
Amigraf 0.25 Caps
Biokindle - Capsule - 0.25mg - 10 S
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Tolvaptan 15 mg
Delivered across India in about 3–5 days, Chennai next day. ₹49 delivery, free above ₹999.
Cash on delivery available — pay when your order arrives
This medicine needs a prescription.
You can pay now and add the prescription afterwards. We pack your order only after a pharmacist verifies it.
A doctor decides whether a prescription can be issued. If it is not issued, the prescription items in your order are cancelled and refunded. You choose this at checkout.
Vaptolva 15 mg Tablet is used for treatment of clinically significant hypervolemic and euvolemic hyponatremia (low sodium) associated with conditions such as heart failure, cirrhosis and SIADH (syndrome of inappropriate antidiuretic hormone secretion), when fluid restriction is ineffective.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
2 brands registered in Bangladesh with the same salt, strength and form.
Brand names differ between countries. Ask a pharmacist or your doctor in Bangladesh before switching. We don't sell or ship these brands. Source: Directorate General of Drug Administration, Bangladesh.
Medicines with the same active ingredient and strength as Vaptolva 15 mg Tablet.
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Vaptolva 15 mg Tablet
tablet - 15 mg - 10 S
₹890
₹89.02 per tablet
CENTAUR PHARMACEUTICALS LTD` · tablet - 15 mg - 10 S · Rx
₹536
₹53.64 per tablet
ZYDUS HEALTHCARE PHARMA · tablet - 15mg - 10 S · Rx
₹806
₹80.60 per tablet
A substitute contains the same active ingredient (salt), in the same strength, as Vaptolva 15 mg Tablet. The medicine inside is the same — the brand name, manufacturer and price are what differ.
All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.
Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.
Vaptolva 15 mg Tablet contains Tolvaptan 15 mg. It belongs to the Vasopressin V2 receptor antagonist class of medicines.
Tolvaptan is a selective vasopressin V2-receptor antagonist in the kidney. It blocks the action of antidiuretic hormone (ADH), increasing free water excretion (aquaresis) without significant loss of sodium, thereby raising serum sodium levels and reducing fluid overload.
Tablet to be taken by mouth exactly as prescribed. Commonly started and monitored by a doctor with regular sodium and liver-function checks; take at the same time each day, with or without food. Ensure adequate access to water and drink to thirst; do not restrict fluids unless advised.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause severe dehydration, a sharp fall in blood pressure and dangerous salt imbalances. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Vaptolva are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Consult doctor (use with caution; limited human data) |
|---|---|
| Breastfeeding | Consult your doctor before using this while breastfeeding. |
| Alcohol | Use with caution (may worsen dizziness/dehydration and affect fluid balance) |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Consult your doctor if you have kidney disease. |
| Liver | Consult your doctor if you have liver disease. |
| Habit forming | No |
Prescription-only medicine. Risk of overly rapid correction of sodium (can cause serious neurological injury); requires close monitoring of serum sodium, especially at initiation and dose changes. Can cause serious liver injury—avoid in patients with underlying significant liver disease unless specifically indicated and monitor LFTs; stop and seek care for fatigue, anorexia, right upper abdominal pain, dark urine or jaundice. Avoid use in patients unable to sense/respond to thirst, in anuria, or needing urgent sodium correction. Use caution in dehydration, hypotension, and with concurrent diuretics. Not for routine use in mild/asymptomatic hyponatremia.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people who are unable to pass urine, or who are severely dehydrated.
Strong CYP3A inhibitors (ketoconazole, itraconazole, clarithromycin, ritonavir) increase levels—avoid/contraindicated; CYP3A inducers (rifampicin, carbamazepine, phenytoin, St John’s wort) reduce effect; grapefruit/grapefruit juice increases levels—avoid; other diuretics and drugs affecting sodium (loop/thiazide diuretics) increase risk of dehydration/electrolyte imbalance; digoxin levels may increase; caution with NSAIDs and lithium (fluid/electrolyte effects).
Store below 25°C, in a cool dry place, protected from light and moisture. Keep out of reach of children.
Weigh yourself at the same time each day if you have heart failure, and report a rapid gain. Do not add extra salt, and ask before using a potassium-based salt substitute.
Medicines with the same active ingredient (Tolvaptan 15 mg). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Vaptolva 15 mg Tablet |
|---|---|---|---|
| Tvaptan 15 mg TabletCENTAUR PHARMACEUTICALS LTD` | tablet · 10`S | ₹536 | 40% cheaper |
| Tolvat 15 TabletMSN LABORATORIES | tablet · 4`S | ₹549 | 38% cheaper |
| Tolsama 15 TabletMSN LABORATORIES | tablet · 4`S | ₹611 | 31% cheaper |
| Hyponat O 15 TabletZYDUS HEALTHCARE PHARMA | tablet · 10`S | ₹806 | 9% cheaper |
| Vaptan TabletSTEADFAST MEDISHIELD | tablet · 10`S | ₹980 | 10% more |

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Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.