Sitaearth M 500 Tablet

Composition of Sitaearth M 500 Tablet

Sitaearth M 500 Tablet contains Sitagliptin 50 mg + Metformin 500 mg (as Metformin Hydrochloride). It belongs to the DPP-4 inhibitor + Biguanide class of medicines.

Uses of Sitaearth M 500 Tablet

• Type 2 diabetes mellitus: to improve blood sugar control in adults
• along with diet and exercise

Key benefits

• Lowers fasting and post-meal blood sugar
• Improves insulin sensitivity
• Helps reduce HbA1c
• Low risk of hypoglycaemia when used alone
• Weight-neutral/less weight gain compared with some therapies

How Sitaearth M 500 Tablet works

Sitagliptin is a DPP-4 inhibitor that increases incretin levels, which boosts insulin release and reduces glucagon after meals. Metformin decreases glucose production in the liver and improves insulin sensitivity, helping lower fasting and post-meal blood sugar.

How to take Sitaearth M 500 Tablet

Oral tablet. Usually taken with meals to reduce stomach upset; swallow whole with water. Dose and frequency are as prescribed by the doctor; do not crush or chew. Monitor blood glucose regularly.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine may cause low blood sugar, particularly if you also take other diabetes medicines. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Sitaearth M 500 Tablet

Most side effects of Sitaearth M are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• vomiting
• diarrhoea
• abdominal pain
• loss of appetite
• metallic taste
• headache
• dizziness
• nasopharyngitis
• upper respiratory tract infection

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Sitaearth M 500 Tablet

Warnings and precautions

Prescription medicine. Risk of lactic acidosis with metformin (higher risk in kidney impairment, dehydration, severe infection, shock, heavy alcohol use). Do not use in severe renal impairment; kidney function should be checked before and during treatment. Temporarily stop metformin before/after iodinated contrast procedures and major surgery as advised. Use with caution in liver disease, heart failure, elderly, and in conditions causing low oxygen. Seek help for symptoms of pancreatitis (severe abdominal pain), allergic reactions, or persistent severe GI symptoms. Monitor for hypoglycaemia when used with insulin or sulfonylureas.

Do not take Sitaearth M if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.

Interactions with other medicines

Alcohol (increases lactic acidosis risk), insulin and sulfonylureas (increased hypoglycaemia), iodinated contrast media (risk of kidney injury/lactic acidosis; temporary discontinuation), carbonic anhydrase inhibitors like topiramate/acetazolamide (increased metabolic acidosis risk), cationic drugs affecting renal tubular secretion (e.g., cimetidine) may increase metformin levels, ACE inhibitors/ARBs and diuretics (may affect glucose control/renal function)

How to store Sitaearth M 500 Tablet

Store below 25°C in a cool, dry place. Protect from moisture and direct light. Keep out of reach of children.

Expert advice for Sitaearth M 500 Tablet

It can be taken with or without food, at the same time each day. Keep up your diet and activity — this medicine supports them. Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them.

Manufacturer and class

Manufacturer:

D EARTH PHARMACEUTICALS

Therapeutic class:

Antidiabetic

Drug class:

DPP-4 inhibitor + Biguanide