Moxclav Ds 457 Oral Suspension

Composition of Moxclav Ds 457 Oral Suspension

Moxclav Ds 457 Oral Suspension contains Amoxicillin 400 mg + Clavulanic acid 57 mg per 5 mL oral suspension (as amoxicillin trihydrate and potassium clavulanate). It belongs to the Penicillin antibiotic + Beta-lactamase inhibitor class of medicines.

Uses of Moxclav Ds 457 Oral Suspension

• Treatment of susceptible bacterial infections such as ear infections (otitis media)
• sinusitis
• throat/tonsil infections
• lower respiratory tract infections (bronchitis/pneumonia)
• urinary tract infections
• skin and soft tissue infections
• and dental infections.

Key benefits

• Broad-spectrum coverage including beta-lactamase producers
• Effective for ENT and respiratory infections
• Useful in skin/soft tissue and dental infections
• Helps treat susceptible urinary tract infections

How Moxclav Ds 457 Oral Suspension works

Amoxicillin is a penicillin antibiotic that kills bacteria by inhibiting bacterial cell wall synthesis. Clavulanic acid is a beta-lactamase inhibitor that protects amoxicillin from breakdown by beta-lactamase–producing bacteria, thereby extending its spectrum.

How to take Moxclav Ds 457 Oral Suspension

Oral suspension: Shake well before use. Measure dose with a measuring cup/oral syringe. Usually given with food at the start of a meal to reduce stomach upset. Follow the doctor’s prescribed dose and duration; complete the full course. Reconstitute with boiled and cooled water up to the mark as per label instructions.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause vomiting, severe loose motions and, rarely, fits. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Moxclav Ds 457 Oral Suspension

Most side effects of Moxclav Ds are mild and settle as the body adjusts. Reported side effects include:

• Diarrhoea
• nausea
• vomiting
• abdominal pain
• indigestion
• rash
• urticaria
• oral/vaginal thrush
• headache

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Moxclav Ds 457 Oral Suspension

Warnings and precautions

Prescription-only (Schedule H). Do not use in patients with allergy to penicillins/cephalosporins or history of severe hypersensitivity. Use with caution in liver disease; may cause hepatitis/cholestatic jaundice—stop and seek care if yellowing of skin/eyes, dark urine, severe fatigue. Adjust dose in renal impairment. Prolonged use may cause superinfection. Seek immediate help for severe diarrhoea (possible C. difficile), severe skin rash, breathing difficulty, or swelling of face/lips.

Do not take Moxclav Ds if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for anyone with a known penicillin allergy.

Interactions with other medicines

Warfarin/other anticoagulants (may increase INR), probenecid (increases amoxicillin levels), allopurinol (increased rash risk), methotrexate (reduced clearance/toxicity risk), mycophenolate mofetil (reduced active metabolite exposure), oral typhoid vaccine (reduced efficacy)

How to store Moxclav Ds 457 Oral Suspension

Store dry powder at room temperature away from moisture and light. After reconstitution, store in a refrigerator (2–8°C) and do not freeze; use within the period mentioned on the label (commonly 7 days) and discard any leftover.

Expert advice for Moxclav Ds 457 Oral Suspension

Space the doses evenly through the day so the level stays steady. Take a probiotic a few hours apart if loose motions trouble you, and drink plenty of fluids. Never use a leftover antibiotic, or someone else's, for a new illness.

Manufacturer and class

Manufacturer:

Sun Pharmaceutical Industries Ltd

Therapeutic class:

Antibiotic

Drug class:

Penicillin antibiotic + Beta-lactamase inhibitor