Zoryl-2

Composition of Zoryl-2

Zoryl-2 contains Glimepiride (2mg). It belongs to the Sulfonylurea class of medicines.

Uses of Zoryl-2

Type 2 diabetes mellitus (to control blood glucose) when diet and exercise alone are insufficient; may be used alone or with other antidiabetic medicines as prescribed.

Key benefits

• Helps lower blood glucose
• Improves glycaemic control in type 2 diabetes
• Reduces symptoms of hyperglycaemia
• Convenient once-daily dosing

How Zoryl-2 works

Glimepiride is a sulfonylurea that stimulates the pancreas to release insulin from beta cells. It also helps improve peripheral insulin sensitivity, lowering blood glucose levels.

How to take Zoryl-2

Oral tablet. Take exactly as prescribed, usually once daily with breakfast or the first main meal; swallow with water. Do not skip meals after taking; monitor blood sugar regularly.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you missed a a dose of Zoryl 2 Tablet, skip the missed dose and take your next dose at the usual time.

If you take too much

Taking more Zoryl-2 than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.

Side effects of Zoryl-2

Most side effects of Zoryl-2 are mild and settle as the body adjusts. Reported side effects include:

• Hypoglycaemia (low blood sugar)
• dizziness
• headache
• nausea
• abdominal pain
• diarrhoea
• weight gain
• skin rash

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Zoryl-2

Warnings and precautions

May cause hypoglycaemia—risk increases with missed meals, excessive exercise, alcohol, or with other antidiabetics. Use with caution in elderly, malnourished, renal or hepatic impairment; dose adjustment/close monitoring may be needed. Not for type 1 diabetes or diabetic ketoacidosis. Inform doctor if you have G6PD deficiency, allergies to sulfonylureas/sulfonamides, or if undergoing surgery/acute illness. Avoid driving/operating machinery if symptoms of low sugar occur.

Interactions with other medicines

Other antidiabetics/insulin (increased hypoglycaemia risk), alcohol (may worsen hypoglycaemia), beta-blockers (may mask hypoglycaemia symptoms), fluconazole and other azole antifungals (may increase effect), NSAIDs/salicylates (may increase effect), corticosteroids/diuretics (may raise glucose and reduce effect), rifampicin (may reduce effect), ACE inhibitors (may increase glucose-lowering effect)

How to store Zoryl-2

Store at room temperature (below 25°C), in a dry place, protected from light and moisture. Keep out of reach of children.

Expert advice for Zoryl-2

Take Zoryl 2 Tablet shortly before or with the first main meal of the day (usually breakfast). Exercise regularly, eat a healthy diet and take your other diabetes medicines (if prescribed) alongside. Monitor your blood sugar level regularly while you are taking Zoryl 2 Tablet. Zoryl 2 Tablet can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Be careful while driving or operating machinery until you know how Zoryl 2 Tablet affects you. Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor and anxiety. Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms, such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Manufacturer and class

Manufacturer:

INTAS PHARMACEUTICALS`

Therapeutic class:

Antidiabetic

Drug class:

Sulfonylurea

Chemical class:

Benzenesulfonamides