consult your doctor.<br>Regular monitoring of blood glucose levels is recommended for dose adjustment. |
| Liver | Human Mixtard 50 Injection 40IU/ml should be used with caution in patients with liver disease. Dose adjustment of Human Mixtard 50 Injection 40IU/ml may be needed. Please consult your doctor.<br>Regular monitoring of glucose levels is recommended for dose adjustment. |
| Habit forming | No |
Risk of hypoglycaemia—carry glucose/sugar and monitor blood glucose regularly. Do not use during episodes of hypoglycaemia. Dose adjustments may be needed with changes in diet, activity, illness, stress, kidney or liver disease. Use caution while driving/operating machinery if prone to low sugar. Injection must be subcutaneous; avoid intravenous use. Rotate sites to reduce lipodystrophy. Seek urgent help for severe allergy or severe hypoglycaemia.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not to be used during an episode of low blood sugar.
Other antidiabetics,ACE inhibitors (e.g., enalapril),beta-blockers (may mask hypoglycaemia),corticosteroids (e.g., prednisolone),thiazide diuretics,thyroid hormones,sympathomimetics (e.g., salbutamol),MAO inhibitors,alcohol
Store refrigerated at 2–8°C; do not freeze. Protect from light. After opening/in-use, store as per label instructions (often below 25–30°C) and use within the recommended period; keep away from heat and direct sunlight.
Keep an unopened supply in the fridge and the pen in use at room temperature, away from direct sunlight. Always carry a fast-acting sugar source. Check your sugar as your doctor has instructed, and keep a record to take to appointments.

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The information on Human Mixtard 50 Injection is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.