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Prescription requiredMacleods Pharmaceuticals Pvt LtdCough and cold preparation

Macphylline Syrup

Acebrophylline (100mg)

Macphylline Syrup is used for macphylline Capsule is used in the treatment of chronic obstructive pulmonary disease.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

₹159₹1.59 per ml
Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Acebrophylline (100mg)
Available variants: syrup syrup 100ML
Best price: ₹159 (₹1.59 per ml)
Prescription: Required
Manufacturer: MACLEODS PHARMACEUTICALS LTD

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Macphylline Syrup

Macphylline Syrup contains Acebrophylline (100mg). It belongs to the Expectorant / mucolytic / bronchodilator class of medicines.

Uses of Macphylline Syrup

Macphylline Capsule is used in the treatment of chronic obstructive pulmonary disease.

Key benefits

  • Eases a chesty cough
  • Helps clear congestion

How Macphylline Syrup works

Macphylline Capsule is a mucolytic and bronchodilator. It works by relaxing the muscles of the airways and also thins and loosens mucus, making it easier to breathe.

How to take Macphylline Syrup

Take this medicine in the dose and duration as advised by your doctor. Macphylline Capsule is to be taken with food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause vomiting, severe drowsiness, a racing heart and, with codeine, dangerously slow breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Macphylline Syrup

Most side effects of Macphylline are mild and settle as the body adjusts. Reported side effects include:

  • Nausea
  • Vomiting
  • Stomach upset
  • Drowsiness
  • Tremor
  • Fast heartbeat

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Macphylline Syrup

PregnancyInformation regarding the use of Macphylline Capsule during pregnancy is not available. Please consult your doctor.
BreastfeedingInformation regarding the use of Macphylline Capsule during breastfeeding is not available. Please consult your doctor.
AlcoholMacphylline Capsule may cause excessive drowsiness with alcohol.
DrivingMay cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
KidneyMacphylline Capsule should be used with caution in patients with kidney disease. Dose adjustment of Macphylline Capsule may be needed. Please consult your doctor.
LiverMacphylline Capsule should be used with caution in patients with liver disease. Dose adjustment of Macphylline Capsule may be needed. Please consult your doctor.
Habit formingNo

Warnings and precautions

See a doctor if a cough lasts more than a week, or comes with fever, breathlessness, chest pain or blood in the sputum. Do not give cough and cold preparations to young children except on a doctor's advice. Do not combine two cough preparations — they frequently contain the same ingredients, and the doses add up. Preparations containing codeine can cause dependence and must be used only for the period your doctor specifies.

Do not take Macphylline if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Codeine-containing preparations are not for children, or for anyone with breathing difficulty.

Interactions with other medicines

Sedating ingredients add to the effect of alcohol and sleeping tablets. Decongestants such as phenylephrine and pseudoephedrine can raise blood pressure — tell your doctor if you are hypertensive.

How to store Macphylline Syrup

Store below 30°C, away from direct sunlight. Do not freeze. Once opened, use it within the period printed on the pack. Keep out of the reach of children.

Expert advice for Macphylline Syrup

<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li>You have been prescribed Macphylline Capsule for prevention and treatment of asthma and chronic obstructive pulmonary disease (COPD).</li> <li><div>It should be taken at the same time each day, preferably in the evening after food.</div></li> <li>It does not work right away and should not be used to relieve sudden breathing problems. Always keep a fast-acting (rescue) inhaler with you.</li> <li>Your doctor may take regular blood test to monitor potassium level and the level of this medicine in your body.</li> <li><div>Notify your doctor if you have ever been diagnosed with kidney, liver or heart disease, or if you have a smoking history. Your dose may need to be adjusted.</div></li> <li>Do not discontinue use without consulting your doctor, even if you feel better.</li></ul></div></div></div></div></div></div>

Manufacturer and class

Manufacturer:
MACLEODS PHARMACEUTICALS LTD
Therapeutic class:
Cough and cold preparation
Drug class:
Expectorant / mucolytic / bronchodilator

Substitutes for Macphylline Syrup

Medicines with the same active ingredient (Acebrophylline (100mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Macphylline Syrup
Brace-100ICARUS HEALTHCARE10`S₹10733% cheaper
AB Phylline CapsuleSun Pharmaceutical Industries Ltdcapsule · 15 Capsules₹29284% more
AB-Flo SRLUPIN LABTABLET · 10`S₹29284% more
Ab Flo CapsuleLUPIN LABcapsule · 15`S₹30894% more
See all substitutes and alternatives

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Macphylline Syrup FAQs

What is Macphylline Syrup used for?
Macphylline Syrup is commonly used for Macphylline Capsule is used in the treatment of chronic obstructive pulmonary disease. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Macphylline Syrup?
Macphylline Syrup contains Acebrophylline (100mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Macphylline Syrup?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Macphylline Syrup work?
Macphylline Capsule is a mucolytic and bronchodilator.
Is Macphylline Syrup a prescription medicine?
Yes. Macphylline Syrup is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Macphylline Syrup?
The side effects reported most often with Macphylline are Nausea, Vomiting, Stomach upset, Drowsiness, Tremor. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Macphylline Syrup be taken during pregnancy?
Information regarding the use of Macphylline Capsule during pregnancy is not available. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Macphylline.
Can I drink alcohol while taking Macphylline Syrup?
Macphylline Capsule may cause excessive drowsiness with alcohol.
What if I miss a dose of Macphylline Syrup?
Take it as soon as you remember.
Is Macphylline Syrup habit forming?
No. Macphylline Syrup is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Macphylline Syrup?
Brace-100 has the same active ingredient and strength and is listed from ₹107 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Macphylline Syrup cost on PingMeDoc Pharmacy?
Macphylline Syrup starts at ₹159 on PingMeDoc Pharmacy. Available in syrup syrup 100ML. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Macphylline Syrup?
Macphylline Syrup is manufactured by MACLEODS PHARMACEUTICALS LTD. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Macphylline Syrup delivered?
Macphylline Syrup is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Macphylline Syrup, Quick facts

Salt
Acebrophylline (100mg)
Form
syrup
Best price
₹159 (₹1.59 per ml)
Prescription
Required (Rx)
Schedule
Schedule H
Brand
Macleods Pharmaceuticals Pvt Ltd
Manufacturer
MACLEODS PHARMACEUTICALS LTD
Therapeutic class
Cough and cold preparation
Drug class
Expectorant / mucolytic / bronchodilator
Habit forming
No
Variants
syrup syrup 100ML
Delivery
Standard across India

References

The information on Macphylline Syrup is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Macphylline Syrup.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.