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Dr Reddys Laboratories Ltd - Tablet - 100mg + 325mg + 65mg - 10 S
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Rupatadine (10mg) + Montelukast (10mg)
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Rupanex M Tablet is used for sneezing and runny nose due to allergies.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Rupanex M Tablet contains Rupatadine (10mg) + Montelukast (10mg). It belongs to the Antihistamine / leukotriene antagonist class of medicines.
Sneezing and runny nose due to allergies
Rupanex M Tablet is a combination of two medicines: Rupatadine and Montelukast, which treats sneezing and runny nose caused due to allergies. Rupatadine is an antiallergic which blocks the action a chemical messenger (histamine) responsible for runny nose, watery eyes and sneezing. Montelukast is a leukotriene antagonist. It works by blocking the action of another chemical messenger (leukotriene). This reduces inflammation (swelling) in the airways and nose, and improves symptoms.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rupanex M Tablet may be taken with or without food.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you miss a dose of Rupanex M Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
An overdose of this medicine can cause severe drowsiness, a fast heartbeat, confusion and, in children, agitation and fits. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Rupanex M are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Pregnancy CONSULT YOUR DOCTOR |
|---|---|
| Breastfeeding | Breast feeding CONSULT YOUR DOCTOR |
| Alcohol | Alcohol CAUTION |
| Driving | Driving UNSAFE |
| Kidney | Kidney CAUTION |
| Liver | Liver CAUTION |
| Habit forming | No |
Older antihistamines cause marked drowsiness — do not drive or operate machinery until you know how this affects you. Tell your doctor promptly about any change in mood, sleep, agitation or unusual thoughts while taking montelukast; this is uncommon but recognised. This relieves the symptoms of an allergy; it does not treat the cause, and it is not a treatment for an acute asthma attack. Seek emergency care for swelling of the lips, tongue or throat, or difficulty breathing.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. The sedating antihistamines are not suitable for very young children, or for people with glaucoma or an enlarged prostate, without medical advice.
Alcohol, sleeping tablets and other sedating medicines add to the drowsiness. Tell your doctor about all cold and cough preparations — many already contain an antihistamine.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
You have been prescribed Rupanex M Tablet to help relieve symptoms of allergy such as runny nose, sneezing, watery eyes, and cough. Be cautious while driving or doing anything that requires concentration as Rupanex M Tablet can cause dizziness and sleepiness. Do not drink alcohol while taking Rupanex M Tablet as it may cause increased sleepiness. Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help. Stop taking Rupanex M Tablet at least three days before taking an allergy test as it can affect the test results.

Dr Reddys Laboratories Ltd - Tablet - 100mg + 325mg + 65mg - 10 S
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The information on Rupanex M Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.