Glucoryl M 0.5

Composition of Glucoryl M 0.5

Glucoryl M 0.5 contains Metformin (500mg) + Glimepiride (0.5mg). It belongs to the Biguanide and Sulfonylurea class of medicines.

Uses of Glucoryl M 0.5

Glucoryl-M 0.5 mg Tablet is used in the treatment of type 2 diabetes.

Key benefits

• First-choice medicine for type 2 diabetes
• Does not usually cause weight gain
• Low risk of hypoglycaemia when used alone
• Lowers blood sugar quickly
• Long-established and inexpensive

How Glucoryl M 0.5 works

Glucoryl-M 0.5 mg Tablet is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.

How to take Glucoryl M 0.5

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glucoryl-M 0.5 mg Tablet is to be taken with food.<br>Glucoryl-M 0.5 mg Tablet may cause stomach upset if taken empty stomach.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. It can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Glucoryl M 0.5

Most side effects of Glucoryl M are mild and settle as the body adjusts. Reported side effects include:

• Hypoglycemia (low blood sugar level) Taste change Nausea Diarrhea Stomach pain Headache Upper respiratory tract infection

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Glucoryl M 0.5

Warnings and precautions

Stomach upset is common in the first two weeks and usually settles; taking it with food helps. Tell your doctor before any surgery or a scan that uses contrast dye — this medicine is usually stopped for a short time around them. Stop and seek urgent care if you develop deep rapid breathing, severe weakness, muscle pain or vomiting with cold clammy skin. This is rare but serious. Long-term use can lower vitamin B12, so your doctor may check it from time to time. If you feel shaky, sweaty, confused or unusually hungry, take sugar, glucose or a sweet drink at once and tell your doctor — these are signs your blood sugar has fallen too low. Do not skip meals while on this medicine — a missed meal is the commonest cause of a low-sugar episode. Carry glucose, sugar or sweets with you, and tell the people you live and work with what a low-sugar episode looks like. Older people and people with kidney trouble are more likely to have low sugar, and may need a smaller dose.

Do not take Glucoryl M if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease.

Interactions with other medicines

Tell your doctor about water tablets, steroids, and any contrast dye scan. Alcohol increases the risk of the rare acid build-up and should be limited. Many medicines change how strongly this works — tell your doctor about aspirin, blood thinners, antifungals, sulfa antibiotics and beta blockers in particular. Beta blockers can mask the warning signs of low blood sugar.

How to store Glucoryl M 0.5

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Glucoryl M 0.5

<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li><div>You have been prescribed this combination medicine as it can control blood sugar better than metformin alone.</div></li> <li>You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Zoryl M 0.5 Tablet PR.</li> <li>Take it with food to lower your chance of having an upset stomach.</li> <li>Monitor your blood sugar level regularly while you are taking this medicine. </li> <li>Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.</li> <li>It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. </li> <li>Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Zoryl M 0.5 Tablet PR may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.</li> <li>Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).</li></ul></div></div></div></div></div></div>

Manufacturer and class

Manufacturer:

ALKEM LAB

Therapeutic class:

Anti-diabetic

Drug class:

Biguanide and Sulfonylurea