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Prescription requiredDr Reddys Laboratories LtdCough & Cold Preparation (Antitussive/Expectorant/Decongestant)

Zedex-Sf

Dextromethorphan hydrobromide 10 mg + Guaifenesin 100 mg + Phenylephrine hydrochloride 5 mg per 5 ml

₹199MRP ₹209In stock
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Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.

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Zedex-Sf is used for symptomatic relief of dry or productive cough associated with common cold/upper respiratory tract infections; helps relieve chest congestion and nasal stuffiness.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Dextromethorphan hydrobromide 10 mg + Guaifenesin 100 mg + Phenylephrine hydrochloride 5 mg per 5 ml
Available variants: NA 100ML
Best price: ₹199 (₹1.99 per ml)
MRP: ₹209
Prescription: Required
Manufacturer: DR.REDDYS

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Zedex-Sf

Zedex-Sf contains Dextromethorphan hydrobromide 10 mg + Guaifenesin 100 mg + Phenylephrine hydrochloride 5 mg per 5 ml. It belongs to the Antitussive (NMDA receptor antagonist/central cough suppressant) + Expectorant + Sympathomimetic decongestant class of medicines.

Uses of Zedex-Sf

Symptomatic relief of dry or productive cough associated with common cold/upper respiratory tract infections; helps relieve chest congestion and nasal stuffiness.

Key benefits

  • Reduces cough frequency
  • Helps loosen and expel mucus
  • Relieves chest congestion
  • Reduces nasal congestion/stuffiness

How Zedex-Sf works

Dextromethorphan suppresses the cough reflex by acting on the cough center in the brain. Guaifenesin loosens and thins mucus to make coughing out phlegm easier. Phenylephrine is a decongestant that constricts nasal blood vessels to reduce swelling and congestion.

How to take Zedex-Sf

Oral syrup. Shake well before use and measure with a cup/spoon. Usually taken 2–3 times daily as advised by a doctor; may be taken with or without food. Do not exceed the recommended dose and avoid using multiple cough/cold products together.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause vomiting, severe drowsiness, a racing heart and, with codeine, dangerously slow breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Zedex-Sf

Most side effects of Zedex-Sf are mild and settle as the body adjusts. Reported side effects include:

  • Drowsiness
  • dizziness
  • nausea
  • vomiting
  • stomach upset
  • dry mouth
  • headache
  • nervousness
  • palpitations

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Zedex-Sf

PregnancyConsult doctor
BreastfeedingConsult your doctor before using this while breastfeeding.
AlcoholAvoid
DrivingMay cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
KidneyUse with caution if you have kidney disease — your doctor may adjust the dose or monitor your kidney function.
LiverUse with caution if you have liver disease — your doctor may adjust the dose or monitor your liver function.
Habit formingNo

Warnings and precautions

Use with caution in hypertension, heart disease, thyroid disorders, diabetes, glaucoma, enlarged prostate/urinary retention, liver disease and in the elderly. May cause drowsiness—avoid driving or operating machinery if affected. Do not use in children unless prescribed; avoid use with/within 14 days of MAO inhibitors. Seek medical advice if cough persists >7 days, is recurrent, or is accompanied by fever, rash, breathing difficulty, or thick green/yellow sputum.

Do not take Zedex-Sf if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Codeine-containing preparations are not for children, or for anyone with breathing difficulty.

Interactions with other medicines

MAO inhibitors (contraindicated), other serotonergic drugs (SSRIs/SNRIs/TCAs, linezolid) may increase risk of serotonin syndrome with dextromethorphan, alcohol and CNS depressants increase sedation, antihypertensives may have reduced effect with phenylephrine, other decongestants/sympathomimetics may increase BP/heart rate, beta-blockers may increase vasoconstrictive effects

How to store Zedex-Sf

Store below 25°C, protected from light and moisture. Keep bottle tightly closed and out of reach of children.

Expert advice for Zedex-Sf

Drink plenty of water — it thins mucus better than any syrup. Steam inhalation helps congestion and costs nothing. Measure the dose with the cup supplied.

Manufacturer and class

Manufacturer:
DR.REDDYS
Therapeutic class:
Cough & Cold Preparation (Antitussive/Expectorant/Decongestant)
Drug class:
Antitussive (NMDA receptor antagonist/central cough suppressant) + Expectorant + Sympathomimetic decongestant

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Zedex-Sf FAQs

What is Zedex-Sf used for?
Zedex-Sf is commonly used for Symptomatic relief of dry or productive cough associated with common cold/upper respiratory tract infections; helps relieve chest congestion and nasal stuffiness. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Zedex-Sf?
Zedex-Sf contains Dextromethorphan hydrobromide 10 mg + Guaifenesin 100 mg + Phenylephrine hydrochloride 5 mg per 5 ml. If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Zedex-Sf?
Oral syrup. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Zedex-Sf work?
Dextromethorphan suppresses the cough reflex by acting on the cough center in the brain.
Is Zedex-Sf a prescription medicine?
Yes. Zedex-Sf is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Zedex-Sf?
The side effects reported most often with Zedex-Sf are Drowsiness, dizziness, nausea, vomiting, stomach upset. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Zedex-Sf be taken during pregnancy?
Consult doctor Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Zedex-Sf.
Can I drink alcohol while taking Zedex-Sf?
Avoid
What if I miss a dose of Zedex-Sf?
Take it as soon as you remember.
Is Zedex-Sf habit forming?
No. Zedex-Sf is not known to be habit forming when taken as prescribed.
How much does Zedex-Sf cost on PingMeDoc Pharmacy?
Zedex-Sf starts at ₹199 (MRP ₹209) on PingMeDoc Pharmacy. Available in NA 100ML. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Zedex-Sf?
Zedex-Sf is manufactured by DR.REDDYS. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Zedex-Sf delivered?
Zedex-Sf is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Zedex-Sf, Quick facts

Salt
Dextromethorphan hydrobromide 10 mg + Guaifenesin 100 mg + Phenylephrine hydrochloride 5 mg per 5 ml
Best price
₹199 (₹1.99 per ml)
MRP
₹209
Prescription
Required (Rx)
Brand
Dr Reddys Laboratories Ltd
Manufacturer
DR.REDDYS
Therapeutic class
Cough & Cold Preparation (Antitussive/Expectorant/Decongestant)
Drug class
Antitussive (NMDA receptor antagonist/central cough suppressant) + Expectorant + Sympathomimetic decongestant
Habit forming
No
Variants
NA 100ML
Delivery
Standard across India

References

The information on Zedex-Sf is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. Manufacturer labeling/pack insert, established medical literature on dextromethorphan, guaifenesin and phenylephrine
  2. Indian drug labels/market data
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Zedex-Sf.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.