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Intas Pharmaceuticals Ltd - Tablet - 250mg - 10 S
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Metformin (500mg) + Pioglitazone (15mg) + Sitagliptin (100mg)
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Same composition, in stock now. Check with your doctor or pharmacist before you switch.
Ignalis Mp 500 is used for treatment of Type 2 diabetes mellitus.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Ignalis Mp 500 contains Metformin (500mg) + Pioglitazone (15mg) + Sitagliptin (100mg). It belongs to the Biguanide, Oral anti-diabetic and DPP-4 inhibitor class of medicines.
Treatment of Type 2 diabetes mellitus
Ignalis MP 500 Tablet SR is a combination of three antidiabetic medications. Metformin decreases the amount of glucose you absorb from your food and the glucose made by the liver. It also increases the body's response to insulin, a natural substance that controls the amount of glucose in the blood (blood sugar levels). Pioglitazone works by enhancing cellular responsiveness to insulin and increasing insulin-dependent glucose utilization and disposal. Sitagliptin helps to control blood sugar levels by increasing substances (incretins) in the body that make the pancreas release more insulin. It also signals the liver to stop producing sugar (glucose) when there is too much sugar in the blood.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ignalis MP 500 Tablet SR may be taken with or without food.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you miss a dose of Ignalis MP 500 Tablet SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
An overdose of this medicine can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. It may cause low blood sugar and marked stomach upset. It may cause low blood sugar, particularly if you also take other diabetes medicines. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Ignalis Mp are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Pregnancy UNSAFE |
|---|---|
| Breastfeeding | Breast feeding UNSAFE |
| Alcohol | Alcohol UNSAFE |
| Driving | Driving CONSULT YOUR DOCTOR |
| Kidney | Kidney CAUTION |
| Liver | Liver UNSAFE |
| Habit forming | No |
Stomach upset is common in the first two weeks and usually settles; taking it with food helps. Tell your doctor before any surgery or a scan that uses contrast dye — this medicine is usually stopped for a short time around them. Stop and seek urgent care if you develop deep rapid breathing, severe weakness, muscle pain or vomiting with cold clammy skin. This is rare but serious. Long-term use can lower vitamin B12, so your doctor may check it from time to time. If you feel shaky, sweaty, confused or unusually hungry, take sugar, glucose or a sweet drink at once and tell your doctor — these are signs your blood sugar has fallen too low. If a low-sugar episode happens while on an alpha-glucosidase inhibitor such as voglibose or acarbose, use glucose — ordinary sugar and sweets work more slowly. Tell your doctor about any new swelling of the ankles, breathlessness or sudden weight gain. Stop and see a doctor urgently if you get severe, persistent abdominal pain that spreads to your back, with or without vomiting. Tell your doctor if you develop severe or disabling joint pain. Blisters or peeling of the skin should be reported promptly.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with heart failure, active bladder cancer or unexplained blood in the urine.
Tell your doctor about water tablets, steroids, and any contrast dye scan. Alcohol increases the risk of the rare acid build-up and should be limited. Low blood sugar is more likely when combined with insulin or a sulfonylurea. Low blood sugar is more likely when this is combined with a sulfonylurea or insulin; your doctor may lower that dose.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Prefer taking Ignalis MP 500 Tablet SR after a meal or with a snack, as this will reduce the chance of an upset stomach. Ignalis MP 500 Tablet SR may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Always carry some sugary food or fruit juice with you in case you experience hypoglycemia (low blood sugar) symptoms, such as fatigue, dizziness, cold sweats, tremor, and anxiety. If you get unusually thirsty, pass urine more frequently, and feel tired, let your doctor know. These are signs that there is too much sugar in your blood and your dose may need adjusting. Monitor your blood sugar regularly while taking this medicine. Lifestyle changes like low sugar diet, exercising, losing weight, not smoking, and cutting down on alcohol intake may help this medication work better.
Medicines with the same active ingredient (Metformin (500mg) + Pioglitazone (15mg) + Sitagliptin (100mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Ignalis Mp 500 |
|---|---|---|---|
| Sitazit-Trio 500 mg TabletGLENMARK PHARMACEUTICALS | tablet · 10`S | ₹153 | 1% more |
| Sitaverse Mp Forte TabletVERSE LIFESCIENCES | tablet · 10`S | ₹164 | 9% more |
| Zita Pio Met 500 TabletGLENMARK PHARMACEUTICALS | tablet · 10`S | ₹174 | 15% more |
| Glura Mp 500 TabletERIS LIFE SCIENCES PVT LTD | tablet · 10`S | ₹182 | 21% more |
| Sitadoc Mp 500 TabletElbrit LIfe Sciences | tablet · 15`S | ₹214 | 42% more |

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The information on Ignalis Mp 500 is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.