Vildamac Trio 500 Tablet

Composition of Vildamac Trio 500 Tablet

Vildamac Trio 500 Tablet contains Dapagliflozin (10mg) + Metformin (500mg) + Vildagliptin (100mg). It belongs to the DPP-4 inhibitor + Biguanide + SGLT2 inhibitor class of medicines.

Uses of Vildamac Trio 500 Tablet

• Type 2 diabetes mellitus (T2DM) in adults
• as an add-on to diet and exercise when dual therapy is inadequate; helps improve glycaemic control (fasting and post-meal glucose
• HbA1c).

Key benefits

• Lowers HbA1c
• controls fasting and post-meal blood sugar
• low hypoglycaemia risk when not combined with insulin/SU
• may aid weight reduction due to SGLT2 component
• once-daily convenient triple therapy

How Vildamac Trio 500 Tablet works

Vildagliptin (a DPP-4 inhibitor) increases incretin levels, enhancing glucose-dependent insulin release and reducing glucagon. Metformin reduces hepatic glucose production and improves insulin sensitivity. Dapagliflozin (an SGLT2 inhibitor) increases urinary glucose excretion by reducing renal glucose reabsorption.

How to take Vildamac Trio 500 Tablet

Oral tablet. Take exactly as prescribed, usually once daily with food (preferably with the main meal) to reduce stomach upset from metformin; swallow whole with water. Maintain adequate hydration; follow diet/exercise plan and monitor blood glucose as advised.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of VILDamac Trio 10mg/500mg/100mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause dehydration and a fall in blood pressure. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. It may cause low blood sugar, particularly if you also take other diabetes medicines. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Vildamac Trio 500 Tablet

Most side effects of Vildamac Trio are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• vomiting
• diarrhoea
• abdominal discomfort
• decreased appetite
• headache
• dizziness
• urinary tract infection
• genital fungal infection
• increased urination
• thirst
• nasopharyngitis

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Vildamac Trio 500 Tablet

Warnings and precautions

For prescription use only. Not for type 1 diabetes or diabetic ketoacidosis. Metformin may rarely cause lactic acidosis—risk increases with kidney impairment, dehydration, sepsis, heavy alcohol use, or hypoxia; stop and seek urgent care if severe weakness, fast breathing, abdominal pain or drowsiness occur. Dapagliflozin can cause dehydration/low BP, genital mycotic infections, UTIs and rare euglycaemic ketoacidosis—seek care for nausea/vomiting, abdominal pain, rapid breathing. Assess renal function before and during therapy; avoid/adjust in significant renal impairment. Withhold temporarily during acute illness, reduced intake, major surgery, or before iodinated contrast procedures as advised. Monitor for hypoglycaemia when used with insulin or sulfonylureas.

Do not take Vildamac Trio if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.

Interactions with other medicines

Insulin and sulfonylureas (increased hypoglycaemia risk), diuretics (increased dehydration/hypotension), ACE inhibitors/ARBs/NSAIDs (may affect renal function), iodinated contrast media (metformin—lactic acidosis risk; hold as per guidelines), alcohol (metformin—lactic acidosis risk), carbonic anhydrase inhibitors like topiramate/acetazolamide (metabolic acidosis risk), cationic drugs affecting renal tubular secretion such as cimetidine (may increase metformin levels)

How to store Vildamac Trio 500 Tablet

Store below 25°C in a cool, dry place. Protect from moisture and direct light. Keep out of reach of children.

Expert advice for Vildamac Trio 500 Tablet

Your doctor will monitor your blood sugar levels regularly when you are taking VILDamac Trio 10mg/500mg/100mg Tablet. Hypoglycemia (low blood sugar level) may occur when VILDamac Trio 10mg/500mg/100mg Tablet is taken along with other antidiabetic medicines, alcohol, or on delaying/skipping a meal. Check your blood sugar levels and have a snack/sugar source for immediate relief. If you get unusually thirsty, pass urine more frequently, and feel tired, let your doctor know. These are the signs of too much sugar in your blood and your dose may need adjusting. Lifestyle changes like a low-fat and salt diet, exercise, not smoking, and cutting down on the amount of alcohol you usually drink may help this medication work better.

Manufacturer and class

Manufacturer:

MACLEODS PHARMACEUTICALS LTD

Therapeutic class:

Antidiabetic

Drug class:

DPP-4 inhibitor + Biguanide + SGLT2 inhibitor