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Prescription requiredRpg Life Sciences LimitedCARDIAC

Spiromide

Furosemide (20mg) + Spironolactone (50mg)

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Same composition, in stock now. Check with your doctor or pharmacist before you switch.

  • Lasilactone 50 Tablet₹65View

Spiromide is used for treatment of Resistant Hypertension (high blood pressure) Treatment of Chronic Heart Failure Treatment of Liver cirrhosis with edema.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

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Key details

Salt: Furosemide (20mg) + Spironolactone (50mg)
Available variants: NA 10`S
Best price: ₹72
MRP: ₹76
Prescription: Required
Manufacturer: RPG LIFE SCIENCES LIMITED

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Spiromide

Spiromide contains Furosemide (20mg) + Spironolactone (50mg). It belongs to the Water tablet and Potassium-sparing diuretic class of medicines.

Uses of Spiromide

Treatment of Resistant Hypertension (high blood pressure) Treatment of Chronic Heart Failure Treatment of Liver cirrhosis with edema

Key benefits

  • In Treatment of Resistant Hypertension (high blood pressure) Spiromide Tablet helps in the management of resistant hypertension (high blood pressure) that does not respond to standard diuretic therapy. It helps remove excess salt and water from the body and prevents potassium loss. This helps lower blood pressure more effectively in patients with secondary hyperaldosteronism
  • a condition where excess aldosterone causes fluid buildup and makes blood pressure harder to control. In Treatment of Chronic Heart Failure In chronic congestive cardiac failure
  • the heart struggles to pump blood effectively
  • leading to fluid buildup in the lungs and body. Spiromide Tablet helps remove this excess fluid
  • reducing swelling (edema)
  • breathlessness
  • and strain on the heart. It is especially useful in resistant edema associated with secondary hyperaldosteronism
  • where single diuretic therapy is not sufficient. In Treatment of Liver cirrhosis with edema In hepatic cirrhosis
  • impaired liver function often causes fluid accumulation in the abdomen (ascites) and swelling due to secondary hyperaldosteronism. Spiromide Tablet helps reduce this fluid buildup by removing excess salt and water while maintaining potassium balance and preventing further electrolyte disturbances. It is specifically indicated for resistant edema in patients with hepatic cirrhosis when conventional diuretic therapy alone is inadequate. Show More

How Spiromide works

Spiromide Tablet contains two medicines: furosemide and spironolactone, which act on different parts of the kidney to remove excess fluid. Furosemide is a short-acting loop diuretic that helps the kidneys eliminate sodium, chloride, and water through urine, thereby reducing fluid overload and blood pressure. Spironolactone is a long-acting aldosterone antagonist that promotes the excretion of sodium and water while conserving potassium, helping maintain electrolyte balance and preventing potassium loss during treatment.

How to take Spiromide

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Spiromide Tablet should be taken with or after food. Avoid Spiromide Tablet with dietary sodium.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Spiromide Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause severe dehydration, a sharp fall in blood pressure and dangerous salt imbalances. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Spiromide

Most side effects of Spiromide are mild and settle as the body adjusts. Reported side effects include:

  • Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Spiromide

PregnancyPregnancy CONSULT YOUR DOCTOR
BreastfeedingBreast feeding UNSAFE
AlcoholAlcohol CONSULT YOUR DOCTOR
DrivingDriving UNSAFE
KidneyKidney UNSAFE
LiverLiver CAUTION
Habit formingNo

Warnings and precautions

Take it in the morning so that passing urine does not disturb your sleep. Your doctor will check your salts and kidney function with blood tests — do not skip them. Report muscle cramps, marked weakness, confusion or an irregular heartbeat; these can be signs your potassium or sodium has fallen. In hot weather or during an illness with vomiting or loose motions, tell your doctor — you may become dehydrated quickly. This water tablet KEEPS potassium rather than losing it. Do not take potassium supplements or potassium-based salt substitutes with it unless your doctor has specifically told you to. Report muscle weakness, numbness or an irregular heartbeat — these can be signs potassium has risen too high. Breast tenderness or enlargement can occur in men; tell your doctor if it troubles you.

Do not take Spiromide if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people who are unable to pass urine, or who are severely dehydrated.

Interactions with other medicines

Anti-inflammatory painkillers blunt the effect and can strain the kidneys. Lithium and digoxin levels are affected; tell your doctor if you take either. Potassium-sparing types must not be combined with potassium supplements without supervision.

How to store Spiromide

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Spiromide

Spiromide Tablet helps remove excess water from your body. Take it in the morning with breakfast to avoid getting up at night to urinate. It may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. It may cause excessive urine production, dehydration, and low electrolyte levels. Notify your doctor if you experience dizziness, tiredness, or muscle weakness that doesn't go away. Your doctor may regularly monitor your blood pressure, kidney function, and the level of salts such as potassium and sodium in your blood while you're taking this medication.

Manufacturer and class

Manufacturer:
RPG LIFE SCIENCES LIMITED
Therapeutic class:
CARDIAC
Drug class:
Water tablet and Potassium-sparing diuretic

Substitutes for Spiromide

Medicines with the same active ingredient (Furosemide (20mg) + Spironolactone (50mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Spiromide
Lasilactone 50 TabletSANOFI INDIA LTDtablet · 10 Tablet₹6510% cheaper
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Spiromide FAQs

What is Spiromide used for?
Spiromide is commonly used for Treatment of Resistant Hypertension (high blood pressure) Treatment of Chronic Heart Failure Treatment of Liver cirrhosis with edema. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Spiromide?
Spiromide contains Furosemide (20mg) + Spironolactone (50mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Spiromide?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Spiromide work?
Spiromide Tablet contains two medicines: furosemide and spironolactone, which act on different parts of the kidney to remove excess fluid.
Is Spiromide a prescription medicine?
Yes. Spiromide is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Spiromide?
The side effects reported most often with Spiromide are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Spiromide be taken during pregnancy?
Pregnancy CONSULT YOUR DOCTOR Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Spiromide.
Can I drink alcohol while taking Spiromide?
Alcohol CONSULT YOUR DOCTOR
What if I miss a dose of Spiromide?
If you miss a dose of Spiromide Tablet, take it as soon as possible.
Is Spiromide habit forming?
No. Spiromide is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Spiromide?
Lasilactone 50 Tablet has the same active ingredient and strength and is listed from ₹65 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Spiromide cost on PingMeDoc Pharmacy?
Spiromide starts at ₹72 (MRP ₹76) on PingMeDoc Pharmacy. Available in NA 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Spiromide?
Spiromide is manufactured by RPG LIFE SCIENCES LIMITED. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Spiromide delivered?
Spiromide is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Spiromide, Quick facts

Salt
Furosemide (20mg) + Spironolactone (50mg)
Best price
₹72
MRP
₹76
Prescription
Required (Rx)
Schedule
Schedule H
Brand
RPG LIFE SCIENCES LIMITED
Manufacturer
RPG LIFE SCIENCES LIMITED
Therapeutic class
CARDIAC
Drug class
Water tablet and Potassium-sparing diuretic
Habit forming
No
Variants
NA 10`S
Delivery
Standard across India

References

The information on Spiromide is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Spiromide.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.