Skip to main content
PingMeDoc
Prescription requiredIntas Pharmaceuticals LtdHORMONES

Lethyrox 25

Thyroxine (25mcg)

Lethyrox 25 is used for hypothyroidism.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

₹162MRP ₹1705% off
Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Thyroxine (25mcg)
Available variants: NA 120`S
Best price: ₹162
MRP: ₹170
Prescription: Required
Manufacturer: INTAS PHARMACEUTICALS`

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Lethyrox 25

Lethyrox 25 contains Thyroxine (25mcg). It belongs to the Thyroid hormone replacement class of medicines.

Uses of Lethyrox 25

Hypothyroidism

Key benefits

  • In Hypothyroidism LETHYrox 25 Tablet is used to treat hypothyroidism by restoring normal levels of thyroid hormone in the body. It helps improve energy levels
  • metabolism
  • mood
  • and other body functions that may be affected by an underactive thyroid gland.

How Lethyrox 25 works

LETHYrox 25 Tablet is a synthetic version of a hormone produced by the thyroid gland. It works by replacing the thyroid hormones that your thyroid gland cannot produce in a sufficient quantity, and relieves the symptoms of hypothyroidism (tiredness, weight gain, and depression).

How to take Lethyrox 25

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. LETHYrox 25 Tablet is to be taken on an empty stomach.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of LETHYrox 25 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause a racing heart, chest pain, tremor, fever and dangerous heart rhythm disturbance. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Lethyrox 25

Most side effects of Lethyrox are mild and settle as the body adjusts. Reported side effects include:

  • Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Lethyrox 25

PregnancyPregnancy SAFE IF PRESCRIBED
BreastfeedingBreast feeding SAFE IF PRESCRIBED
AlcoholAlcohol CONSULT YOUR DOCTOR
DrivingDriving SAFE
KidneyKidney SAFE IF PRESCRIBED
LiverLiver CONSULT YOUR DOCTOR
Habit formingNo

Warnings and precautions

Take it on an empty stomach, first thing in the morning, with water, and wait at least half an hour to an hour before eating or drinking anything else. Food, tea and coffee substantially reduce how much is absorbed. Separate it by at least four hours from calcium, iron, antacids and multivitamins — these bind it and block absorption. This is usually lifelong treatment. Do not stop when your reports come back normal; the normal report is the medicine working. Report palpitations, tremor, marked weight loss or difficulty sleeping — these suggest the dose is too high. Tell your doctor if you become pregnant; the requirement usually rises and needs prompt adjustment.

Do not take Lethyrox if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an untreated overactive thyroid or untreated adrenal insufficiency.

Interactions with other medicines

Calcium, iron, antacids, multivitamins and some cholesterol medicines block absorption — separate them by four hours. Tell your doctor if you take a blood thinner or diabetes medicine; doses may need review.

How to store Lethyrox 25

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Lethyrox 25

LETHYrox 25 Tablet should be taken on an empty stomach (ideally, first thing in the morning). No food, milk, or tea should be taken 1 hour before and 2 hours after taking this medicine. It may take 6 to 8 weeks to get the full effect. For most people, LETHYrox 25 Tablet can be a lifelong medication. Do not discontinue it without discussing your doctor. Inform your doctor if you have diarrhea, nervousness, irritability, sleep disturbances, shaking hands, or chest pain. Your doctor may adjust your dose. Leave a gap of at least 4 hours before taking any antacids, calcium or iron supplements, and multivitamins, as these may interfere with the effect of the medicine. Get your hormone levels checked regularly and inform your doctor if you notice a significant change in your body weight. The dose may need to be adjusted. Inform your doctor before changing the brand of LETHYrox 25 Tablet as all brands may not have the same effect.

Manufacturer and class

Manufacturer:
INTAS PHARMACEUTICALS`
Therapeutic class:
HORMONES
Drug class:
Thyroid hormone replacement
Chemical class:
Phenylalanine derivative

Substitutes for Lethyrox 25

Medicines with the same active ingredient (Thyroxine (25mcg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Lethyrox 25
Euthyrox 25 mg TabletMerck Ltdtablet · 100`S₹1479% cheaper
Thyroup 25LUPIN LAB120`S₹17810% more
Thyroup 12.5 mg TabletLUPIN LABtablet · 120`S₹18012% more
See all substitutes and alternatives

More from Intas Pharmaceuticals Ltd

View categories
Abione Tab
5% offRx

Abione Tab

Intas Pharmaceuticals Ltd - Tablet - 250mg - 10 S

₹26,891₹28,306

Save ₹1415

Prescription required

Actoid 10MG Cap
5% offRx

Actoid 10MG Cap

Intas Pharmaceuticals Ltd - Capsule - 10 mg - 10 S

₹347₹366

Save ₹19

Prescription required

Actoid 25MG Cap
5% offRx

Actoid 25MG Cap

Intas Pharmaceuticals Ltd - Capsule - 25 mg - 10 S

₹618₹650

Save ₹32

Prescription required

5% offRx

Adilip 135 Tab

Intas Pharmaceuticals Ltd - Tablet - 135mg - 10 S

₹262₹276

Save ₹14

Prescription required

5% offRx

Adilip 45 Tab

Intas Pharmaceuticals Ltd - Tablet - 45mg - 10 S

₹115₹121

Save ₹6

Prescription required

5% offRx

Alfa-Gpc

Intas Pharmaceuticals Ltd - 10 S

₹895₹942

Save ₹47

Prescription required

Allegix Lotion
5% off

Allegix Lotion

Intas Pharmaceuticals Ltd - Lotion - 100 ml

₹342₹360

Save ₹18

5% offRx

Altispor 200MG Cap

Intas Pharmaceuticals Ltd - Capsule - 200 mg - 10 S

₹224₹236

Save ₹12

Prescription required

More in Thyroid

View categories
Caricom Tab
5% offRx

Caricom Tab

Comed Chemicals - Tablet - 15 S

₹387₹408

Save ₹21

Prescription required

Com-D3 Strong Cap
5% offRx

Com-D3 Strong Cap

Comed Chemicals - Capsule - 1500mcg + 50mg + 0.25mcg + 7.5mg + 45mcg + 1250mg + 800mcg - 10 S

₹244₹257

Save ₹13

Prescription required

Cortimax Sus
Rx

Cortimax Sus

Zuventus Healthcare Ltd - 30 ml

₹91₹95

Save ₹4

Prescription required

Desowen Lotion
5% offRx

Desowen Lotion

Galderma India Pvt Ltd - Lotion - 0.05%W/W - 30 ml

₹276₹291

Save ₹15

Prescription required

Dobecure Cream
5% offRx

Dobecure Cream

Walfs Pharma - Cream - 5%W/W + 0.25%W/W + 0.25%W/W + 3%W/W - 30 G

₹128₹135

Save ₹7

Prescription required

Dronis-P 4MG Tab
5% offRx

Dronis-P 4MG Tab

Sun Pharma - Tablet - 4 mg - 24 S

₹456₹480

Save ₹24

Prescription required

5% offRx

Eglucent Mix 25 Kwikpen

Lupin Lab - 3 ml

₹1,416₹1,490

Save ₹74

Prescription required

Essendo-E2 Tab
5% offRx

Essendo-E2 Tab

Olympus - Tablet - 2mg - 28 S

₹355₹374

Save ₹19

Prescription required

Popular on PingMeDoc Pharmacy

View categories
Preloxetin 75/20 Cap
5% offRxOut of stock

Preloxetin 75/20 Cap

V Aid Biotech - Capsule - 10 S

₹178₹187

Save ₹9

Prescription required

Xylocaine 10% Spray
5% offRx

Xylocaine 10% Spray

German Remedies - Spray - 10%W/V - 50 ml

₹621₹654

Save ₹33

Prescription required

Amintoz Tab
5% offRxOut of stock

Amintoz Tab

Linux Laboratories - Tablet - 100mg - 10 S

₹41₹43

Save ₹2

Prescription required

5% offRxOut of stock

Telekast 10MG Tab 10S

Lupin Lab - Tablet - 10 mg - 10 S

₹167₹176

Save ₹9

Prescription required

Lirafit Injection (Pen)
5% offRx

Lirafit Injection (Pen)

Glenmark Pharmaceuticals - Injection - 1 S

₹1,982₹2,086

Save ₹104

Prescription required

5% offRxOut of stock

Testoki Tab

Uni-Sankyo - Tablet - 40mg - 10 S

₹284₹298

Save ₹14

Prescription required

Mypen 2
5% offOut of stock

Mypen 2

Wockhardt Ltd - 1 S

₹712₹749

Save ₹37

5% offRxOut of stock

Glisen Mf 1MG Tab

Alembic Pharma - Tablet - 1 mg - 15 S

₹204₹215

Save ₹11

Prescription required

Lethyrox 25 FAQs

What is Lethyrox 25 used for?
Lethyrox 25 is commonly used for Hypothyroidism. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Lethyrox 25?
Lethyrox 25 contains Thyroxine (25mcg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Lethyrox 25?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Lethyrox 25 work?
LETHYrox 25 Tablet is a synthetic version of a hormone produced by the thyroid gland.
Is Lethyrox 25 a prescription medicine?
Yes. Lethyrox 25 is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Lethyrox 25?
The side effects reported most often with Lethyrox are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Lethyrox 25 be taken during pregnancy?
Pregnancy SAFE IF PRESCRIBED Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Lethyrox.
Can I drink alcohol while taking Lethyrox 25?
Alcohol CONSULT YOUR DOCTOR
What if I miss a dose of Lethyrox 25?
If you miss a dose of LETHYrox 25 Tablet, take it as soon as possible.
Is Lethyrox 25 habit forming?
No. Lethyrox 25 is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Lethyrox 25?
Euthyrox 25 mg Tablet has the same active ingredient and strength and is listed from ₹147 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Lethyrox 25 cost on PingMeDoc Pharmacy?
Lethyrox 25 starts at ₹162 (MRP ₹170) on PingMeDoc Pharmacy. Available in NA 120`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Lethyrox 25?
Lethyrox 25 is manufactured by INTAS PHARMACEUTICALS`. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Lethyrox 25 delivered?
Lethyrox 25 is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Lethyrox 25, Quick facts

Salt
Thyroxine (25mcg)
Best price
₹162
MRP
₹170
Prescription
Required (Rx)
Schedule
Schedule H
Brand
Intas Pharmaceuticals Ltd
Manufacturer
INTAS PHARMACEUTICALS`
Therapeutic class
HORMONES
Drug class
Thyroid hormone replacement
Chemical class
Phenylalanine derivative
Action class
Thyroid Hormones
Habit forming
No
Variants
NA 120`S
Delivery
Standard across India

References

The information on Lethyrox 25 is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Lethyrox 25.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.