
Acuclav 375
Macleods Pharmaceuticals Pvt Ltd - 10 S
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Prescription required
Glimepiride (1mg) + Metformin (500mg) + Voglibose (0.3mg)
Currently out of stock
Same composition, in stock now. Check with your doctor or pharmacist before you switch.
Voglimac gm 1 Hd is used for type 2 diabetes mellitus: to improve blood glucose control in adults when diet and exercise are insufficient; helps reduce post-meal (postprandial) and fasting blood sugar.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Voglimac gm 1 Hd contains Glimepiride (1mg) + Metformin (500mg) + Voglibose (0.3mg). It belongs to the Alpha-glucosidase inhibitor + Biguanide (extended-release metformin) class of medicines.
Type 2 diabetes mellitus: to improve blood glucose control in adults when diet and exercise are insufficient; helps reduce post-meal (postprandial) and fasting blood sugar.
Voglibose is an alpha-glucosidase inhibitor that delays carbohydrate digestion and absorption in the intestine, lowering post-meal glucose spikes. Metformin (ER) reduces glucose production in the liver and improves insulin sensitivity, helping lower fasting and overall blood sugar.
Take exactly as prescribed. Usually taken with meals; voglibose works best when taken just before/with the first bite of food. Swallow the extended-release tablet whole; do not crush or chew. Regularly monitor blood glucose as advised.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you miss a dose of Voglimac GM 1 HD Tablet SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. It may cause low blood sugar and marked stomach upset. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Voglimac gm are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Consult doctor (generally not recommended unless clearly needed; insulin is preferred for diabetes in pregnancy) |
|---|---|
| Breastfeeding | Breast feeding UNSAFE |
| Alcohol | Avoid |
| Driving | Driving CONSULT YOUR DOCTOR |
| Kidney | Kidney UNSAFE |
| Liver | Liver UNSAFE |
| Habit forming | No |
For prescription use only. Metformin may rarely cause lactic acidosis—risk increases with severe kidney disease, dehydration, heavy alcohol use, severe infection, shock, or hypoxia; kidney function should be assessed before and during therapy. Temporarily stop metformin before/after iodinated contrast procedures and major surgery as advised by doctor. Use caution in liver disease, heart failure, and elderly. Risk of hypoglycaemia increases when used with insulin or sulfonylureas; recognize symptoms and treat promptly.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis. Not for people with heart failure, active bladder cancer or unexplained blood in the urine.
Alcohol (increases lactic acidosis risk), iodinated contrast media, insulin and sulfonylureas (increased hypoglycaemia risk), diuretics and ACE inhibitors/ARBs (may affect renal function), corticosteroids and thyroid hormones (may raise glucose), cationic drugs excreted by renal tubular secretion (e.g., cimetidine) may increase metformin levels
Store below 25°C in a dry place, protected from light and moisture. Keep in original blister pack and out of reach of children.
Voglimac GM 1 HD Tablet SR can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines or alcohol, or if you delay or miss a meal. Carry a sugar source with you for immediate relief. Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice). Individuals with severe renal or hepatic impairment should not take Voglimac GM 1 HD Tablet SR. This medicine works best when used along with proper diet and exercise.
Medicines with the same active ingredient (Glimepiride (1mg) + Metformin (500mg) + Voglibose (0.3mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Voglimac gm 1 Hd |
|---|---|---|---|
| Humiglim Mv 3.3 TabletVERSE LIFESCIENCES | tablet · 10`S | ₹142 | 12% more |
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| Volicure Trio 1 TabletHBC LIFESCEINCE PVT LTD | tablet · 15`S | ₹232 | 84% more |
| Volicure Trio 1/0.3 mg TabletHBC LIFESCEINCE PVT LTD | tablet · 15`S | ₹235 | 86% more |
| Azulix Mv 2/0.2 TabletTorrent Pharmaceuticals Ltd | tablet · 10`S | ₹247 | 96% more |

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The information on Voglimac gm 1 Hd is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.