Vildaray M Plus

Composition of Vildaray M Plus

Vildaray M Plus contains Metformin (500mg) + Vildagliptin (50mg). It belongs to the DPP-4 inhibitor + Biguanide class of medicines.

Uses of Vildaray M Plus

Type 2 diabetes mellitus (as an adjunct to diet and exercise) when glycaemic control is inadequate with metformin alone or when already treated with vildagliptin and metformin.

Key benefits

• Improves fasting and post-meal blood sugar control
• Helps reduce HbA1c
• Lowers hepatic glucose production and improves insulin sensitivity
• Low risk of hypoglycaemia when used without sulfonylureas/insulin
• Convenient combination therapy to improve adherence

How Vildaray M Plus works

Vildagliptin is a DPP-4 inhibitor that increases incretin hormones (GLP-1, GIP), leading to increased insulin release and reduced glucagon in a glucose-dependent manner. Metformin reduces hepatic glucose production and improves insulin sensitivity, lowering blood glucose levels.

How to take Vildaray M Plus

Oral tablet. Take with food to reduce stomach upset; usually taken once or twice daily as prescribed. Swallow whole with water; do not crush/chew. Dose and schedule should be individualized based on blood sugar, kidney function and tolerance.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. It may cause low blood sugar, particularly if you also take other diabetes medicines. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Vildaray M Plus

Most side effects of Vildaray M Plus are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• vomiting
• diarrhoea
• abdominal pain
• loss of appetite
• headache
• dizziness
• tremor
• hypoglycaemia (especially with other antidiabetics)
• upper respiratory tract infection
• elevated liver enzymes

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Vildaray M Plus

Warnings and precautions

Prescription medicine. Risk of lactic acidosis with metformin (higher risk in severe kidney disease, dehydration, sepsis, hypoxia, excessive alcohol use); stop and seek urgent care if severe weakness, rapid breathing, abdominal pain or drowsiness occur. Check kidney function before and during therapy; not recommended in severe renal impairment. Monitor liver function with vildagliptin; discontinue if jaundice or persistent LFT elevation. Use caution in pancreatitis history; stop if severe persistent abdominal pain. Hold metformin on the day of iodinated contrast procedures and during major surgery as advised by doctor.

Do not take Vildaray M Plus if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis. Not for type 1 diabetes or for diabetic ketoacidosis.

Interactions with other medicines

Alcohol (increases lactic acidosis risk), iodinated contrast media, carbonic anhydrase inhibitors (e.g., topiramate/acetazolamide), cimetidine, diuretics, ACE inhibitors/ARBs (may affect glucose), corticosteroids, thiazide diuretics, sympathomimetics, other antidiabetics/insulin (increased hypoglycaemia risk)

How to store Vildaray M Plus

Store below 25°C in a cool, dry place. Protect from moisture and direct light. Keep in original blister pack and out of reach of children.

Expert advice for Vildaray M Plus

Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them. It can be taken with or without food, at the same time each day. Keep up your diet and activity — this medicine supports them.

Manufacturer and class

Manufacturer:

LLOYD HEALTHCARE

Therapeutic class:

Antidiabetic

Drug class:

DPP-4 inhibitor + Biguanide