Semi Amaryl M Tablet

Composition of Semi Amaryl M Tablet

Semi Amaryl M Tablet contains Glimepiride (0.5mg) + Metformin (500mg). It belongs to the Sulfonylurea and Biguanide class of medicines.

Uses of Semi Amaryl M Tablet

Treatment of Type 2 diabetes mellitus Hormone replacement therapy

Key benefits

• In Treatment of Type 2 diabetes mellitus Semi Amaryl M Tablet PR is a combination medicine that increases the amount of insulin your body produces (in the pancreas). The insulin then works to lower your blood glucose level. It is usually taken once a day. You should keep taking it for as long as it is prescribed. Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level
• you will reduce the risk of getting any of the serious complications of diabetes
• such as kidney damage
• eye damage
• nerve problems
• and loss of limbs. Taking this medicine regularly
• along with proper diet and exercise
• will help you live a normal
• healthy life. In Hormone replacement therapy In patients already controlled on separate treatment with glimepiride and metformin
• this combination may be used as a replacement to simplify treatment while maintaining blood sugar control. It is indicated in adults 18 years and older. Show More

How Semi Amaryl M Tablet works

Semi Amaryl M Tablet PR is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea that works by increasing the amount of insulin released by the pancreas to lower the blood glucose. Metformin is a biguanide that works by lowering glucose production in the liver, delaying glucose absorption from the intestines, and increasing the body's sensitivity to insulin.

How to take Semi Amaryl M Tablet

Use it as advised by your doctor or check the label for directions before use. Semi Amaryl M Tablet PR should be taken with or after food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Semi Amaryl M Tablet PR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Semi Amaryl M Tablet

Most side effects of Semi Amaryl M are mild and settle as the body adjusts. Reported side effects include:

• Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Semi Amaryl M Tablet

Warnings and precautions

If you feel shaky, sweaty, confused or unusually hungry, take sugar, glucose or a sweet drink at once and tell your doctor — these are signs your blood sugar has fallen too low. Do not skip meals while on this medicine — a missed meal is the commonest cause of a low-sugar episode. Carry glucose, sugar or sweets with you, and tell the people you live and work with what a low-sugar episode looks like. Older people and people with kidney trouble are more likely to have low sugar, and may need a smaller dose. Stomach upset is common in the first two weeks and usually settles; taking it with food helps. Tell your doctor before any surgery or a scan that uses contrast dye — this medicine is usually stopped for a short time around them. Stop and seek urgent care if you develop deep rapid breathing, severe weakness, muscle pain or vomiting with cold clammy skin. This is rare but serious. Long-term use can lower vitamin B12, so your doctor may check it from time to time.

Do not take Semi Amaryl M if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.

Interactions with other medicines

Many medicines change how strongly this works — tell your doctor about aspirin, blood thinners, antifungals, sulfa antibiotics and beta blockers in particular. Beta blockers can mask the warning signs of low blood sugar. Tell your doctor about water tablets, steroids, and any contrast dye scan. Alcohol increases the risk of the rare acid build-up and should be limited.

How to store Semi Amaryl M Tablet

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Semi Amaryl M Tablet

You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Semi Amaryl M Tablet PR. Take it with food to lower your chance of having an upset stomach. Monitor your blood sugar level regularly while you are taking this medicine. It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Semi Amaryl M Tablet PR may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood. Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Manufacturer and class

Manufacturer:

SANOFI INDIA LTD

Therapeutic class:

ANTI DIABETIC

Drug class:

Sulfonylurea and Biguanide