Vaptolva 15 mg Tablet

Composition of Vaptolva 15 mg Tablet

Vaptolva 15 mg Tablet contains Tolvaptan 15 mg. It belongs to the Vasopressin V2 receptor antagonist class of medicines.

Uses of Vaptolva 15 mg Tablet

• Treatment of clinically significant hypervolemic and euvolemic hyponatremia (low sodium) associated with conditions such as heart failure
• cirrhosis and SIADH (syndrome of inappropriate antidiuretic hormone secretion)
• when fluid restriction is ineffective.

Key benefits

• Raises low sodium levels in hyponatremia
• Promotes excretion of excess body water without major sodium loss
• Helps relieve fluid overload in heart failure/cirrhosis-associated hyponatremia
• Improves symptoms related to low sodium (confusion
• weakness) under monitoring

How Vaptolva 15 mg Tablet works

Tolvaptan is a selective vasopressin V2-receptor antagonist in the kidney. It blocks the action of antidiuretic hormone (ADH), increasing free water excretion (aquaresis) without significant loss of sodium, thereby raising serum sodium levels and reducing fluid overload.

How to take Vaptolva 15 mg Tablet

Tablet to be taken by mouth exactly as prescribed. Commonly started and monitored by a doctor with regular sodium and liver-function checks; take at the same time each day, with or without food. Ensure adequate access to water and drink to thirst; do not restrict fluids unless advised.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take the missed dose of Vaptolva as soon as you remember. If it is almost time for the next dose, skip the missed one and carry on with the usual schedule. Do not take two doses together to make up for a missed dose.

If you take too much

Taking more Vaptolva than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.

Side effects of Vaptolva 15 mg Tablet

Most side effects of Vaptolva are mild and settle as the body adjusts. Reported side effects include:

• Thirst
• dry mouth
• increased urination (polyuria)
• frequent urination (pollakiuria)
• nocturia
• dehydration
• dizziness
• constipation
• weakness
• hypernatremia
• increased liver enzymes

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Vaptolva 15 mg Tablet

Warnings and precautions

Prescription-only medicine. Risk of overly rapid correction of sodium (can cause serious neurological injury); requires close monitoring of serum sodium, especially at initiation and dose changes. Can cause serious liver injury—avoid in patients with underlying significant liver disease unless specifically indicated and monitor LFTs; stop and seek care for fatigue, anorexia, right upper abdominal pain, dark urine or jaundice. Avoid use in patients unable to sense/respond to thirst, in anuria, or needing urgent sodium correction. Use caution in dehydration, hypotension, and with concurrent diuretics. Not for routine use in mild/asymptomatic hyponatremia.

Interactions with other medicines

Strong CYP3A inhibitors (ketoconazole, itraconazole, clarithromycin, ritonavir) increase levels—avoid/contraindicated; CYP3A inducers (rifampicin, carbamazepine, phenytoin, St John’s wort) reduce effect; grapefruit/grapefruit juice increases levels—avoid; other diuretics and drugs affecting sodium (loop/thiazide diuretics) increase risk of dehydration/electrolyte imbalance; digoxin levels may increase; caution with NSAIDs and lithium (fluid/electrolyte effects).

How to store Vaptolva 15 mg Tablet

Store below 25°C, in a cool dry place, protected from light and moisture. Keep out of reach of children.

Manufacturer and class

Manufacturer:

BIOKINDLE

Therapeutic class:

Diuretic / Electrolyte disorder therapy (Aquaretic)

Drug class:

Vasopressin V2 receptor antagonist