Zavamet SR 1000 Tablet

Composition of Zavamet SR 1000 Tablet

Zavamet SR 1000 Tablet contains Metformin (1000mg) + Vildagliptin (50mg). It belongs to the Biguanide and DPP-4 inhibitor class of medicines.

Uses of Zavamet SR 1000 Tablet

Treatment of Type 2 diabetes mellitus

Key benefits

• In Treatment of Type 2 diabetes mellitus Zavamet SR 1000 Tablet is a combination of two medicines that work together in different ways to lower your blood glucose levels. Lowering blood glucose levels is an essential part of managing diabetes. If you can control your blood glucose level
• your risk of getting any of the serious complications of diabetes such as kidney damage
• eye damage
• nerve problems
• and loss of limbs is also lowered. Additionally
• proper control of diabetes can also reduce the risk of heart disease and stroke. Taking this medicine regularly along with proper diet and exercise will help you live a normal
• healthy life. You should keep using this medicine for as long as it is prescribed because it is protecting your future health.

How Zavamet SR 1000 Tablet works

Zavamet SR 1000 Tablet is a combination of two antidiabetic medicines: metformin and vildagliptin. Metformin is an anti-diabetic medication (biguanide). It works by lowering glucose production in the liver, delaying glucose absorption from the intestines, and increasing the body's sensitivity to insulin. Vildagliptin is a DPP-4 inhibitor that works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood sugar levels. This reduces both fasting and post-meal sugar levels. Together, they provide better control of blood sugar.

How to take Zavamet SR 1000 Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zavamet SR 1000 Tablet should be taken with or after food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Zavamet SR 1000 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. It may cause low blood sugar, particularly if you also take other diabetes medicines. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Zavamet SR 1000 Tablet

Most side effects of Zavamet SR are mild and settle as the body adjusts. Reported side effects include:

• Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Zavamet SR 1000 Tablet

Warnings and precautions

Stomach upset is common in the first two weeks and usually settles; taking it with food helps. Tell your doctor before any surgery or a scan that uses contrast dye — this medicine is usually stopped for a short time around them. Stop and seek urgent care if you develop deep rapid breathing, severe weakness, muscle pain or vomiting with cold clammy skin. This is rare but serious. Long-term use can lower vitamin B12, so your doctor may check it from time to time. Stop and see a doctor urgently if you get severe, persistent abdominal pain that spreads to your back, with or without vomiting. Tell your doctor if you develop severe or disabling joint pain. Blisters or peeling of the skin should be reported promptly.

Do not take Zavamet SR if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis. Not for type 1 diabetes or for diabetic ketoacidosis.

Interactions with other medicines

Tell your doctor about water tablets, steroids, and any contrast dye scan. Alcohol increases the risk of the rare acid build-up and should be limited. Low blood sugar is more likely when this is combined with a sulfonylurea or insulin; your doctor may lower that dose.

How to store Zavamet SR 1000 Tablet

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Zavamet SR 1000 Tablet

Take it in addition to regular exercise and a healthy diet to lower levels of blood sugar. Take it with food to lower your chance of having an upset stomach. Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain, as Zavamet SR 1000 Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood. Your doctor may check your kidney and liver function before starting treatment and regularly thereafter. Inform your doctor if you develop symptoms such as abdominal pain, fatigue, loss of appetite, darkened urine, or yellowing of the eyes or skin (jaundice).

Manufacturer and class

Manufacturer:

INTAS PHARMACEUTICALS`

Therapeutic class:

ANTI DIABETIC

Drug class:

Biguanide and DPP-4 inhibitor