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Prescription requiredIntas Pharmaceuticals LtdAntidiabetic

Zoryl Mf 3

Glimepiride 3 mg + Metformin hydrochloride (modified/extended release) 500 mg

₹122MRP ₹1285% offIn stock
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Delivered across India in about 3–5 days, Chennai next day. ₹49 delivery, free above ₹999.

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Zoryl Mf 3 is used for type 2 diabetes mellitus (T2DM) in adults when diet and exercise alone or monotherapy is inadequate; helps control blood glucose levels.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Glimepiride 3 mg + Metformin hydrochloride (modified/extended release) 500 mg
Available variants: NA 10`S
Best price: ₹122
MRP: ₹128
Prescription: Required
Manufacturer: INTAS PHARMACEUTICALS`

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Zoryl Mf 3

Zoryl Mf 3 contains Glimepiride 3 mg + Metformin hydrochloride (modified/extended release) 500 mg. It belongs to the Sulfonylurea + Biguanide (combination) class of medicines.

Uses of Zoryl Mf 3

Type 2 diabetes mellitus (T2DM) in adults when diet and exercise alone or monotherapy is inadequate; helps control blood glucose levels

Key benefits

  • Lowers fasting and post-meal blood sugar
  • Improves insulin secretion and sensitivity
  • Helps achieve better HbA1c control
  • Convenient combination therapy

How Zoryl Mf 3 works

Glimepiride (a sulfonylurea) increases insulin release from pancreatic beta cells and improves insulin action. Metformin reduces glucose production by the liver and improves insulin sensitivity, decreasing intestinal glucose absorption and improving peripheral uptake.

How to take Zoryl Mf 3

Oral tablet. Take exactly as prescribed, usually once daily with or immediately after the main meal (often breakfast) to reduce stomach upset and risk of low sugar. Swallow whole (do not crush/chew if modified-release). Monitor blood glucose regularly.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Zoryl Mf 3

Most side effects of Zoryl Mf are mild and settle as the body adjusts. Reported side effects include:

  • Hypoglycaemia
  • nausea
  • vomiting
  • diarrhoea
  • abdominal pain
  • loss of appetite
  • metallic taste
  • headache
  • dizziness
  • weight gain
  • rash

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Zoryl Mf 3

PregnancyNot recommended (consult doctor; insulin is preferred in pregnancy)
BreastfeedingConsult your doctor before using this while breastfeeding.
AlcoholAvoid
DrivingMay cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
KidneyConsult your doctor if you have kidney disease.
LiverConsult your doctor if you have liver disease.
Habit formingNo

Warnings and precautions

Risk of hypoglycaemia (especially with missed meals, alcohol, heavy exercise, elderly, renal/hepatic impairment); metformin-associated lactic acidosis risk—avoid in severe kidney disease, severe liver disease, hypoxia, sepsis, dehydration. Check kidney function before and during therapy. Temporarily stop metformin for major surgery or iodinated contrast procedures as advised by doctor. Use caution in heart failure, alcohol use disorder, and in patients with vitamin B12 deficiency (long-term metformin).

Do not take Zoryl Mf if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.

Interactions with other medicines

Alcohol (increases hypoglycaemia/lactic acidosis risk), iodinated contrast media, insulin/other antidiabetics (additive hypoglycaemia), sulfonamide antibiotics, fluoroquinolones, beta-blockers (mask hypoglycaemia), corticosteroids and thiazide diuretics (raise glucose), ACE inhibitors (may increase hypoglycaemia), cimetidine (may increase metformin levels), NSAIDs (may increase hypoglycaemia)

How to store Zoryl Mf 3

Store below 25°C in a dry place, protected from moisture and light. Keep in original blister pack and out of reach of children.

Expert advice for Zoryl Mf 3

Take it shortly before a meal, and eat that meal. Check your sugar as often as your doctor has asked, especially when your routine changes. Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them.

Manufacturer and class

Manufacturer:
INTAS PHARMACEUTICALS`
Therapeutic class:
Antidiabetic
Drug class:
Sulfonylurea + Biguanide (combination)

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Zoryl Mf 3 FAQs

What is Zoryl Mf 3 used for?
Zoryl Mf 3 is commonly used for Type 2 diabetes mellitus (T2DM) in adults when diet and exercise alone or monotherapy is inadequate; helps control blood glucose levels. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Zoryl Mf 3?
Zoryl Mf 3 contains Glimepiride 3 mg + Metformin hydrochloride (modified/extended release) 500 mg. If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Zoryl Mf 3?
Oral tablet. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Zoryl Mf 3 work?
Glimepiride (a sulfonylurea) increases insulin release from pancreatic beta cells and improves insulin action.
Is Zoryl Mf 3 a prescription medicine?
Yes. Zoryl Mf 3 is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Zoryl Mf 3?
The side effects reported most often with Zoryl Mf are Hypoglycaemia, nausea, vomiting, diarrhoea, abdominal pain. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Zoryl Mf 3 be taken during pregnancy?
Not recommended (consult doctor; insulin is preferred in pregnancy) Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Zoryl Mf.
Can I drink alcohol while taking Zoryl Mf 3?
Avoid
What if I miss a dose of Zoryl Mf 3?
Take it as soon as you remember.
Is Zoryl Mf 3 habit forming?
No. Zoryl Mf 3 is not known to be habit forming when taken as prescribed.
How much does Zoryl Mf 3 cost on PingMeDoc Pharmacy?
Zoryl Mf 3 starts at ₹122 (MRP ₹128) on PingMeDoc Pharmacy. Available in NA 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Zoryl Mf 3?
Zoryl Mf 3 is manufactured by INTAS PHARMACEUTICALS`. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Zoryl Mf 3 delivered?
Zoryl Mf 3 is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Zoryl Mf 3, Quick facts

Salt
Glimepiride 3 mg + Metformin hydrochloride (modified/extended release) 500 mg
Best price
₹122
MRP
₹128
Prescription
Required (Rx)
Schedule
Schedule H
Brand
Intas Pharmaceuticals Ltd
Manufacturer
INTAS PHARMACEUTICALS`
Therapeutic class
Antidiabetic
Drug class
Sulfonylurea + Biguanide (combination)
Habit forming
No
Variants
NA 10`S
Delivery
Standard across India

References

Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.

  1. Manufacturer labeling/pack insert
  2. CDSCO/Indian market product information, established medical literature (ADA guidelines, standard pharmacology references)
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Zoryl Mf 3.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.