Miacalcic Nasal Spray

Composition of Miacalcic Nasal Spray

Miacalcic Nasal Spray contains Calcitonin (Salmon) 200 IU per metered dose (nasal spray). It belongs to the Calcitonin (salmon) hormone; antiresorptive agent class of medicines.

Uses of Miacalcic Nasal Spray

Treatment of postmenopausal osteoporosis in women (usually >5 years after menopause) to reduce bone loss; may be used in Paget’s disease of bone when other treatments are not suitable; may be used for hypercalcaemia of malignancy (typically injectable form—use as per physician advice).

Key benefits

• Helps reduce bone loss in postmenopausal osteoporosis
• May reduce risk of vertebral fractures in some patients
• Provides non-oral option for patients unable to take tablets
• Can help reduce bone pain in Paget’s disease (as prescribed)

How Miacalcic Nasal Spray works

Salmon calcitonin is a hormone that lowers blood calcium and inhibits osteoclast-mediated bone resorption. It helps slow bone breakdown and can modestly improve bone mineral density and reduce vertebral fracture risk in some patients.

How to take Miacalcic Nasal Spray

Use only in the nose as prescribed. Prime the pump before first use as per pack insert. Usually 1 spray (200 IU) once daily, alternating nostrils each day; use at the same time daily. Avoid blowing nose immediately after dosing; if you miss a dose, take the next dose as scheduled.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take the missed dose of Miacalcic Nasal as soon as you remember. If it is almost time for the next dose, skip the missed one and carry on with the usual schedule. Do not take two doses together to make up for a missed dose.

If you take too much

Taking more Miacalcic Nasal than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.

Side effects of Miacalcic Nasal Spray

Most side effects of Miacalcic Nasal are mild and settle as the body adjusts. Reported side effects include:

• Nasal irritation
• runny nose (rhinitis)
• nosebleed (epistaxis)
• sneezing
• headache
• dizziness
• nausea
• flushing
• altered taste
• sore throat

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Miacalcic Nasal Spray

Warnings and precautions

Prescription medicine. Do not use if allergic to calcitonin/salmon proteins. Nasal adverse effects are common—seek medical advice for persistent ulceration, severe irritation or recurrent nosebleeds. Rare severe allergic reactions (including anaphylaxis) can occur. Long-term use has been associated with a small increased risk of malignancy in some studies; use the lowest effective duration and follow doctor’s advice. Ensure adequate calcium and vitamin D intake if prescribed. Caution in patients with hypocalcaemia—correct calcium levels before starting.

Interactions with other medicines

No major clinically significant interactions are common; concomitant lithium may reduce lithium levels (monitor). Use caution with other drugs affecting calcium/bone metabolism (e.g., bisphosphonates, denosumab) as per specialist advice.

How to store Miacalcic Nasal Spray

Store refrigerated at 2–8°C (do not freeze). Protect from light. After first use, store as directed on pack (often at room temperature below 25°C for a limited period) and keep the bottle upright; discard after the in-use period mentioned in the leaflet.

Manufacturer and class

Manufacturer:

NOVARTIS INDIA LIMITED

Therapeutic class:

Anti-osteoporotic (Bone metabolism regulator)

Drug class:

Calcitonin (salmon) hormone; antiresorptive agent