Vildoff-M 50/500 mg Tablet

Composition of Vildoff-M 50/500 mg Tablet

Vildoff-M 50/500 mg Tablet contains Vildagliptin 50 mg + Metformin 500 mg (tablet). It belongs to the DPP-4 inhibitor + Biguanide class of medicines.

Uses of Vildoff-M 50/500 mg Tablet

• Type 2 diabetes mellitus (to improve blood glucose control along with diet and exercise)
• especially when blood sugar is not adequately controlled with metformin or other oral antidiabetic medicines

Key benefits

• Lowers fasting and post-meal blood sugar
• Improves insulin response in a glucose-dependent manner
• Helps reduce glucose production by the liver
• Low risk of hypoglycaemia when used without insulin/sulfonylureas
• Convenient combination therapy for type 2 diabetes

How Vildoff-M 50/500 mg Tablet works

Vildagliptin is a DPP-4 inhibitor that increases incretin hormones (GLP-1, GIP), leading to increased insulin release and reduced glucagon secretion in a glucose-dependent manner. Metformin decreases hepatic glucose production and improves insulin sensitivity, lowering blood glucose levels.

How to take Vildoff-M 50/500 mg Tablet

Oral tablet. Take as prescribed by a doctor, usually with meals to reduce stomach upset. Swallow whole with water; do not crush/chew. Regularly monitor blood glucose and follow diet/exercise advice.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine may cause low blood sugar, particularly if you also take other diabetes medicines. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Vildoff-M 50/500 mg Tablet

Most side effects of Vildoff-M 50/500 mg are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• metallic taste
• headache
• dizziness
• upper respiratory tract infection
• hypoglycaemia (more likely with other antidiabetics)
• increased liver enzymes

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Vildoff-M 50/500 mg Tablet

Warnings and precautions

Prescription-only antidiabetic. Metformin may rarely cause lactic acidosis—risk increases with kidney impairment, dehydration, heavy alcohol use, severe infection, heart/respiratory failure; stop and seek care if rapid breathing, severe weakness, abdominal pain occur. Use caution in renal impairment; dose adjustment/avoid based on eGFR. Vildagliptin may affect liver—check LFTs periodically and stop if persistent elevation or jaundice. Risk of pancreatitis—seek care for severe persistent abdominal pain. Temporarily withhold metformin before/after iodinated contrast or major surgery as advised. Not for type 1 diabetes or diabetic ketoacidosis.

Do not take Vildoff-M 50/500 mg if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.

Interactions with other medicines

Alcohol (increases lactic acidosis risk), iodinated contrast media (temporary stoppage needed), carbonic anhydrase inhibitors (e.g., topiramate, acetazolamide) may increase metabolic acidosis risk, cationic drugs affecting renal tubular secretion (e.g., cimetidine) may increase metformin levels, diuretics/ACE inhibitors/NSAIDs (may affect kidney function), corticosteroids and sympathomimetics (may raise glucose), insulin or sulfonylureas (increased hypoglycaemia risk)

How to store Vildoff-M 50/500 mg Tablet

Store below 25°C in a cool, dry place. Protect from moisture and direct light. Keep out of reach of children.

Expert advice for Vildoff-M 50/500 mg Tablet

It can be taken with or without food, at the same time each day. Keep up your diet and activity — this medicine supports them. Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them.

Manufacturer and class

Manufacturer:

SHAMAR PHARMACEUTICALS

Therapeutic class:

Antidiabetic

Drug class:

DPP-4 inhibitor + Biguanide