Tenovate M Cream

Composition of Tenovate M Cream

Tenovate M Cream contains Clobetasol (0.05% w/w) + Miconazole (2% w/w). It belongs to the Very potent topical corticosteroid (clobetasol) + Imidazole antifungal (miconazole) class of medicines.

Uses of Tenovate M Cream

• Treatment of fungal skin infections with associated inflammation/itching such as tinea (ringworm)
• athlete’s foot (tinea pedis)
• jock itch (tinea cruris)
• and cutaneous candidiasis when significant redness and itching are present.

Key benefits

• Relieves itching and redness
• Reduces inflammation in fungal rashes
• Treats dermatophyte and yeast skin infections
• Helps improve comfort and healing of infected skin

How Tenovate M Cream works

Clobetasol propionate is a very potent topical corticosteroid that reduces inflammation, redness and itching by suppressing local inflammatory mediators. Miconazole is an imidazole antifungal that damages fungal cell membranes by inhibiting ergosterol synthesis, stopping fungal growth.

How to take Tenovate M Cream

For external use only. Clean and dry the affected area, then apply a thin layer to the affected skin 1–2 times daily or as prescribed. Avoid covering with occlusive dressings unless advised. Use for the shortest duration needed; do not apply on face, groin, armpits, broken skin, or large areas unless prescribed.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Tenovate-M Cream, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can suppress the body's own steroid production when it is used for a long time over large areas, especially in children. It is unlikely from skin use; swallowing the preparation may cause stomach upset. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Tenovate M Cream

Most side effects of Tenovate M are mild and settle as the body adjusts. Reported side effects include:

• Burning
• stinging
• itching
• dryness
• redness
• irritation
• skin thinning (atrophy)
• stretch marks
• acneiform eruptions
• hypopigmentation
• increased hair growth
• secondary infection

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Tenovate M Cream

Warnings and precautions

Schedule H: use only on prescription. Do not use for viral skin infections (herpes, chickenpox), tuberculosis of skin, untreated bacterial infections, or on open wounds. Prolonged or extensive use (especially under occlusion) can cause systemic corticosteroid effects (adrenal suppression, Cushingoid features), particularly in children. Avoid eyes and mucous membranes. Stop and seek medical advice if worsening, severe irritation, or no improvement within 1–2 weeks; antifungal therapy alone may be preferred once inflammation settles.

Do not take Tenovate M if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for untreated bacterial, fungal or viral skin infections. Not for use in or around the eyes. For external use only. Not for use in the eyes.

Interactions with other medicines

No major systemic interactions expected with topical use, but increased steroid absorption with occlusive dressings or use with other topical corticosteroids. Topical miconazole may rarely enhance anticoagulant effect of warfarin if significant absorption occurs; use caution in patients on anticoagulants when used over large areas/prolonged.

How to store Tenovate M Cream

Store below 25°C. Keep the tube tightly closed. Protect from heat and direct light. Do not freeze.

Expert advice for Tenovate M Cream

Tenovate-M Cream must be applied as a thin layer on the affected area as prescribed by your doctor. Do not use this medicine more often or for longer than advised by your doctor. Before each application, wash the affected area with soap and water and dry well. Avoid getting it in the eyes, mouth or nose. Rinse with cold water if you accidentally get it in these areas. Do not cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects. Inform your doctor if the treated skin area does not improve after 2-4 weeks of treatment.

Manufacturer and class

Manufacturer:

Glaxo SmithKline Pharmaceuticals Ltd

Therapeutic class:

Dermatological (Topical corticosteroid + Antifungal)

Drug class:

Very potent topical corticosteroid (clobetasol) + Imidazole antifungal (miconazole)