Liz-M

Composition of Liz-M

Liz-M contains Gliclazide (80mg) + Metformin (500mg). It belongs to the Sulfonylurea and Biguanide class of medicines.

Uses of Liz-M

Type 2 diabetes mellitus

Key benefits

• In Type 2 diabetes mellitus Type 2 diabetes is a condition where the body either does not make enough insulin or cannot use it properly
• leading to high blood sugar levels. Liz-M Tablet SR helps manage this condition and brings blood sugar under control. This medicine reduces the risk of complications such as nerve damage
• kidney problems
• and vision issues. Better sugar control
• it also supports overall health and improves the quality of life in people living with diabetes.

How Liz-M works

Liz-M Tablet SR is a combination of gliclazide and metformin. Gliclazide stimulates the pancreas to release more insulin, which helps lower the amount of glucose in the blood after meals. At the same time, Metformin reduces the production of glucose in the liver and improves the body’s response to insulin, allowing glucose to be utilized more efficiently by the muscles and other tissues. Together, they help maintain stable blood sugar levels throughout the day.

How to take Liz-M

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Liz-M Tablet SR should be taken with or after food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Liz-M Tablet SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Liz-M

Most side effects of Liz-M are mild and settle as the body adjusts. Reported side effects include:

• Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Liz-M

Warnings and precautions

If you feel shaky, sweaty, confused or unusually hungry, take sugar, glucose or a sweet drink at once and tell your doctor — these are signs your blood sugar has fallen too low. Do not skip meals while on this medicine — a missed meal is the commonest cause of a low-sugar episode. Carry glucose, sugar or sweets with you, and tell the people you live and work with what a low-sugar episode looks like. Older people and people with kidney trouble are more likely to have low sugar, and may need a smaller dose. Stomach upset is common in the first two weeks and usually settles; taking it with food helps. Tell your doctor before any surgery or a scan that uses contrast dye — this medicine is usually stopped for a short time around them. Stop and seek urgent care if you develop deep rapid breathing, severe weakness, muscle pain or vomiting with cold clammy skin. This is rare but serious. Long-term use can lower vitamin B12, so your doctor may check it from time to time.

Do not take Liz-M if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.

Interactions with other medicines

Many medicines change how strongly this works — tell your doctor about aspirin, blood thinners, antifungals, sulfa antibiotics and beta blockers in particular. Beta blockers can mask the warning signs of low blood sugar. Tell your doctor about water tablets, steroids, and any contrast dye scan. Alcohol increases the risk of the rare acid build-up and should be limited.

How to store Liz-M

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Liz-M

Monitor your blood sugar level regularly while you are taking this medicine. It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Liz-M Tablet SR may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood. Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice). Monitor your blood sugar level regularly while you are taking this medicine. It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Liz-M Tablet SR may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood. Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Manufacturer and class

Manufacturer:

DEY'S MEDICAL STORES MFD LTD`.

Therapeutic class:

ANTI DIABETIC

Drug class:

Sulfonylurea and Biguanide