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Prescription requiredSanofi India LtdDERMA

Sofradex F Cream

Dexamethasone (0.1% w/w) + Framycetin (1% w/w) + Clotrimazole (1% w/w)

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Sofradex F Cream is used for treatment of Skin infections.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated October 2026

From a dermatologist, online

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Key details

Salt: Dexamethasone (0.1% w/w) + Framycetin (1% w/w) + Clotrimazole (1% w/w)
Available variants: cream 0.1%w/w + 1%w/w + 1%w/w 10GM
Best price: ₹80 (₹8.02 per g)
MRP: ₹84
Prescription: Required
Manufacturer: SANOFI INDIA LTD

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Sofradex F Cream

Sofradex F Cream contains Dexamethasone (0.1% w/w) + Framycetin (1% w/w) + Clotrimazole (1% w/w). It belongs to the Systemic corticosteroid, Topical antibacterial and Antifungal class of medicines.

Uses of Sofradex F Cream

Treatment of Skin infections

Benefits of Sofradex F Cream

In Inflammation
Sofradex F powerfully suppresses inflammation anywhere in the body, bringing severe swelling, pain and tissue damage under control quickly.
In Allergic reactions
Sofradex F calms a severe allergic reaction, reducing swelling, rash and breathing difficulty.
In Autoimmune conditions
Sofradex F dampens the immune system's attack on the body's own tissues, controlling flares of conditions such as rheumatoid arthritis, lupus and inflammatory bowel disease.
In Asthma flare
Sofradex F settles the airway inflammation of a severe asthma attack over a few days, restoring normal breathing and preventing the attack from worsening.
In Skin infection
Sofradex F kills the bacteria infecting the skin, so the redness, swelling, pain and discharge settle and the skin heals.
In Infected wounds
Sofradex F clears infection from a cut, graze or wound so it can heal cleanly, and helps prevent infection in a wound at risk.
In Impetigo
Sofradex F clears the crusted, weeping sores of impetigo and stops them spreading to other areas or to other people.
In Boils
Sofradex F treats the bacterial infection in a boil or folliculitis, reducing the pain and swelling and helping it heal.
In Fungal skin infection
Sofradex F kills the fungus on the skin or stops it growing, clearing the rash and the itch. Continuing for the full period, even after the skin looks clear, stops it coming back.
In Ringworm
Sofradex F clears the ring-shaped, itchy rash of ringworm and stops it spreading to other parts of the body or to other people.
In Athlete's foot
Sofradex F clears the itchy, peeling, cracked skin between the toes and on the soles, and helps stop the infection returning.
In Dandruff
Sofradex F controls the yeast that drives flaking and itching of the scalp, so dandruff clears and the scalp settles.
In Nail fungal infection
Sofradex F, applied to the nail, slowly clears a mild fungal nail infection as the healthy nail grows out.

How Sofradex F Cream works

Sofradex-F Cream is a combination of three medicines: Dexamethasone, Framycetin and Clotrimazole. Dexamethasone is a steroid which blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen and itchy. Clotrimazole is an antifungal medication. It kills and stops the growth of the fungi by destroying its cell membrane. Framycetin is an antibiotic. It stops bacterial growth on the skin, by preventing synthesis of essential proteins required by bacteria to carry out vital functions. Together, they treat your skin infection effectively.

How to take Sofradex F Cream

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Sofradex-F Cream, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause weight gain, high blood sugar, bone thinning and suppression of the body's own steroid production when it is taken over a prolonged period. It is unlikely from skin use. It is unlikely from skin use; swallowing the preparation may cause stomach upset. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Sofradex F Cream

Most side effects of Sofradex F are mild and settle as the body gets used to the medicine. The ones reported most often are:

  • Increased appetite and weight gain
  • Raised blood sugar
  • Difficulty sleeping
  • Mood change
  • Indigestion
  • Fluid retention
  • Burning or stinging
  • Itching
  • Redness
  • Dryness
  • Peeling

Stop the medicine and get help at once for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Sofradex F Cream

AlcoholCAUTION
Alcohol may worsen the side effects of this medicine. Limit it.
PregnancyCONSULT YOUR DOCTOR
Consult your doctor before using this in pregnancy.
Breast feedingCONSULT YOUR DOCTOR
Consult your doctor before using this while breastfeeding.
DrivingSAFE
Not expected to affect your ability to drive.
KidneyCAUTION
Use with caution if you have kidney disease. Your doctor may adjust the dose or monitor your kidney function.
LiverCAUTION
Use with caution if you have liver disease. Your doctor may adjust the dose or monitor your liver function.

Warnings and precautions

Never stop a course of more than a few days suddenly. Your body stops making its own steroid while you take these, and abrupt withdrawal can cause a dangerous collapse. Your doctor will taper the dose. Tell any doctor treating you that you take steroids, and say so urgently if you develop a serious infection, injury or need surgery — you may need a higher dose to cope. Steroids raise blood sugar. If you have diabetes, monitor it more closely during a course. Long-term use thins bones, raises the risk of infection, cataract and glaucoma. Your doctor will monitor and may add bone protection. Chickenpox and measles can be severe in people on steroids — seek advice promptly after any contact. Use it for the short course prescribed, usually about a week. Prolonged use of a topical antibiotic breeds resistant bacteria. See a doctor if the area becomes more red, swollen, painful or spreads, or if you develop a fever — a spreading skin infection needs tablets. Clean the area gently before each application. Do not use it on large raw areas or burns unless your doctor has said to. Keep applying for the full period your doctor stated, usually two to four weeks, and for a week or two after the rash has cleared. Stopping when it looks better is why ringworm keeps coming back. Apply a little beyond the visible edge of the patch — the fungus extends further than the redness. Do not use a combination cream containing a steroid on a fungal infection unless a doctor has specifically prescribed it. The steroid calms the redness while the fungus spreads underneath. See a doctor if the rash covers a large area, involves the scalp or nails, or has not improved in two weeks — these usually need tablets as well.

Do not take Sofradex F if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an untreated systemic infection, except where the steroid is part of the treatment. Not for use in or around the eyes. For external use only. Not for use in the eyes.

Interactions with other medicines

Anti-inflammatory painkillers together with steroids markedly raise the risk of stomach bleeding. Live vaccines are generally avoided during significant steroid treatment. No significant interactions are expected from preparations used on the skin.

How to store Sofradex F Cream

Store below 30°C, away from direct sunlight. Close the cap tightly after each use. Keep out of the reach of children.

Quick tips for Sofradex F Cream

  • Sofradex-F Cream must be applied as a thin layer on the affected area as prescribed by your doctor.
  • Do not use this medicine more often or for longer than advised by your doctor.
  • Before each application, wash the affected area with soap and water and dry well.
  • Avoid getting it in the eyes, mouth or nose.
  • Rinse with cold water if you accidentally get it in these areas.
  • Do not cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
  • Inform your doctor if the treated skin area does not improve after 2-4 weeks of treatment.

Manufacturer and class

Manufacturer:
SANOFI INDIA LTD
Therapeutic class:
DERMA
Drug class:
Systemic corticosteroid, Topical antibacterial and Antifungal

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Sofradex F Cream FAQs

What is Sofradex F Cream used for?
Sofradex F Cream is commonly used for Treatment of Skin infections. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What are the benefits of Sofradex F Cream?
Inflammation: Sofradex F powerfully suppresses inflammation anywhere in the body, bringing severe swelling, pain and tissue damage under control quickly. It is also used for allergic reactions, autoimmune conditions, asthma flare.
What is the salt in Sofradex F Cream?
Sofradex F Cream contains Dexamethasone (0.1% w/w) + Framycetin (1% w/w) + Clotrimazole (1% w/w). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Sofradex F Cream?
This medicine is for external use only. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Sofradex F Cream work?
Sofradex-F Cream is a combination of three medicines: Dexamethasone, Framycetin and Clotrimazole.
Is Sofradex F Cream a prescription medicine?
Yes. Sofradex F Cream is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Sofradex F Cream?
The side effects reported most often with Sofradex F are Increased appetite and weight gain, Raised blood sugar, Difficulty sleeping, Mood change, Indigestion. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Sofradex F Cream be taken during pregnancy?
Consult your doctor before taking Sofradex F Cream in pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Sofradex F.
Can I drink alcohol while taking Sofradex F Cream?
Limit alcohol while taking Sofradex F Cream; it can worsen the side effects.
What if I miss a dose of Sofradex F Cream?
If you miss a dose of Sofradex-F Cream, apply it as soon as possible.
Is Sofradex F Cream habit forming?
No. Sofradex F Cream is not known to be habit forming when taken as prescribed.
How much does Sofradex F Cream cost on PingMeDoc Pharmacy?
Sofradex F Cream starts at ₹80 (MRP ₹84) on PingMeDoc Pharmacy. Available in cream 0.1%w/w + 1%w/w + 1%w/w 10GM. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Sofradex F Cream?
Sofradex F Cream is manufactured by SANOFI INDIA LTD. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Sofradex F Cream delivered?
Sofradex F Cream is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Sofradex F Cream, Quick facts

Salt
Dexamethasone (0.1% w/w) + Framycetin (1% w/w) + Clotrimazole (1% w/w)
Form
cream
Best price
₹80 (₹8.02 per g)
MRP
₹84
Prescription
Required (Rx)
Schedule
Schedule H
Brand
SANOFI INDIA LTD
Manufacturer
SANOFI INDIA LTD
Therapeutic class
DERMA
Drug class
Systemic corticosteroid, Topical antibacterial and Antifungal
Habit forming
No
Variants
cream 0.1%w/w + 1%w/w + 1%w/w 10GM
Delivery
Standard across India

References

Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered pharmacist. It does not replace your own doctor's advice.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Sofradex F Cream.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.