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Prescription requiredOzone Pharmaceuticals LtdGASTRO INTESTINAL

Osil Cream 50 g

Allantoin (0.5% w/w) + Calcium Dobesilate (0.5% w/w) + Hydrocortisone (0.25% w/w) + Lidocaine/Lignocaine (3% w/w)

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Same composition, in stock now. Check with your doctor or pharmacist before you switch.

  • Osil Cream₹143View

Osil Cream 50 g is used for piles.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Allantoin (0.5% w/w) + Calcium Dobesilate (0.5% w/w) + Hydrocortisone (0.25% w/w) + Lidocaine/Lignocaine (3% w/w)
Available variants: cream 50 gm 50GM
Best price: ₹156 (₹3.12 per g)
MRP: ₹164
Prescription: Required
Manufacturer: OZONE PHARMACEUTICALS LTD

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Osil Cream 50 g

Osil Cream 50 g contains Allantoin (0.5% w/w) + Calcium Dobesilate (0.5% w/w) + Hydrocortisone (0.25% w/w) + Lidocaine/Lignocaine (3% w/w). It belongs to the Topical corticosteroid class of medicines.

Uses of Osil Cream 50 g

Piles

Key benefits

  • In Piles Osil Cream helps reduce pain associated with piles (hemorrhoids) by producing a feeling of numbness at the site of application. It gives relief from swelling
  • itching and irritation caused due to piles. It also reduces pain while passing of stool. Apply Osil Cream 2-3 times a day after cleaning and drying the affected area properly. Consult your doctor if you do not see any improvement even after a week. Make sure to avoid spicy
  • oil-rich food and drink plenty of water and a fiber rich diet for a speedy recovery as well as to prevent piles in future.

How Osil Cream 50 g works

Osil Cream is a combination of four medicines: Allantoin , Calcium Dobesilate , Hydrocortisone , and Lidocaine/Lignocaine. Allantoin is a skin protectant that works like a moisturizer to soften skin. Calcium Dobesilate is a vasoprotective medicine which works on the walls of the small blood vessels and reduces their leakage and fragility. It also improves blood flow by decreasing viscosity/thickness of blood, thereby relieving inflammation (redness and swelling) in piles/haemorrhoids and promoting healing. Hydrocortisone is a steroid which reduces redness, itching, and swelling due to piles/haemorrhoids. Lidocaine/Lignocaine is a local anesthetic which works by blocking pain signals from the nerves to brain thereby decreasing the sensation of pain.

How to take Osil Cream 50 g

This medicine is for external use only. Use it in the dose and duration as advised by your doctor.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Osil Cream, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine is not a realistic risk from a moisturiser used on the skin. It may cause bloating and loose motions. It can cause weight gain, high blood sugar, bone thinning and suppression of the body's own steroid production when it is taken over a prolonged period. It is unlikely from external use. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Osil Cream 50 g

Most side effects of Osil are mild and settle as the body adjusts. Reported side effects include:

  • Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Osil Cream 50 g

PregnancyPregnancy CONSULT YOUR DOCTOR
BreastfeedingBreast feeding CONSULT YOUR DOCTOR
AlcoholAlcohol
DrivingDriving
KidneyKidney SAFE IF PRESCRIBED
LiverLiver SAFE IF PRESCRIBED
Habit formingNo

Warnings and precautions

Avoid prolonged use on large areas of the body, do not apply to broken skin, consult a doctor if symptoms persist.

Do not take Osil if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Probiotics are used with caution in people whose immune system is significantly suppressed. Not for people with an untreated systemic infection, except where the steroid is part of the treatment. Not for use on large burns or deep wounds without medical advice.

Interactions with other medicines

May interact with other topical medications; consult a healthcare provider for specific interactions.

How to store Osil Cream 50 g

Store at room temperature, away from direct sunlight and moisture.

Expert advice for Osil Cream 50 g

Osil Cream is for administration into the back passage (rectum). It must not be taken by mouth. Do not use it more often or for longer than advised by your doctor, as that can increase the chances of side effects. Use the applicator provided to insert a measured dose of cream into your back passage. Avoid getting it in the eyes, mouth or nose. Rinse with cold water if you accidentally get it in these areas. Inform your doctor if you get any signs of infection during treatment with this medicine.

Manufacturer and class

Manufacturer:
OZONE PHARMACEUTICALS LTD
Therapeutic class:
GASTRO INTESTINAL
Drug class:
Topical corticosteroid

Substitutes for Osil Cream 50 g

Medicines with the same active ingredient (Allantoin (0.5% w/w) + Calcium Dobesilate (0.5% w/w) + Hydrocortisone (0.25% w/w) + Lidocaine/Lignocaine (3% w/w)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Osil Cream 50 g
Osil CreamOZONE PHARMACEUTICALS LTDcream · 30GM₹1438% cheaper
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Osil Cream 50 g FAQs

What is Osil Cream 50 g used for?
Osil Cream 50 g is commonly used for Piles. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Osil Cream 50 g?
Osil Cream 50 g contains Allantoin (0.5% w/w) + Calcium Dobesilate (0.5% w/w) + Hydrocortisone (0.25% w/w) + Lidocaine/Lignocaine (3% w/w). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Osil Cream 50 g?
This medicine is for external use only. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Osil Cream 50 g work?
Osil Cream is a combination of four medicines: Allantoin , Calcium Dobesilate , Hydrocortisone , and Lidocaine/Lignocaine.
Is Osil Cream 50 g a prescription medicine?
Yes. Osil Cream 50 g is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Osil Cream 50 g?
The side effects reported most often with Osil are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Osil Cream 50 g be taken during pregnancy?
Pregnancy CONSULT YOUR DOCTOR Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Osil.
Can I drink alcohol while taking Osil Cream 50 g?
Alcohol
What if I miss a dose of Osil Cream 50 g?
If you miss a dose of Osil Cream, apply it as soon as possible.
Is Osil Cream 50 g habit forming?
No. Osil Cream 50 g is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Osil Cream 50 g?
Osil Cream has the same active ingredient and strength and is listed from ₹143 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Osil Cream 50 g cost on PingMeDoc Pharmacy?
Osil Cream 50 g starts at ₹156 (MRP ₹164) on PingMeDoc Pharmacy. Available in cream 50 gm 50GM. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Osil Cream 50 g?
Osil Cream 50 g is manufactured by OZONE PHARMACEUTICALS LTD. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Osil Cream 50 g delivered?
Osil Cream 50 g is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Osil Cream 50 g, Quick facts

Salt
Allantoin (0.5% w/w) + Calcium Dobesilate (0.5% w/w) + Hydrocortisone (0.25% w/w) + Lidocaine/Lignocaine (3% w/w)
Form
cream
Best price
₹156 (₹3.12 per g)
MRP
₹164
Prescription
Required (Rx)
Schedule
Schedule H
Brand
OZONE PHARMACEUTICALS LTD
Manufacturer
OZONE PHARMACEUTICALS LTD
Therapeutic class
GASTRO INTESTINAL
Drug class
Topical corticosteroid
Habit forming
No
Variants
cream 50 gm 50GM
Delivery
Standard across India

References

The information on Osil Cream 50 g is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. Indian Pharmacopoeia, manufacturer labeling, established medical literature
  2. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  3. National List of Essential Medicines (NLEM) 2022, Government of India.
  4. Manufacturer's package insert / prescribing information for Osil Cream 50 g.
  5. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.