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Sun Pharma - Capsule - 15 S
Prescription required
Domperidone (30mg) + Esomeprazole (40mg)
Sompraz D 20 Capsule is used for treatment of Gastroesophageal reflux disease (Acid reflux).
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Medicines with the same active ingredient and strength as Sompraz D 20 Capsule.
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Sompraz D 20 Capsule
capsule - 15 Capsules
₹188
₹12.50 per capsule
Blue Cross Laboratories Pvt Ltd · capsule - 15 S · Rx
₹75
₹5.00 per capsule
AGARAM MEDICAL SERVICES · capsule - 10 S · Rx
₹76
₹7.56 per capsule
MEXICAN WAVE PHARMA · capsule - 10 S · Rx
₹76
₹7.59 per capsule
A substitute contains the same active ingredient (salt), in the same strength, as Sompraz D 20 Capsule. The medicine inside is the same — the brand name, manufacturer and price are what differ.
All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.
Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.
Sompraz D 20 Capsule contains Domperidone (30mg) + Esomeprazole (40mg). It belongs to the Anti-emetic / prokinetic and Proton pump inhibitor class of medicines.
Treatment of Gastroesophageal reflux disease (Acid reflux)
Sompraz D 40 Capsule SR is a combination of two medicines: Domperidone and Esomeprazole. Domperidone is a prokinetic that works on the upper digestive tract to increase the movement of the stomach and intestines, allowing the food to move more easily through the stomach. Esomeprazole is a proton pump inhibitor (PPI) that works by reducing the amount of acid in the stomach, which helps in the relief of acid-related indigestion and heartburn.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sompraz D 40 Capsule SR is to be taken on an empty stomach.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you miss a dose of Sompraz D 40 Capsule SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
An overdose of this medicine can cause drowsiness, disorientation and abnormal muscle movements. It may cause confusion, blurred vision, sweating and a fast heartbeat. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Sompraz D are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Pregnancy CONSULT YOUR DOCTOR |
|---|---|
| Breastfeeding | Breast feeding UNSAFE |
| Alcohol | Alcohol CONSULT YOUR DOCTOR |
| Driving | Driving UNSAFE |
| Kidney | Kidney CAUTION |
| Liver | Liver UNSAFE |
| Habit forming | No |
Use it for the shortest period that works. These medicines are not intended for long-term daily use. Report any unusual muscle stiffness, tremor, restlessness or uncontrolled movements of the face or limbs at once — stop and contact your doctor. Tell your doctor if you have a heart rhythm problem; some of this group affect the heart's electrical timing. Persistent vomiting needs a diagnosis. Do not keep suppressing it without seeing a doctor, especially with abdominal pain, fever or blood. Take it on an empty stomach, about half an hour to an hour before your first meal — this is when the acid pumps are most active and the medicine works best. Long-term use has been linked to low magnesium and low vitamin B12, and to a higher risk of bone fracture. Review the need with your doctor rather than continuing indefinitely. Tell your doctor if acidity comes with difficulty swallowing, vomiting, weight loss, or black stools — these need investigation, not a longer course. Do not stop a long course abruptly; acid can rebound. Your doctor will taper it.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with bleeding, blockage or perforation of the gut, or with certain heart rhythm disorders.
Antifungals, some antibiotics and heart-rhythm medicines increase the risk of rhythm problems when combined. Adds to the drowsiness of alcohol and sedatives. Reduces the absorption of some antifungals, iron and certain HIV medicines. Tell your doctor if you take clopidogrel, methotrexate or a blood thinner.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Take Sompraz D 40 Capsule SR on an empty stomach 30 minutes to 1 hour before the meal. It is a well-tolerated medicine and provides relief for a long time. Inform your doctor if you get watery diarrhea, fever, or stomach pain that does not go away. Long-term use can cause weak bones and a deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
Medicines with the same active ingredient (Domperidone (30mg) + Esomeprazole (40mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Sompraz D 20 Capsule |
|---|---|---|---|
| Blupraz-D CapsuleBlue Cross Laboratories Pvt Ltd | capsule · 15`S | ₹75 | 60% cheaper |
| Stopflux-D CapsuleAGARAM MEDICAL SERVICES | capsule · 10`S | ₹76 | 60% cheaper |
| Esowave D CapsuleMEXICAN WAVE PHARMA | capsule · 10`S | ₹76 | 59% cheaper |
| Somerest D CapsuleSTATURE LIFE SCIENCES PRIVATE | capsule · 10`S | ₹139 | 26% cheaper |
| Zosa Dsr CapsuleZuventus Healthcare Ltd | capsule · 15`S | ₹218 | 16% more |
| Esomac D 40 mg CapsuleCIPLA LIMITED | capsule · 10`S | ₹221 | 18% more |
| Espra Dsr CapsuleZYDUS HEALTHCARE PHARMA | capsule · 15`S | ₹226 | 21% more |
| Neksium D 40/30 mg CapsuleCIPLA LIMITED | capsule · 15`S | ₹253 | 35% more |
| Sompraz D 40 mgSUN PHARMA | 15`S | ₹263 | 40% more |
| Esofag D CapsuleMICRO LABS | capsule · 15`S | ₹293 | 56% more |
| Esoz D 40 mg CapsuleGLENMARK PHARMACEUTICALS | capsule · 15`S | ₹381 | 103% more |

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Prescription required
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The information on Sompraz D 20 Capsule is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.