Skip to main content
PingMeDoc
Prescription requiredBiokindleDiuretic / Electrolyte disorder therapy (Aquaretic)

Vaptolva 15 mg Tablet

Tolvaptan 15 mg

₹890MRP ₹9375% offIn stock
Order on WhatsApp

Delivered across India in about 3–5 days, Chennai next day. ₹49 delivery, free above ₹999.

Cash on delivery available — pay when your order arrives

This medicine needs a prescription.

You can pay now and add the prescription afterwards. We pack your order only after a pharmacist verifies it.

Upload prescriptionNo prescription? A doctor will call you (free)

A doctor decides whether a prescription can be issued. If it is not issued, the prescription items in your order are cancelled and refunded. You choose this at checkout.

Vaptolva 15 mg Tablet is used for treatment of clinically significant hypervolemic and euvolemic hyponatremia (low sodium) associated with conditions such as heart failure, cirrhosis and SIADH (syndrome of inappropriate antidiuretic hormone secretion), when fluid restriction is ineffective.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Tolvaptan 15 mg
Available variants: tablet 15 mg 10`S
Best price: ₹890 (₹89.02 per tablet)
MRP: ₹937
Prescription: Required
Manufacturer: BIOKINDLE

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Vaptolva 15 mg Tablet in Bangladesh

2 brands registered in Bangladesh with the same salt, strength and form.

  • Tolvan 15Eskayef Pharmaceuticals Ltd., Tongi,Gazipur
  • Vaptan 15Popular Pharmaceuticals PLC

Brand names differ between countries. Ask a pharmacist or your doctor in Bangladesh before switching. We don't sell or ship these brands. Source: Directorate General of Drug Administration, Bangladesh.

Same salt, lower price

Medicines with the same active ingredient and strength as Vaptolva 15 mg Tablet.

You are viewing

Vaptolva 15 mg Tablet

tablet - 15 mg - 10 S

₹890

₹89.02 per tablet

  • Tvaptan 15MG Tab

    CENTAUR PHARMACEUTICALS LTD` · tablet - 15 mg - 10 S · Rx

    ₹536

    ₹53.64 per tablet

    Save 40%
  • Hyponat O 15 Tab

    ZYDUS HEALTHCARE PHARMA · tablet - 15mg - 10 S · Rx

    ₹806

    ₹80.60 per tablet

Compare all substitutes
Same salt, different brand — what does that mean?

A substitute contains the same active ingredient (salt), in the same strength, as Vaptolva 15 mg Tablet. The medicine inside is the same — the brand name, manufacturer and price are what differ.

All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.

Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.

Composition of Vaptolva 15 mg Tablet

Vaptolva 15 mg Tablet contains Tolvaptan 15 mg. It belongs to the Vasopressin V2 receptor antagonist class of medicines.

Uses of Vaptolva 15 mg Tablet

  • Treatment of clinically significant hypervolemic and euvolemic hyponatremia (low sodium) associated with conditions such as heart failure
  • cirrhosis and SIADH (syndrome of inappropriate antidiuretic hormone secretion)
  • when fluid restriction is ineffective.

Key benefits

  • Raises low sodium levels in hyponatremia
  • Promotes excretion of excess body water without major sodium loss
  • Helps relieve fluid overload in heart failure/cirrhosis-associated hyponatremia
  • Improves symptoms related to low sodium (confusion
  • weakness) under monitoring

How Vaptolva 15 mg Tablet works

Tolvaptan is a selective vasopressin V2-receptor antagonist in the kidney. It blocks the action of antidiuretic hormone (ADH), increasing free water excretion (aquaresis) without significant loss of sodium, thereby raising serum sodium levels and reducing fluid overload.

How to take Vaptolva 15 mg Tablet

Tablet to be taken by mouth exactly as prescribed. Commonly started and monitored by a doctor with regular sodium and liver-function checks; take at the same time each day, with or without food. Ensure adequate access to water and drink to thirst; do not restrict fluids unless advised.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause severe dehydration, a sharp fall in blood pressure and dangerous salt imbalances. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Vaptolva 15 mg Tablet

Most side effects of Vaptolva are mild and settle as the body adjusts. Reported side effects include:

  • Thirst
  • dry mouth
  • increased urination (polyuria)
  • frequent urination (pollakiuria)
  • nocturia
  • dehydration
  • dizziness
  • constipation
  • weakness
  • hypernatremia
  • increased liver enzymes

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Vaptolva 15 mg Tablet

PregnancyConsult doctor (use with caution; limited human data)
BreastfeedingConsult your doctor before using this while breastfeeding.
AlcoholUse with caution (may worsen dizziness/dehydration and affect fluid balance)
DrivingMay cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
KidneyConsult your doctor if you have kidney disease.
LiverConsult your doctor if you have liver disease.
Habit formingNo

Warnings and precautions

Prescription-only medicine. Risk of overly rapid correction of sodium (can cause serious neurological injury); requires close monitoring of serum sodium, especially at initiation and dose changes. Can cause serious liver injury—avoid in patients with underlying significant liver disease unless specifically indicated and monitor LFTs; stop and seek care for fatigue, anorexia, right upper abdominal pain, dark urine or jaundice. Avoid use in patients unable to sense/respond to thirst, in anuria, or needing urgent sodium correction. Use caution in dehydration, hypotension, and with concurrent diuretics. Not for routine use in mild/asymptomatic hyponatremia.

Do not take Vaptolva if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people who are unable to pass urine, or who are severely dehydrated.

Interactions with other medicines

Strong CYP3A inhibitors (ketoconazole, itraconazole, clarithromycin, ritonavir) increase levels—avoid/contraindicated; CYP3A inducers (rifampicin, carbamazepine, phenytoin, St John’s wort) reduce effect; grapefruit/grapefruit juice increases levels—avoid; other diuretics and drugs affecting sodium (loop/thiazide diuretics) increase risk of dehydration/electrolyte imbalance; digoxin levels may increase; caution with NSAIDs and lithium (fluid/electrolyte effects).

How to store Vaptolva 15 mg Tablet

Store below 25°C, in a cool dry place, protected from light and moisture. Keep out of reach of children.

Expert advice for Vaptolva 15 mg Tablet

Weigh yourself at the same time each day if you have heart failure, and report a rapid gain. Do not add extra salt, and ask before using a potassium-based salt substitute.

Manufacturer and class

Manufacturer:
BIOKINDLE
Therapeutic class:
Diuretic / Electrolyte disorder therapy (Aquaretic)
Drug class:
Vasopressin V2 receptor antagonist

Substitutes for Vaptolva 15 mg Tablet

Medicines with the same active ingredient (Tolvaptan 15 mg). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Vaptolva 15 mg Tablet
Tvaptan 15 mg TabletCENTAUR PHARMACEUTICALS LTD`tablet · 10`S₹53640% cheaper
Tolvat 15 TabletMSN LABORATORIEStablet · 4`S₹54938% cheaper
Tolsama 15 TabletMSN LABORATORIEStablet · 4`S₹61131% cheaper
Hyponat O 15 TabletZYDUS HEALTHCARE PHARMAtablet · 10`S₹8069% cheaper
Vaptan TabletSTEADFAST MEDISHIELDtablet · 10`S₹98010% more
See all substitutes and alternatives

More from Biokindle

View categories
Amigraf 0.25 Caps
Rx

Amigraf 0.25 Caps

Biokindle - Capsule - 0.25mg - 10 S

₹109₹114

Save ₹5

Prescription required

Amigraf 1 MG Caps
5% offRx

Amigraf 1 MG Caps

Biokindle - Capsule - 1 mg - 10 S

₹387₹407

Save ₹20

Prescription required

5% offRx

Amigraf 2MG Cap

Biokindle - Capsule - 2 mg - 10 S

₹784₹825

Save ₹41

Prescription required

Arkapres 100MCG Tab
7% offRx

Arkapres 100MCG Tab

Biokindle - Tablet - 100 mcg - 10 S

₹13₹14

Save ₹1

Prescription required

Dibnepan Cap
5% offRx

Dibnepan Cap

Biokindle - Capsule - 300mg + 12.5mg + 2.5mg - 10 S

₹318₹335

Save ₹17

Prescription required

Farokindle 200MG Tab
5% offRx

Farokindle 200MG Tab

Biokindle - Tablet - 200 mg - 6 S

₹490₹516

Save ₹26

Prescription required

Febudim 40MG Tab
5% offRx

Febudim 40MG Tab

Biokindle - Tablet - 40 mg - 10 S

₹102₹107

Save ₹5

Prescription required

Febudim Er 40MG Tab
5% offRx

Febudim Er 40MG Tab

Biokindle - Tablet - 40 mg - 10 S

₹142₹149

Save ₹7

Prescription required

More in Diuretics

View categories
Acetamide 250
5% offRx

Acetamide 250

Micro Labs - 10 S

₹41₹43

Save ₹2

Prescription required

Aldactone T 10MG Tab
5% offRx

Aldactone T 10MG Tab

Rpg Life Sciences Limited - Tablet - 10 mg - 15 S

₹105₹111

Save ₹6

Prescription required

Aquazide 12.5 Tablet
9% offRx

Aquazide 12.5 Tablet

Sun Pharma - Tablet - 10 Tablet

₹10₹11

Save ₹1

Prescription required

Aquazide 25 Tablet
11% offRx

Aquazide 25 Tablet

Sun Pharma - Tablet - 10 Tablet

₹17₹19

Save ₹2

Prescription required

10% offRx

Arkamin H Tablet

Torrent Pharmaceuticals Ltd - Tablet - 10 Tablet

₹26₹29

Save ₹3

Prescription required

Avva SR Cap
6% offRx

Avva SR Cap

Intas Pharmaceuticals Ltd - Capsule - 250mg - 10 S

₹51₹54

Save ₹3

Prescription required

Benidin 4MG Tab
6% offRx

Benidin 4MG Tab

Lloyd Healthcare - Tablet - 4 mg - 15

₹116₹123

Save ₹7

Prescription required

Ctd 12.5MG Tab
5% offRx

Ctd 12.5MG Tab

IPCA Laboratories Ltd - Tablet - 12.5 mg - 15 S

₹152₹160

Save ₹8

Prescription required

Popular on PingMeDoc Pharmacy

View categories
Zincolife Syrup
11% offRxOut of stock

Zincolife Syrup

Mankind (Pharma) - Syrup - 50 ml

₹76₹85

Save ₹9

Prescription required

Zerolac Powder

Zerolac Powder

Raptokos & Brett - Powder - 400 G

₹308
14% offRx

Zedott Baby Sachet

Torrent Pharmaceuticals Ltd - Powder - 1 G

₹19₹22

Save ₹3

Prescription required

Xyzal Syrup
10% off

Xyzal Syrup

Dr Reddys Laboratories Ltd - Syrup - 60 ml

₹167₹186

Save ₹19

Zeepam Injection
Rx

Zeepam Injection

Tamman Titoe Pharma Pvt Ltd - Injection - 2 ml

₹12

Prescription required

Available in store

In-store
Xyzal Nasal Spray
10% offRx

Xyzal Nasal Spray

Dr Reddys Laboratories Ltd - Spray - 6 G

₹529₹588

Save ₹59

Prescription required

Yaskin-G
10% offOut of stock

Yaskin-G

Villi & Puri Scientifica - Tablet - 15 G

₹305₹339

Save ₹34

Zenoxidil F Pro 10 Solution
10% offOut of stock

Zenoxidil F Pro 10 Solution

Not Available - Solution - 60 ml

₹928₹1,031

Save ₹103

Vaptolva 15 mg Tablet FAQs

What is Vaptolva 15 mg Tablet used for?
Vaptolva 15 mg Tablet is commonly used for Treatment of clinically significant hypervolemic and euvolemic hyponatremia (low sodium) associated with conditions such as heart failure, cirrhosis and SIADH (syndrome of inappropriate antidiuretic hormone secretion), when fluid restriction is ineffective. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Vaptolva 15 mg Tablet?
Vaptolva 15 mg Tablet contains Tolvaptan 15 mg. If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Vaptolva 15 mg Tablet?
Tablet to be taken by mouth exactly as prescribed. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Vaptolva 15 mg Tablet work?
Tolvaptan is a selective vasopressin V2-receptor antagonist in the kidney.
Is Vaptolva 15 mg Tablet a prescription medicine?
Yes. Vaptolva 15 mg Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Vaptolva 15 mg Tablet?
The side effects reported most often with Vaptolva are Thirst, dry mouth, increased urination (polyuria), frequent urination (pollakiuria), nocturia. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Vaptolva 15 mg Tablet be taken during pregnancy?
Consult doctor (use with caution; limited human data) Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Vaptolva.
Can I drink alcohol while taking Vaptolva 15 mg Tablet?
Use with caution (may worsen dizziness/dehydration and affect fluid balance)
What if I miss a dose of Vaptolva 15 mg Tablet?
Take it as soon as you remember.
Is Vaptolva 15 mg Tablet habit forming?
No. Vaptolva 15 mg Tablet is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Vaptolva 15 mg Tablet?
Tvaptan 15 mg Tablet has the same active ingredient and strength and is listed from ₹536 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Vaptolva 15 mg Tablet cost on PingMeDoc Pharmacy?
Vaptolva 15 mg Tablet starts at ₹890 (MRP ₹937) on PingMeDoc Pharmacy. Available in tablet 15 mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Vaptolva 15 mg Tablet?
Vaptolva 15 mg Tablet is manufactured by BIOKINDLE. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Vaptolva 15 mg Tablet delivered?
Vaptolva 15 mg Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Vaptolva 15 mg Tablet, Quick facts

Salt
Tolvaptan 15 mg
Form
tablet
Best price
₹890 (₹89.02 per tablet)
MRP
₹937
Prescription
Required (Rx)
Brand
BIOKINDLE
Manufacturer
BIOKINDLE
Therapeutic class
Diuretic / Electrolyte disorder therapy (Aquaretic)
Drug class
Vasopressin V2 receptor antagonist
Habit forming
No
Variants
tablet 15 mg 10`S
Delivery
Standard across India

References

Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.

  1. Manufacturer labeling, established medical literature
  2. FDA/EMA prescribing information
  3. Indian drug references/clinical guidelines
  4. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  5. National List of Essential Medicines (NLEM) 2022, Government of India.
  6. Manufacturer's package insert / prescribing information for Vaptolva 15 mg Tablet.
  7. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.