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Icarus Healthcare - Tablet - 200mg + 200mg - 10 S
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Prescription required
Pregabalin (75mg) + Alpha Lipoic Acid (100mg) + Vitamin B12 (750mcg) + Folic Acid (1.5mg) + Vitamin B6 (3mg)
Available at our pharmacy counter
This medicine is dispensed in person against a valid prescription and is not sold online. Ask our pharmacist about availability, or speak to a registered doctor.
In-store reference price ₹147
Pregalus M Tablet is used for pregalus M Capsule is used in the treatment of neuropathic pain.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Pregalus M Tablet contains Pregabalin (75mg) + Alpha Lipoic Acid (100mg) + Vitamin B12 (750mcg) + Folic Acid (1.5mg) + Vitamin B6 (3mg). It belongs to the Gabapentinoid, Antioxidant / trace element supplement and B-complex vitamin class of medicines.
Pregalus M Capsule is used in the treatment of neuropathic pain.
Pregalus M Capsule is a combination of five medicines: Alpha Lipoic Acid, Folic Acid, Methylcobalamin/Mecobalamin, Pregabalin and Vitamin B6 (Pyridoxine). Alpha Lipoic Acid is a naturally occurring fatty acid which has a protective effect on the brain and nerve tissues. Folic Acid provides essential nutrients to the nerves. Methylcobalamin/Mecobalamin and Vitamin B6 (Pyridoxine) are forms of vitamin B which help in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Pregabalin is an alpha 2 delta ligand which decreases pain by modulating calcium channel activity of the nerve cells. Together, they relieve neuropathic pain (pain from damaged nerves).
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pregalus M Capsule is to be taken empty stomach.<br>Take it 30 minutes before food.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause deep drowsiness, confusion, unsteadiness and slowed breathing, especially with an opioid or alcohol. It can cause vomiting, stomach pain and, with some minerals, damage over the longer term. It is unlikely to cause serious harm, because the body passes surplus B vitamins out in the urine. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Pregalus M are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Pregalus M Capsule may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor. |
|---|---|
| Breastfeeding | Pregalus M Capsule is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby. |
| Alcohol | Pregalus M Capsule may cause excessive drowsiness and calmness with alcohol. |
| Driving | Do not drive or operate machinery while taking this medicine. |
| Kidney | Pregalus M Capsule is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Pregalus M Capsule may not be needed in these patients. Please consult your doctor. |
| Liver | Pregalus M Capsule is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Pregalus M Capsule may not be needed in these patients. Please consult your doctor. |
| Habit forming | Yes |
This medicine causes drowsiness and unsteadiness, particularly when you start it or the dose goes up. Do not drive or operate machinery until you know how it affects you. Never stop it suddenly. Stopping abruptly can cause anxiety, sleeplessness, sweating and, in people taking it for epilepsy, fits. Your doctor will taper it. Tell your doctor about any change in mood or any thoughts of harming yourself. The dose is usually built up slowly from a low starting point — follow the schedule your doctor gave you rather than jumping to the full dose. Pregabalin comes under Schedule H1 from 16 November 2026 and will then need a prescription and a pharmacy register entry. A supplement supports a normal diet; it does not prevent or treat infection. Zinc on an empty stomach commonly causes nausea — take it with food. Very high doses of vitamin A over a long period can be harmful, particularly in pregnancy. Do not take several products containing the same nutrient at once; the totals add up. Tingling, numbness or burning in the hands and feet should be assessed by a doctor rather than self-treated — a supplement does not address the cause. Folic acid can mask a vitamin B12 deficiency while nerve damage continues, so B12 should be checked before taking folic acid long term. Bright yellow urine after a B-complex dose is expected and harmless.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack.
Opioid painkillers, alcohol, sleeping tablets and antihistamines all add to the drowsiness, and the combination with opioids can dangerously slow breathing. Antacids reduce the absorption of gabapentin — separate them by a couple of hours. Zinc and other minerals reduce the absorption of some antibiotics — separate them by a few hours. Tell your doctor if you take a blood thinner, as high-dose vitamin E can add to its effect. Long-term metformin, acid-reducing medicines and some anti-epileptics lower B12 or folate levels. Tell your doctor if you take levodopa, as vitamin B6 can reduce its effect.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Take the larger part of the dose at night if drowsiness is a problem. Rise slowly from sitting or lying, especially in the first weeks. Keep your review appointment so the dose can be adjusted to the lowest that controls your pain. Take it with food to reduce nausea. A varied diet remains the best source of these nutrients. A supplement corrects a deficiency; it is not a general energy tonic. If you are on it for nerve symptoms, keep your review appointment so the underlying cause is looked for.

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The information on Pregalus M Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.