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Tolvaptan (15mg)
Vaptan Tablet is used for syndrome of inappropriate antidiuretic hormone secretion (SIADH) Treatment of Low levels of sodium in the blood.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Medicines with the same active ingredient and strength as Vaptan Tablet.
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Vaptan Tablet
tablet - 10 S
₹980
₹97.97 per tablet
CENTAUR PHARMACEUTICALS LTD` · tablet - 15 mg - 10 S · Rx
₹536
₹53.64 per tablet
ZYDUS HEALTHCARE PHARMA · tablet - 10 S · Rx
₹806
₹80.60 per tablet
BIOKINDLE · tablet - 15 mg - 10 S · Rx
₹890
₹89.02 per tablet
A substitute contains the same active ingredient (salt), in the same strength, as Vaptan Tablet. The medicine inside is the same — the brand name, manufacturer and price are what differ.
All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.
Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.
Vaptan Tablet contains Tolvaptan (15mg). It belongs to the Water tablet class of medicines.
Syndrome of inappropriate antidiuretic hormone secretion (SIADH) Treatment of Low levels of sodium in the blood
Vaptan Tablet is a vasopressin antagonist. It works by blocking the effect of the hormone vasopressin in the body. This increases urine production, reduces the amount of water in the blood and raises the blood sodium level.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Vaptan Tablet may be taken with or without food.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you miss a dose of Vaptan Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
An overdose of this medicine can cause severe dehydration, a sharp fall in blood pressure and dangerous salt imbalances. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Vaptan are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Consult doctor |
|---|---|
| Breastfeeding | Breast feeding UNSAFE |
| Alcohol | Use with caution |
| Driving | Driving UNSAFE |
| Kidney | Kidney CAUTION |
| Liver | Liver CAUTION |
| Habit forming | No |
Take it in the morning so that passing urine does not disturb your sleep. Your doctor will check your salts and kidney function with blood tests — do not skip them. Report muscle cramps, marked weakness, confusion or an irregular heartbeat; these can be signs your potassium or sodium has fallen. In hot weather or during an illness with vomiting or loose motions, tell your doctor — you may become dehydrated quickly.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people who are unable to pass urine, or who are severely dehydrated.
Anti-inflammatory painkillers blunt the effect and can strain the kidneys. Lithium and digoxin levels are affected; tell your doctor if you take either. Potassium-sparing types must not be combined with potassium supplements without supervision.
Store at room temperature (below 25°C), protected from light and moisture. Keep out of reach of children.
Vaptan Tablet treats low sodium levels in the blood. It also improves urine flow without causing the body to lose too much sodium as you urinate. Take it at the same time everyday. Take it according to the dose and duration prescribed by your doctor. To avoid dehydration, it is best to drink something as soon as you feel thirsty, but avoid alcoholic drinks. Do not take Vaptan Tablet if you are unable to urinate, if you are unable to tell when you are thirsty, or if you are severely dehydrated. You will need to be in a hospital under observation any time you start or restart treatment with Vaptan Tablet. Inform your doctor if you notice problems with speech or muscle control, trouble swallowing, trouble moving your arms and legs, or mood changes. Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
Medicines with the same active ingredient (Tolvaptan (15mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Vaptan Tablet |
|---|---|---|---|
| Tvaptan 15 mg TabletCENTAUR PHARMACEUTICALS LTD` | tablet · 10`S | ₹536 | 45% cheaper |
| Tolvat 15 TabletMSN LABORATORIES | tablet · 4`S | ₹549 | 44% cheaper |
| Tolsama 15 TabletMSN LABORATORIES | tablet · 4`S | ₹611 | 38% cheaper |
| Hyponat O 15 TabletZYDUS HEALTHCARE PHARMA | tablet · 10`S | ₹806 | 18% cheaper |
| Vaptolva 15 mg TabletBIOKINDLE | tablet · 10`S | ₹890 | 9% cheaper |

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The information on Vaptan Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.