Vildaprl M 500 Tablet

Composition of Vildaprl M 500 Tablet

Vildaprl M 500 Tablet contains Metformin (500mg) + Vildagliptin (50mg). It belongs to the DPP-4 inhibitor + Biguanide class of medicines.

Uses of Vildaprl M 500 Tablet

Type 2 diabetes mellitus; used to improve blood glucose control in adults when diet and exercise alone or single therapy is insufficient.

Key benefits

• Lowers fasting and post-meal blood glucose
• Improves insulin response in a glucose-dependent manner
• Reduces hepatic glucose production
• Helps improve HbA1c control
• Weight-neutral or minimal weight gain compared to some therapies

How Vildaprl M 500 Tablet works

Vildagliptin is a DPP-4 inhibitor that increases incretin levels, enhancing glucose-dependent insulin release and reducing glucagon secretion. Metformin decreases hepatic glucose production, reduces intestinal glucose absorption, and improves insulin sensitivity.

How to take Vildaprl M 500 Tablet

Oral tablet; take as prescribed, usually with meals to reduce stomach upset. Swallow whole with water; do not crush/chew. Regularly monitor blood glucose and follow diet/exercise advice.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Vildaprl M 500mg/50mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. It may cause low blood sugar, particularly if you also take other diabetes medicines. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Vildaprl M 500 Tablet

Most side effects of Vildaprl M are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• headache
• dizziness
• upper respiratory tract infection
• hypoglycaemia (more likely with other antidiabetics)
• metallic taste

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Vildaprl M 500 Tablet

Warnings and precautions

Not for type 1 diabetes or diabetic ketoacidosis. Metformin can rarely cause lactic acidosis—risk increases with kidney impairment, dehydration, heavy alcohol use, severe infection, hypoxia/heart failure, or liver disease; seek urgent care for rapid breathing, severe weakness, abdominal pain, or unusual sleepiness. Avoid/withhold around iodinated contrast procedures and major surgery as advised. Monitor kidney function before and during therapy; use caution in elderly. Stop and consult doctor if pancreatitis symptoms occur (severe persistent abdominal pain), or if signs of hypersensitivity or hepatitis/jaundice appear.

Do not take Vildaprl M if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis. Not for type 1 diabetes or for diabetic ketoacidosis.

Interactions with other medicines

Alcohol (increases lactic acidosis risk), iodinated contrast media, carbonic anhydrase inhibitors (e.g., topiramate, acetazolamide), cimetidine, diuretics, corticosteroids, thyroid hormones, sympathomimetics, rifampicin, ACE inhibitors, insulin/sulfonylureas (increased hypoglycaemia risk)

How to store Vildaprl M 500 Tablet

Store below 25°C in a cool, dry place. Protect from moisture and light. Keep out of reach of children.

Expert advice for Vildaprl M 500 Tablet

Take it in addition to regular exercise and a healthy diet to lower levels of blood sugar. Take it with food to lower your chance of having an upset stomach. Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain, as Vildaprl M 500mg/50mg Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood. Your doctor may check your kidney and liver function before starting treatment and regularly thereafter. Inform your doctor if you develop symptoms such as abdominal pain, fatigue, loss of appetite, darkened urine, or yellowing of the eyes or skin (jaundice).

Manufacturer and class

Manufacturer:

PRISTINE PEARL PHARMA

Therapeutic class:

Antidiabetic

Drug class:

DPP-4 inhibitor + Biguanide