Trajenta 5 Tablet

Composition of Trajenta 5 Tablet

Trajenta 5 Tablet contains Linagliptin (5mg). It belongs to the DPP-4 inhibitor (gliptin) class of medicines.

Uses of Trajenta 5 Tablet

• Type 2 diabetes mellitus: used to improve blood sugar control in adults
• as monotherapy or in combination with other antidiabetic medicines along with diet and exercise.

Key benefits

• Lowers HbA1c and fasting/post-meal glucose
• Once-daily convenient dosing
• Low hypoglycaemia risk when used alone
• Weight-neutral glucose control
• Can be used in renal impairment without routine dose adjustment

How Trajenta 5 Tablet works

Linagliptin is a DPP-4 inhibitor that increases incretin hormones (GLP-1, GIP) by preventing their breakdown. This increases insulin release in a glucose-dependent manner and reduces glucagon secretion, lowering blood glucose with a low risk of hypoglycaemia when used alone.

How to take Trajenta 5 Tablet

Oral tablet: typically 1 tablet (5 mg) once daily, with or without food, at the same time each day. Swallow whole with water; continue diet and exercise as advised. Dose adjustments may be needed when used with insulin or sulfonylureas to reduce hypoglycaemia risk.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Trajenta 5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine may cause low blood sugar, particularly if you also take other diabetes medicines. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Trajenta 5 Tablet

Most side effects of Trajenta are mild and settle as the body adjusts. Reported side effects include:

• Nasopharyngitis
• cough
• sore throat
• headache
• diarrhoea
• rash
• hypoglycaemia (especially with insulin/sulfonylureas)
• constipation
• dizziness

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Trajenta 5 Tablet

Warnings and precautions

Not for type 1 diabetes or diabetic ketoacidosis. Use caution in patients with history of pancreatitis; stop and seek medical help if severe persistent abdominal pain occurs. Rare serious hypersensitivity reactions (angioedema, anaphylaxis) and severe skin reactions (bullous pemphigoid) may occur; discontinue if suspected. Monitor for joint pain and signs of heart failure when used with other agents as clinically indicated. In renal impairment, linagliptin generally does not require dose adjustment; follow prescriber advice.

Do not take Trajenta if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis.

Interactions with other medicines

Insulin and sulfonylureas (increased hypoglycaemia risk), strong CYP3A4/P-gp inducers such as rifampicin, carbamazepine, phenytoin, phenobarbital, St John’s wort (may reduce linagliptin effect), other antidiabetic drugs (additive glucose-lowering)

How to store Trajenta 5 Tablet

Store below 30°C in a dry place. Protect from moisture and direct light. Keep out of reach of children.

Expert advice for Trajenta 5 Tablet

Trajenta 5mg Tablet should be taken at the same time every day since this helps you remember to take it. It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines or alcohol, or if you delay or miss a meal. Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremors, and anxiety. Be careful while driving or operating machinery until you know how Trajenta 5mg Tablet affects you. Inform your doctor if you notice joint pains or develop symptoms such as stomach pain, nausea, and/or vomiting.

Manufacturer and class

Manufacturer:

ELI LILLY AND COMPANY PVT.LTD`

Therapeutic class:

Antidiabetic

Drug class:

DPP-4 inhibitor (gliptin)

Chemical class:

Xanthine derivative