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Prescription requiredAbbott India LimitedAntidiabetic

Tresiba Penfill

Insulin degludec 100 IU/mL solution for injection (3 mL cartridge)

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Tresiba Penfill is used for treatment of diabetes mellitus to improve glycaemic control in adults, adolescents and children (typically type 1 and type 2 diabetes) as a long-acting basal insulin.

Licensed pharmacyPharmacist-verified order

Key details

Salt: Insulin degludec 100 IU/mL solution for injection (3 mL cartridge)
Available variants: NA 5X3ML
Price: ₹7,200
Prescription: Required
Manufacturer: ABBOTT INDIA LTD

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Tresiba Penfill

Tresiba Penfill contains Insulin degludec 100 IU/mL solution for injection (3 mL cartridge). It belongs to the Long-acting (ultra-long) insulin analogue (basal insulin) class of medicines.

Uses of Tresiba Penfill

  • Diabetes mellitus to improve glycaemic control in adults
  • Adolescents
  • Children (typically type 1
  • Type 2 diabetes) as a long-acting basal insulin

Benefits of Tresiba Penfill

In Type 1 diabetes
Tresiba Penfill replaces the insulin a type 1 pancreas no longer makes. It is what allows the body to use food for energy, and keeping sugar in range with it prevents both the immediate danger of very high sugar and the long-term damage to eyes, kidneys and nerves.
In Type 2 diabetes
Tresiba Penfill brings blood sugar down when tablets alone no longer keep it in range, protecting the eyes, kidneys, nerves and heart from the damage of long-standing high sugar.

How Tresiba Penfill works

Insulin degludec is an ultra‑long acting basal insulin analogue. After subcutaneous injection it forms multi-hexamers that slowly release insulin, providing a stable, prolonged glucose-lowering effect for more than 24 hours.

How to take Tresiba Penfill

For subcutaneous use only in a compatible insulin pen using Penfill cartridges. Inject once daily at the same time each day or, if needed, with flexible timing as advised by the doctor. Can be taken with or without food; rotate injection sites (abdomen, thigh, upper arm). Do not mix with other insulins in the same syringe/cartridge; not for IV use.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Contact your doctor or diabetes nurse for advice — do not take a double dose to make up for a missed injection.

If you take too much

An overdose of this medicine can cause severe low blood sugar, leading to fits or unconsciousness — this is a medical emergency. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Tresiba Penfill

Most side effects of Tresiba Penfill are mild and settle as the body gets used to the medicine. The ones reported most often are:

  • Hypoglycaemia
  • injection site reactions (pain/redness/swelling)
  • weight gain
  • oedema
  • lipodystrophy (lipoatrophy/lipohypertrophy)
  • rash
  • pruritus

Stop the medicine and get help at once for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Tresiba Penfill

AlcoholCAUTION
Use with caution (may increase risk of hypoglycaemia)
PregnancyCONSULT YOUR DOCTOR
Consult doctor (insulin is used in pregnancy; dose adjustments and close monitoring required)
Breast feedingSAFE
Generally considered safe while breastfeeding.
DrivingCAUTION
May cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
KidneyCAUTION
Use with caution if you have kidney disease. Your doctor may adjust the dose or monitor your kidney function.
LiverCAUTION
Use with caution if you have liver disease. Your doctor may adjust the dose or monitor your liver function.

Warnings and precautions

Risk of hypoglycaemia (may impair driving/operating machinery); dose adjustments needed with changes in diet/exercise, intercurrent illness, renal/hepatic impairment. Do not use during episodes of hypoglycaemia. Avoid medication errors (confirm insulin name/strength); do not share pens/needles. Monitor for allergic reactions and injection-site lipodystrophy; rotate sites. Use with caution when switching from other insulins—requires close glucose monitoring.

Do not take Tresiba Penfill if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not to be used during an episode of low blood sugar.

Interactions with other medicines

Other antidiabetics (sulfonylureas, glinides) increase hypoglycaemia risk; beta-blockers may mask hypoglycaemia; corticosteroids, thiazide diuretics, thyroid hormones, sympathomimetics and danazol may increase glucose and insulin needs; ACE inhibitors, MAO inhibitors, salicylates and alcohol may enhance hypoglycaemic effect; pioglitazone with insulin may increase risk of fluid retention/heart failure.

How to store Tresiba Penfill

Unopened: store refrigerated at 2–8°C, do not freeze; keep away from freezer compartment. In-use: may be kept at room temperature (generally below 30°C) or refrigerated as per label; protect from heat and direct light; keep cartridge in carton; discard if frozen or if solution is not clear/colorless.

Quick tips for Tresiba Penfill

  • Keep an unopened supply in the fridge and the pen in use at room temperature, away from direct sunlight.
  • Always carry a fast-acting sugar source.
  • Check your sugar as your doctor has instructed, and keep a record to take to appointments.

People taking Tresiba Penfill are often asked to check these from time to time. Your doctor decides which and how often.

Manufacturer and class

Manufacturer:
ABBOTT INDIA LTD
Therapeutic class:
Antidiabetic
Drug class:
Long-acting (ultra-long) insulin analogue (basal insulin)

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Tresiba Penfill FAQs

What is Tresiba Penfill used for?
Tresiba Penfill is commonly used for Treatment of diabetes mellitus to improve glycaemic control in adults, adolescents and children (typically type 1 and type 2 diabetes) as a long-acting basal insulin. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What are the benefits of Tresiba Penfill?
Type 1 diabetes: Tresiba Penfill replaces the insulin a type 1 pancreas no longer makes. It is what allows the body to use food for energy, and keeping sugar in range with it prevents both the immediate danger of very high sugar and the long-term damage to eyes, kidneys and nerves. It is also used for type 2 diabetes.
What is the salt in Tresiba Penfill?
Tresiba Penfill contains Insulin degludec 100 IU/mL solution for injection (3 mL cartridge). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Tresiba Penfill?
For subcutaneous use only in a compatible insulin pen using Penfill cartridges. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Tresiba Penfill work?
Insulin degludec is an ultra‑long acting basal insulin analogue.
Is Tresiba Penfill a prescription medicine?
Yes. Tresiba Penfill is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Tresiba Penfill?
The side effects reported most often with Tresiba Penfill are Hypoglycaemia, injection site reactions (pain/redness/swelling), weight gain, oedema, lipodystrophy (lipoatrophy/lipohypertrophy). Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Tresiba Penfill be taken during pregnancy?
Consult your doctor before taking Tresiba Penfill in pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Tresiba Penfill.
Can I drink alcohol while taking Tresiba Penfill?
Limit alcohol while taking Tresiba Penfill; it can worsen the side effects.
What if I miss a dose of Tresiba Penfill?
Contact your doctor or diabetes nurse for advice — do not take a double dose to make up for a missed injection.
Is Tresiba Penfill habit forming?
No. Tresiba Penfill is not known to be habit forming when taken as prescribed.
How much does Tresiba Penfill cost on PingMeDoc Pharmacy?
Tresiba Penfill starts at ₹7,200 on PingMeDoc Pharmacy. Available in NA 5X3ML. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Tresiba Penfill?
Tresiba Penfill is manufactured by ABBOTT INDIA LTD. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Tresiba Penfill delivered?
Tresiba Penfill is delivered across India from our licensed pharmacy. Orders placed before 2 pm ship the same day, later ones the next day, every day of the week. Chennai: next-day delivery by Porter, ₹99 (free above ₹1,499). Enter your pincode on the page to see the date it reaches you.

Tresiba Penfill, Quick facts

Salt
Insulin degludec 100 IU/mL solution for injection (3 mL cartridge)
Price
₹7,200
Prescription
Required (Rx)
Schedule
Schedule H
Brand
Abbott India Limited
Manufacturer
ABBOTT INDIA LTD
Therapeutic class
Antidiabetic
Drug class
Long-acting (ultra-long) insulin analogue (basal insulin)
Habit forming
No
Variants
NA 5X3ML
Delivery
Standard across India

References

Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered pharmacist. It does not replace your own doctor's advice.

  1. Manufacturer labeling/SmPC, established medical literature on insulin degludec
  2. Indian drug regulatory/market labeling practices (CDSCO where applicable)
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Tresiba Penfill.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.