
Aceclo 100MG
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Prescription required
Ampicillin 250 mg (as ampicillin sodium) injection, vial
Megapen 250 mg Injection Vial is used for treatment of susceptible bacterial infections such as respiratory tract infections, urinary tract infections, gastrointestinal infections (including enteric fever/typhoid as per susceptibility), skin and soft tissue infections, and septicemia; also used for perioperative prophylaxis where appropriate.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026
Megapen 250 mg Injection Vial contains Ampicillin 250 mg (as ampicillin sodium) injection, vial. It belongs to the Penicillin (beta-lactam) antibiotic class of medicines.
Ampicillin is a beta-lactam penicillin antibiotic. It inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, leading to cell lysis and death in susceptible bacteria.
Injection to be administered by a healthcare professional only (IV/IM as prescribed). Dose and duration depend on infection type, severity, kidney function and culture sensitivity. Reconstitute/dilute as per label instructions and use immediately after preparation; complete the full prescribed course.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take the missed dose of Megapen as soon as you remember. If it is almost time for the next dose, skip the missed one and carry on with the usual schedule. Do not take two doses together to make up for a missed dose.
Taking more Megapen than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.
Most side effects of Megapen are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Generally safe (use on doctor’s advice) |
|---|---|
| Alcohol | Use with caution |
| Habit forming | No |
Prescription-only antibiotic. Do not use in patients with known hypersensitivity to penicillins; use caution in patients with history of allergy/asthma (risk of anaphylaxis). Use with caution in infectious mononucleosis (high risk of rash). Monitor for severe diarrhea/colitis (C. difficile) and discontinue if suspected. Dose adjustment may be needed in renal impairment. Prolonged use may cause superinfection; monitor blood counts with long courses.
Allopurinol (increased risk of rash), probenecid (increases ampicillin levels), methotrexate (reduced clearance/toxicity risk), oral anticoagulants such as warfarin (may increase INR), oral contraceptives (possible reduced efficacy—advise backup), bacteriostatic antibiotics like tetracyclines/chloramphenicol (may reduce efficacy)
Store as per label, typically below 25°C, protected from light and moisture. Keep vial in outer carton. After reconstitution, use promptly; discard unused portion as per local guidelines.

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The information on Megapen 250 mg Injection Vial is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.