
360 Block Gel
Common Products - Gel - 50 G
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Diacerein (50mg) + Glucosamine Sulfate Potassium Chloride (750mg) + Methyl Sulfonyl Methane (250mg)
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Orthocure Tablet is used for osteoarthritis.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Orthocure Tablet contains Diacerein (50mg) + Glucosamine Sulfate Potassium Chloride (750mg) + Methyl Sulfonyl Methane (250mg). It belongs to the Non-steroidal anti-inflammatory drug and Vitamin and mineral supplement class of medicines.
Osteoarthritis
Orthocure Tablet is a combination of three medicines: Diacerein, Glucosamine Sulfate Potassium Chloride and Methyl Sulfonyl Methane, which treats osteoarthritis. Diacerein and Glucosamine Sulfate Potassium Chloride are proteoglycan synthesis stimulators while Methyl Sulfonyl Methane (MSM) is a nutritional supplement. Together, they help in the building of cartilage (the soft tissue around the joints) leading to joint repair. MSM additionally lowers inflammation (swelling) of the joints.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Orthocure Tablet should be taken with or after food.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you miss a dose of Orthocure Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
An overdose of this medicine can cause stomach bleeding, kidney failure, drowsiness and fits. It can cause vomiting and stomach pain, and with iron can be dangerous, especially in children. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Orthocure are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Consult doctor |
|---|---|
| Breastfeeding | Breast feeding CONSULT YOUR DOCTOR |
| Alcohol | Use with caution |
| Driving | Driving CONSULT YOUR DOCTOR |
| Kidney | Kidney CAUTION |
| Liver | Liver UNSAFE |
| Habit forming | No |
Take it with or just after food, and for the shortest time that works. Stop and seek urgent care for black or tarry stools, vomiting blood, or severe stomach pain — this group can cause bleeding from the stomach. Long or high-dose use raises the risk of heart attack, stroke and kidney injury, particularly in older people and those already at risk. Avoid if you are dehydrated or have an illness with vomiting or loose motions — the kidneys are vulnerable then. Must be avoided in the last three months of pregnancy. A supplement is not a substitute for a balanced diet or for treating the cause of a symptom. Iron makes stools black and can cause constipation — this is expected, but tell your doctor if it troubles you. Keep iron-containing products well out of reach of children; an overdose in a small child is a medical emergency. Check the labels of everything you take so you do not double up on the same nutrient.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active stomach ulcer, severe kidney or heart failure, or asthma triggered by aspirin or anti-inflammatory painkillers. Not in the third trimester of pregnancy.
Combining with a blood thinner or aspirin sharply raises the bleeding risk. Reduces the effect of blood pressure medicines and water tablets, and together with them can harm the kidneys. Never take two anti-inflammatory painkillers at the same time. Iron, calcium, zinc and magnesium reduce the absorption of thyroid tablets and several antibiotics — separate them by a few hours. Tea and coffee taken with iron reduce how much is absorbed; vitamin C increases it.
Store at room temperature (below 25°C), protected from light and moisture. Keep out of reach of children.
Orthocure Tablet helps in relieving symptoms of osteoarthritis. It may take several weeks to see treatment benefits. Keep taking the medicine as prescribed by your doctor. Any of the side effects other than those mentioned above if occur, do consult the treating physician. Let your doctor know if your symptoms do not improve even after two to three months of taking the medication.

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The information on Orthocure Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.